Sharp Brains: Brain Fitness and Cognitive Health News

Neuroplasticity, Brain Fitness and Cognitive Health News

Icon

To treat depression, we will likely combine neuroplasticity-based brain training games with antidepressants

BrainTrainingCom­put­er Games Bet­ter Than Med­ica­tion in Treat­ing Elder­ly Depres­sion (Live Sci­ence):

Com­put­er games could help in treat­ing old­er peo­ple with depres­sion who haven’t been helped by anti­de­pres­sant drugs or oth­er treat­ments for the disorder…In a study of 11 old­er patients, researchers found play­ing cer­tain com­put­er games was just as effec­tive at reduc­ing symp­toms of depres­sion as the “gold stan­dard” anti­de­pres­sant drug esc­i­talo­pram. More­over, those patients play­ing the com­put­er games achieved results in just four weeks, com­pared to the 12 weeks it often takes with esc­i­talo­pram (also known by its brand name, Lexapro)…

Anti­de­pres­sant drugs have side effects that may make peo­ple wary of tak­ing them, but not treat­ing the ill­ness can have even more seri­ous con­se­quences, Mori­mo­to said…

The researchers not­ed this was a very small pre­lim­i­nary study, and they want to con­duct a ran­dom­ized con­trolled tri­al, Mori­mo­to said. This com­put­er ther­a­py could be used by itself or in con­junc­tion with anti­de­pres­sant drugs, Mori­mo­to said.”

Study: Neu­ro­plas­tic­i­ty-based com­put­er­ized cog­ni­tive reme­di­a­tion for treat­ment-resis­tant geri­atric depres­sion (Nature Com­mu­ni­ca­tions)

  • Abstract: Exec­u­tive dys­func­tion (ED) in geri­atric depres­sion (GD) is com­mon, pre­dicts poor clin­i­cal out­comes and often per­sists despite remis­sion of symp­toms. Here we devel­op a neu­ro­plas­tic­i­ty-based com­put­er­ized cog­ni­tive reme­di­a­tion-geri­atric depres­sion treat­ment to tar­get ED in GD. Our assump­tion is that reme­di­a­tion of these deficits may mod­u­late the under­ly­ing brain net­work abnor­mal­i­ties shared by ED and depres­sion. We com­pare the inter­ven­tion to a gold-stan­dard treat­ment (?esc­i­talo­pram: 20?mg per 12 weeks) in 11 treat­ment-resis­tant old­er adults with major depres­sion; and 33 matched his­tor­i­cal con­trols. We find that 91% of par­tic­i­pants com­plete the inter­ven­tion, which is equal­ly as effec­tive at reduc­ing depres­sive symp­toms as ?esc­i­talo­pram but does so in 4 weeks instead of 12. In addi­tion, the inter­ven­tion improves mea­sures of exec­u­tive func­tion more than the ?esc­i­talo­pram. We con­clude that this neu­ro­plas­tic­i­ty-based com­put­er­ized treat­ment may be equal­ly effec­tive as ?esc­i­talo­pram in treat­ing GD. In addi­tion, par­tic­i­pants showed greater improve­ment in exec­u­tive func­tions than his­tor­i­cal con­trols treat­ed with ?esc­i­talo­pram.

Learn more:

Leave a Reply...

Loading Facebook Comments ...

Leave a Reply

Categories: Cognitive Neuroscience, Health & Wellness, Technology

Tags: , , , , , , , , , , , ,

Watch All Recordings Now (40+ Speakers, 12+ Hours)

About SharpBrains

As seen in The New York Times, The Wall Street Journal, BBC News, CNN, Reuters and more, SharpBrains is an independent market research firm tracking health and performance applications of brain science.

Follow us and Engage via…

twitter_logo_header
RSS Feed

Search for anything brain-related in our article archives