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Persistence pays off: After 8‑year follow-up, study finds robust and sustained antidepressant response to deep brain stimulation (DBS)

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Long-Term Fol­low-Up Data Shows Deep Brain Stim­u­la­tion Is an Effec­tive Treat­ment for Treat­ment-Resis­tant Depres­sion (Mount Sinai press release):

A study pub­lished online on Fri­day, Octo­ber 4, in The Amer­i­can Jour­nal of Psy­chi­a­try found that deep brain stim­u­la­tion (DBS) of an area in the brain called the sub­cal­los­al cin­gu­late (SCC) pro­vides a robust anti­de­pres­sant effect that is sus­tained over a long peri­od of time in patients with treat­ment-resis­tant depres­sion Read the rest of this entry »

Therapy or antidepressants? Coming soon: Brain activity “fingerprints” to personalize depression treatments

mental health.

To Treat Depres­sion, Drugs or Ther­a­py? (The New York Times):

Until recent­ly, many experts thought that your clin­i­cian could lit­er­al­ly pick any anti­de­pres­sant or type of psy­chother­a­py at ran­dom because, with a few clin­i­cal excep­tions, there was lit­tle evi­dence to favor one treat­ment over anoth­er for a giv­en patient Read the rest of this entry »

Should Cognitive Behavioural Therapy (not antidepressant drugs) be the first-line treatment for depression?

CBT_brain

Depres­sion: A change of mind (Nature):

Cog­ni­tive ther­a­py, com­mon­ly known as cog­ni­tive behav­iour­al ther­a­py (CBT), aims to help peo­ple to iden­ti­fy and change neg­a­tive, self-destruc­tive thought pat­terns. And although it does not work for every­one with depres­sion, data have been accu­mu­lat­ing in its favour. “CBT is one of the clear suc­cess sto­ries in psy­chother­a­py,” says Ste­fan Hof­mann, a psy­chol­o­gist at Boston Uni­ver­si­ty in Mass­a­chu­setts…

Anti­de­pres­sant drugs are usu­al­ly the first-line treat­ment for depres­sion. Read the rest of this entry »

To treat depression, we will likely combine neuroplasticity-based brain training games with antidepressants

BrainTrainingCom­put­er Games Bet­ter Than Med­ica­tion in Treat­ing Elder­ly Depres­sion (Live Sci­ence):

Com­put­er games could help in treat­ing old­er peo­ple with depres­sion who haven’t been helped by anti­de­pres­sant drugs or oth­er treat­ments for the disorder…In a study of 11 old­er patients, researchers found play­ing cer­tain com­put­er games was just as effec­tive at reduc­ing symp­toms of depres­sion as Read the rest of this entry »

There’s no single silver bullet to treat depression (not even aerobic exercise)

Exer­cise And Depres­sion Revis­it­ed (Neu­roskep­tic blog):

A new study has found lit­tle evi­dence that aer­o­bic exer­cise helps treat depres­sion, con­trary to pop­u­lar belief…Danish researchers Krogh and col­leagues ran­dom­ly 115 assigned depressed peo­ple to one of two exer­cise pro­grams. One was a stren­u­ous aer­o­bic work­out — cycling for 30 min­utes, 3 times per week, for 3 months. The oth­er was var­i­ous stretch­ing exercises…Both groups got less depressed but there was zero dif­fer­ence between the two con­di­tions. The cyclists did get phys­i­cal­ly fit­ter than the stretch­ers, los­ing more weight and improv­ing on oth­er mea­sures. But they did­n’t feel any better…If this is true, it might mean that  Read the rest of this entry »

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As seen in The New York Times, The Wall Street Journal, BBC News, CNN, Reuters,  SharpBrains is an independent market research firm tracking how brain science can improve our health and our lives.

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