neuro-plasticity

Technology as the missing link to enable a brain-based model of brain care: interview with Dr. John Docherty

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Dr. John Docher­ty is an Adjunct Pro­fes­sor of Psy­chi­a­try at the Weill Med­ical Col­lege, Cor­nell Uni­ver­si­ty, Direc­tor of Post Grad­u­ate Edu­ca­tion there, and Chief Med­ical Offi­cer of Brain Resource. Trained as a clin­i­cal research fel­low in neu­ropsy­chophar­ma­col­o­gy at NIMH, he lat­er returned as Chief of the Psy­choso­cial Treat­ments Research Branch, respon­si­ble for all fed­er­al­ly sup­port­ed psy­choso­cial treat­ment research in men­tal health nation­wide. He over­saw the land­mark Nation­al Col­lab­o­ra­tive Study of the Treat­ment of Depres­sion and served as a mem­ber and Chair­man for over 10 years on the NIMH and then NIDA Treat­ment Research IRGs. Dr. Docher­ty has wide expe­ri­ence in suc­cess­ful­ly imple­ment­ing inno­va­tion in both clin­i­cal oper­a­tions and man­aged health care. He found­ed North­east Psy­chi­atric Asso­ciates in 1985. As Nation­al Med­ical Direc­tor for Nation­al Med­ical Enter­pris­es, he over­saw med­ical con­trol and qual­i­ty improve­ment in 74 hos­pi­tals in 34 states. He was the Exec­u­tive Vice-Pres­i­dent and Chief Med­ical Offi­cer for Mer­it Behav­ioral Care, which then cov­ered 30 mil­lion peo­ple. In 1998, he found­ed Com­pre­hen­sive Neu­ro­Science (CNS). Its Care Man­age­ment Tech­nolo­gies are cur­rent­ly imple­ment­ed in 17 state Med­ic­aid plans. Dr Docher­ty has received numer­ous hon­ors and awards and has authored over 100 sci­en­tif­ic publications.

(Edi­tor’s note: this inter­view with Dr. John Docher­ty was orig­i­nal­ly pub­lished in Sharp­Brains’ mar­ket report Trans­form­ing Brain Health with Dig­i­tal Tools to Assess, Enhance and Treat Cog­ni­tion across the Lifes­pan, pub­lished in July 2010)

Alvaro Fer­nan­dez: Dr. Docher­ty, it is a plea­sure to be with you today to dis­cuss the main theme of Sharp­Brains’ 2010 mar­ket report – how the con­ver­gence of sci­en­tif­ic find­ings and tech­nol­o­gy plat­forms and tools is reshap­ing how as a soci­ety and as indi­vid­u­als we will take care of cog­ni­tion and men­tal well­ness along the life­course, giv­ing birth to the emerg­ing dig­i­tal brain health and fit­ness mar­ket. Can you first briefly dis­cuss your career tra­jec­to­ry and your cur­rent role at Brain Resource?

Dr. John Docher­ty: Sure. The main theme of my work since the 1960s has remained the same, “How do we put knowl­edge into effec­tive use to improve men­tal health?” Over the last cen­tu­ry, med­i­cine made tremen­dous progress in gen­er­at­ing sci­en­tif­ic and clin­i­cal knowl­edge. Basic research dis­cov­ery sci­ence and clin­i­cal treat­ment devel­op­ment sci­ence have made great progress. With­in Psy­chi­a­try there was stan­dard set­ting advance in the 1960’s through the NIMH-VA coop­er­a­tive stud­ies to the method­ol­o­gy of assess­ing the effi­ca­cy of psy­chophar­ma­co­log­i­cal drugs. This work estab­lished prin­ci­ples adopt­ed for the study of med­ica­tions in the oth­er areas of med­i­cine. The study of psy­chother­a­py, how­ev­er, lagged in devel­op­ment. In my role of Chief of the Psy­choso­cial Treat­ments Branch of the NIMH , I helped con­tribute to the advance of that work by sup­port­ing the efforts of an extra­or­di­nary group of indi­vid­u­als led by Irene Waskow who car­ried out the TDCRP. This study estab­lished the method­olo­gies that made pos­si­ble the effec­tive sci­en­tif­ic study of the effi­ca­cy of psy­chother­a­pies. The evi­dence base and of such treat­ments as CBT, DBT, Moti­va­tion­al Enhance­ment Treat­ment and oth­er evi­dence-based psy­chother­a­pies derives direct­ly from this study and its sem­i­nal influ­ence. This was a con­tri­bu­tion to the sci­ence of Clin­i­cal Treat­ment Devel­op­ment research.

