“What­ever you strug­gle with in a sense as it stems from your neu­rol­ogy, the inher­ent plas­tic­ity of the brain gives you a basis for improve­ment. This is a way under­uti­lized and under-appreciated resource that well all have.” Dr. Michael Merzenich on the Brain Sci­ence Pod­cast #54, 2/13/09.

Recently there has been grow­ing con­tro­versy about the effec­tive­ness of computer-based cog­ni­tive train­ing pro­grams. As a co-founder of Posit Sci­ence, Inc. Dr. Michael Merzenich is a staunch defender of the meth­ods his com­pany uses to val­i­date the pro­grams that they have devel­oped. But for the pur­poses of this essay, I want to share some of the key ideas we dis­cussed dur­ing his recent inter­view on the Brain Sci­ence Podcast.

First of all, I asked him to dis­cuss some of the high­lights of his long career. Since he was one of the first neu­ro­sci­en­tists to embrace the con­cepts of neu­ro­plas­tic­ity I was curi­ous about how this came about. While he did have some expo­sure to the ani­mal evi­dence as a grad­u­ate stu­dent, it was actu­ally his expe­ri­ence with the inven­tion of the cochlear implant that con­vinced Dr. Merzenich of the real-world, prac­ti­cal impli­ca­tions of brain plas­tic­ity. The qual­ity of the sig­nal pro­vided by a cochlear implant is rather poor com­pared to that pro­duced in nor­mal hear­ing, but over a period of months implant recip­i­ents are able to progress to the point of being able to dis­cern speech that sounds “almost nor­mal.” This is a prac­ti­cal exam­ple of brain plasticity.

You can learn more about this if you lis­ten to the inter­view, but I men­tion it here because it pro­vides an impor­tant point of con­ti­nu­ity between Dr. Merzenich’s early work with mon­keys and the work he went on to do with both Sci­en­tific Learn­ing, Inc. and Posit Sci­ence. Real­iz­ing that mon­keys’ abil­ity to under­stand speech was plas­tic lead to much of Dr. Merzenich’s later work. If you have been to the Posit Sci­ence web­site you know that their first pro­gram for older peo­ple is based on hear­ing. While I am sure the debate will con­tinue about the effec­tive­ness of this pro­gram, the sci­ence is inter­est­ing. We tend to be obsessed with mem­ory, and how it seems to be less effi­cient as we get older. So you might won­der where hear­ing fits in. Dr. Merzenich’s research indi­cates that as peo­ple get older their abil­ity to com­pre­hend rapid speech goes down. The key idea is that if you can improve hear­ing com­pre­hen­sion, mem­ory improves. This is because of the well-known fact that richer sig­nals leave stronger memories.

A sim­i­lar phe­nom­e­non has been observed with vision. As peo­ple get older they tend to spend more time focused directly in front of them­selves and less time sam­pling their sur­round­ings. Not only does this mean that they lit­er­ally see less of what is going on around them, it means their mem­o­ries are impov­er­ished. Thus, Posit Science’s new Insight pro­gram is based on train­ing peo­ple to regain the habit of fre­quently scan­ning the periph­ery that comes nat­u­rally when one is young.

I would hope that in addi­tion to exam­in­ing these pro­grams for effi­cacy, more researchers will build on the basic con­cepts to develop other programs.

While it is impor­tant to develop effec­tive pro­grams for cog­ni­tive fit­ness and improve­ment, Dr. Merzenich and I both think it is equally impor­tant that peo­ple embrace lifestyles that will uti­lize the brain plas­tic­ity that every­one has. When I asked him for advice he empha­sized the impor­tance of phys­i­cal activ­ity and the impor­tance of “remain­ing engaged in life.” If you want your brain to stay “sharp” you have to keep chal­leng­ing it. Avoid the temp­ta­tion to take the easy way out by inten­tion­ally try­ing things you aren’t already good at. “I am too old to learn …” is no longer a valid excuse!

Links:

- Brain Sci­ence Pod­cast #54: show notes to Episode 54 of the Brain Sci­ence Pod­cast with Dr. Michael Merzenich.

- Link to Audio File of Dr. Merzenich’s Interview

Gin­ger Camp­bell, MD grad­u­ated from the Uni­ver­sity of Alabama School of Med­i­cine. She also has a Master’s Degree in Bio­med­ical Engi­neer­ing and spent sev­eral years teach­ing at the Uni­ver­sity of Alabama in Birm­ing­ham. Dr. Camp­bell has been prac­tic­ing emer­gency med­i­cine since 1992. She started the Brain Sci­ence Pod­cast in 2006. Her goal is to help gen­eral audi­ences under­stand how recent dis­cov­er­ies in neu­ro­science are unrav­el­ing the mys­ter­ies of how our brains make us who we are.

Pre­vi­ous posts by Dr. Gin­ger Camp­bell, high­light­ing selected podcasts:

On Being Cer­tain: Believ­ing You Are Right Even When You’re Not.

Brain Sci­ence: “Brain Rules” Podcast.

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