Should doctors prescribe Leqembi (lecanemab) to women with early Alzheimer’s Disease? The evidence-based answer is probably No

By SharpBrains | June 28, 2023

Wel­come to a new edi­tion of Sharp­Brains e‑newsletter, fea­tur­ing this time a range of inter­ven­tions for brain/ cognitive/ men­tal health plus a few brain teasers to test our per­cep­tion and cog­ni­tive skills. #1. Should doc­tors pre­scribe lecanemab (Leqem­bi) to women? The answer, giv­en avail­able evi­dence, is prob­a­bly No Huge (and most­ly over­looked) red flag regard­ing newly…

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Should doctors prescribe lecanemab (Leqembi) to women? The answer, given available evidence, is probably No

By Prof. Michael Valenzuela | May 10, 2023

Data from the CLARITY tri­al ear­li­er this year was sup­posed to be the crown­ing glo­ry of the amy­loid hypoth­e­sis, vin­di­ca­tion for pro­po­nents of this long-held but much-maligned the­o­ry of Alzheimer’s dis­ease. Yet the results left many feel­ing under­whelmed, and even the study authors non­com­mit­tal. The CLARITY tri­al has many admirable fea­tures. It recruit­ed close to…

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