I would say that my major inter­est, how­ev­er, has been in the next step, the sci­ence of knowl­edge trans­fer. There has been and remains a long and cost­ly (in terms par­tic­u­lar­ly of unnec­es­sary suf­fer­ing) lag between the devel­op­ment of new knowl­edge and its com­mon and effec­tive use in practice.

In order the help the field moved for­ward, I have worked for the last 20 years in the devel­op­ment and imple­men­ta­tion of meth­ods to effec­tive­ly trans­fer knowl­edge into prac­tice. [Read more…] about Tech­nol­o­gy as the miss­ing link to enable a brain-based mod­el of brain care: inter­view with Dr. John Docherty

The Brain Fitness Program DVD (Michael Merzenich)

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The most pop­u­lar ques­tion we got when we announced that PBS had a great spe­cial on Brain Fit­ness Pro­gram and Neu­ro­plas­tic­i­ty in Decem­ber was, when will the DVD be available?

Well, final­ly here it comes. You can click on the image or the title to go over to PBS shop to learn more and buy it.

The Brain Fit­ness Pro­gram DVD ($24.95, shipped by 02/01/08). “This pro­gram presents a work­out to help view­ers get their brains in bet­ter shape. The Brain Fit­ness Pro­gram is based on neu­ro-plas­tic­i­ty, the abil­i­ty of the brain to change and adapt — even rewire itself. In the past two years, a team of sci­en­tists has devel­oped com­put­er-based stim­u­lus sets that dri­ve ben­e­fi­cial chem­i­cal, phys­i­cal and func­tion­al changes in the brain. Dr. Michael Merzenich of the Uni­ver­si­ty of Cal­i­for­nia San Fran­cis­co and his col­leagues around the world have been lead­ing this effort; he brings the research find­ings, along with a sci­en­tif­i­cal­ly based set of brain exer­cis­es, to PBS view­ers in this inno­v­a­tive and life-alter­ing pro­gram. Peter Coy­ote narrates. ”

To pur­chase: click Here.

You can watch a 3‑minute trail­er: click here.

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Note: How can any­one take care of his or her brain when every week brings a new bar­rage of arti­cles and stud­ies which seem to con­tra­dict each other?

Do sup­ple­ments improve mem­o­ry? Do you need both phys­i­cal and men­tal exer­cise –or is one of them enough? Why is man­ag­ing stress so impor­tant to atten­tion and mem­o­ry? Which brain train­ing approach, if any, is worth one’s time and money?

SharpBrainsGuide_3DIf you have these ques­tions, check out this new book, The Sharp­Brains Guide to Brain Fit­ness:

“Final­ly, an insight­ful and com­plete overview of the sci­ence, prod­ucts and trends to debunk old myths and help us all main­tain our brains in top shape. A must-read”
—Glo­ria Cavanaugh, for­mer Pres­i­dent & CEO of the Amer­i­can Soci­ety on Aging and found­ing Board mem­ber of the Nation­al Alliance for Care­giv­ing”
Kudos for an excel­lent resource! This Sharp­Brains Guide is full of top notch infor­ma­tion, pro­vides prac­ti­cal tips and helps sep­a­rate hype from hope in the brain health arena.”
—Eliz­a­beth Edger­ly, Ph.D., Chief Pro­gram Offi­cer, Alzheimer’s Association
“A mas­ter­ful guide to the brain train­ing rev­o­lu­tion. Promis­es to stim­u­late a much need­ed con­ver­sa­tion that will nudge soci­ety to build a new brain fit­ness cul­ture on sol­id, research-based, foundations.”
—P. Murali Doraiswamy MD, Pro­fes­sor of Psy­chi­a­try, Duke Uni­ver­si­ty and Co-author of The Alzheimer’s Action Plan

Brain Fitness Program and Neuroplasticity @ PBS

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Update (11/10/10): Have you seen PBS great spe­cials on Brain Fit­ness and Neu­ro­plas­tic­i­ty ?

The Brain Fit­ness Pro­gram DVD ($24.95)

“The Brain Fit­ness Pro­gram is based on the brain’s abil­i­ty to change and adapt, even rewire itself. In the past two years, a team of sci­en­tists has devel­oped com­put­er-based stim­u­lus sets that dri­ve ben­e­fi­cial chem­i­cal, phys­i­cal and func­tion­al changes in the Peter Coyote Brain Fitness Programbrain. Dr. Michael Merzenich of the Uni­ver­si­ty of Cal­i­for­nia and his col­leagues share their sci­en­tif­i­cal­ly based set of brain exer­cis­es in this life-alter­ing pro­gram. Peter Coy­ote (pic­tured) narrates. ”

PBS aired in Decem­ber 2007 a spe­cial pro­gram on neu­ro­plas­tic­i­ty, brain fit­ness, aging and the brain titled “Brain Fit­ness Pro­gram”. To watch the 3‑minute trail­er: click here.

