Top researchers who advised the U.S. Food and Drug Administration on Biogen Inc.’s Alzheimer’s drug blasted the agency for approving it, calling the decision a “regulatory failure” that is “at odds with the evidence.” [Read more…] about Alzheimer’s & Dementia researchers challenge FDA’s approval of Aduhelm given lack of evidence for beta-amyloid as a marker
Kenneth S. Kosik, MD, and Ellen Clegg, authors of a recent book on Alzheimer’s Disease prevention and treatment, forcefully propose a new framework and model for brain care: What about setting up “cognitive shops” as “a sort of one-stop shopping for everything from Alzheimer’s disease prevention to guided care for mild or moderate disease”. What follows is the thought-provoking conclusion section from their book “The Alzheimer’s Solution. How Today’s Care Is Failing Millions and How We Can Do Better” (reproduced with permission), not very different from the “brain fitness center” model we have talked about in the past.
Chapter 10. CONCLUSIONS
Just as the idea of hospice care revolutionized death and dying in America, the idea of bundling many aspects of Alzheimer’s care under one roof in a cognitive shop could change the way we approach this dire disease—one that has no cure and leaves no survivors. Certainly, the scope of the problem poses medical and economic risks for the country. These risks, and potential steps for a solution, were charted by the bipartisan Alzheimer Study Group in the spring of 2009. The report, issued by the Alzheimer Study Group co-chaired by former congressman Newt Gingrich and former senator Bob Kerrey, minces few words. [Read more…] about Rethinking Alzheimer’s Prevention and Treatment: The Cognitive Shop/ Brain Fitness Center
(Editor’s Note: I recently came across an excellent book and resource, The Alzheimer’s Action Plan: The Experts’ Guide to the Best Diagnosis and Treatment for Memory Problems, recently released in paperback. Dr. Murali Doraiswamy, one of the authors and leading Alzheimer’s expert, kindly helped us create a 2‑part article series to share with SharpBrains readers advice on a very important question, “How can we help the public at large to distinguish Alzheimer’s Disease from normal aging — so that an interest in early identification doesn’t translate into unneeded worries?” What follows is an excerpt from the book, pages 72–78, discussing the Pros and Cons of the most common assessments).
While no single test (other than a brain biopsy, which is a very invasive and risky procedure) can conclusively prove that a person has Alzheimer’s, many tests can give us a good idea. A list of all the tests that help us assess memory and thinking problems appears at the end of this chapter. Meanwhile, let’s take a good look at the whys and hows of a thorough memory assessment.
WHAT A DIFFERENCE AN EXTRA TEST CAN MAKE
To understand why getting tested (and retested as symptoms change and the disease progresses) is important, check out the experience of Katherine, who went to the doctor complaining of a memory slowdown. She took five of the most important neuropsychological tests, which assess brain function without actually physically looking at the brain. Then she underwent brain scans, a cardiovascular workup, and blood tests to see what else was going on that might be undermining her mental function. [Read more…] about The Best Memory Tests: Mini-Mental and Beyond (Alzheimer’s Action Plan)