In 2008, PBS released a sec­ond DVD: 

Brain Fit­ness 2: Sight and Sound DVD ($24.95)

“This pro­gram, specif­i­cal­ly designed to help peo­ple get the most from their vision and hear­ing as they age, con­sid­ers how these sens­es change through­out life and what peo­ple can do to keep them healthy and ful­ly functional.”

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If you do not have time to watch these great doc­u­men­taries, here are a few points one needs to under­stand about neuroplasticity:

1.  The human brain is now con­sid­ered to be a high­ly dynam­ic and con­stantly reor­ga­niz­ing sys­tem capa­ble of being shaped and reshaped across an entire lifes­pan. It is believed that every expe­ri­ence alters the brain’s orga­ni­za­tion at some lev­el. The key words in this new approach to the brain are neu­ro­plas­tic­ity and neu­ro­ge­n­e­sis. Neu­ro­plas­tic­ity refers to the life­long capac­ity of the brain to change and rewire itself in response to the stim­u­la­tion of learn­ing and expe­ri­ence. Neu­ro­ge­n­e­sis is the abil­ity to cre­ate new neu­rons and con­nec­tions between neu­rons through­out a life­time. The lat­ter process is also referred to as synap­to­ge­n­e­sis. This new par­a­digm con­trasts with tra­di­tional ideas of the human brain being a fixed and essen­tially lim­ited sys­tem that only degrades with age.

2. As we age, the rate of change in the brain, or neu­ro­plas­tic­ity, declines but does not come to a halt. In addi­tion, we now know that new neu­rons can appear in cer­tain parts of the brain up until the day we die.

3. Brain plas­tic­ity is cru­cial fol­low­ing head injury. It is the one brain’s abil­ity that allows recov­ery. Brain plas­tic­ity is also the abil­ity that brain train­ing takes advan­tages of to try to slow down the aging process.

To read about evi­dence of neu­ro­plas­tic­i­ty in the human brain take a look at Brain plas­tic­i­ty: How learn­ing changes you brain

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Note: How can any­one take care of his or her brain when every week brings a new bar­rage of arti­cles and stud­ies which seem to con­tra­dict each other?

Do sup­ple­ments improve mem­o­ry? Do you need both phys­i­cal and men­tal exer­cise –or is one of them enough? Why is man­ag­ing stress so impor­tant to atten­tion and mem­o­ry? Which brain train­ing approach, if any, is worth one’s time and money?

If you have these ques­tions, check out this new book, The Sharp­Brains Guide to Brain Fit­ness:

“Final­ly, an insight­ful and com­plete overview of the sci­ence, prod­ucts and trends to debunk old myths and help us all main­tain our brains in top shape. A must-read”
—Glo­ria Cavanaugh, for­mer Pres­i­dent & CEO of the Amer­i­can Soci­ety on Aging and found­ing Board mem­ber of the Nation­al Alliance for Caregiving
“Kudos for an excel­lent resource! This Sharp­Brains Guide is full of top notch infor­ma­tion, pro­vides prac­ti­cal tips and helps sep­a­rate hype from hope in the brain health arena.”
—Eliz­a­beth Edger­ly, Ph.D., Chief Pro­gram Offi­cer, Alzheimer’s Association

“A mas­ter­ful guide to the brain train­ing rev­o­lu­tion. Promis­es to stim­u­late a much need­ed con­ver­sa­tion that will nudge soci­ety to build a new brain fit­ness cul­ture on sol­id, research-based, foundations.”
—P. Murali Doraiswamy MD, Pro­fes­sor of Psy­chi­a­try, Duke Uni­ver­si­ty and Co-author of The Alzheimer’s Action Plan

The Sharp­Brains Guide to Brain Fitness
SharpBrains Guide to Brain Fitness. The Book Click

Here

to order at Amazon.com.
Print Edi­tion, $24.95

SharpBrains Guide to Brain Fitness. The Book Click

Here

to order at Amazon.com,
Kin­dle Edi­tion, $9.99

Can Thoughts and Action Change Our Brains?

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We final­ly had time to hear and enjoy the 35-minute inter­view with WSJ sci­ence writer Sharon Beg­ley about her new book, Train Your Mind Change Your Brain. High­ly rec­om­mend­ed. (Thanks Beate!)

NPR Talk of the Nation, Feb­ru­ary 2, 2007: “For years, sci­en­tists believed the brain’s struc­ture could­n’t be changed. The new sci­ence of neu­ro­plas­tic­i­ty says that’s not the case, and argue the brain is much more flex­i­ble than pre­vi­ous­ly thought.”

Lis­ten to the inter­view here.