The U.S. Food and Drug Administration has approved a clinical trial using a neuroimaging helmet made by Los Angeles-based Kernel to track what happens in the brain when a human takes a psychedelic dose of ketamine. [Read more…] about FDA-approved, Cybin-sponsored clinicial trial to measure ketamine’s impact on the brain via Kernel Flow neuroimaging helmet
Dr. Michael Merzenich, Emeritus Professor at UCSF, is a leading pioneer in brain plasticity research. In the late 1980s, Dr. Merzenich was on the team that invented the cochlear implant. In 1996, he was the founding CEO of Scientific Learning Corporation (Nasdaq: SCIL), and in 2004 became co-founder and Chief Scientific Officer of Posit Science. He was elected to the National Academy of Sciences in 1999 and to the Institute of Medicine this year. He retired as Francis A. Sooy Professor and Co-Director of the Keck Center for Integrative Neuroscience at the University of California at San Francisco in 2007. You may have learned about his work in one of PBS TV specials, multiple media appearances, or neuroplasticity-related books.
(Alvaro Fernandez) Dear Michael, thank you very much for agreeing to participate in the inaugural SharpBrains Virtual Summit in January, and for your time today. In order to contextualize the Summit’s main themes, I would like to focus this interview on the likely big-picture implications during the next 5 years of your work and that of other neuroplasticity research and industry pioneers.
Thank you for inviting me. I believe the SharpBrains Summit will be very useful and stimulating, you are gathering an impressive group together. I am looking forward to January.
Neuroplasticity-based Tools: The New Health & Wellness Frontier
There are many different technology-free approaches to harnessing/ enabling/ driving neuroplasticity. What is the value that technology brings to the cognitive health table?
It’s all about efficiency, scalability, personalization, and assured effectiveness. Technology supports the implementation of near-optimally-efficient brain-training strategies. Through the Internet, it enables the low-cost distribution of these new tools, anywhere out in the world. Technology also enables the personalization of brain health training, by providing simple ways to measure and address individual needs in each person’s brain-health training experience. It enables assessments of your abilities that can affirm that your own brain health issues have been effectively addressed.
Of course substantial gains could also be achieved by organizing your everyday activities that grow your neurological abilities and sustain your brain health. Still, if the ordinary citizen is to have any real chance of maintaining their brain fitness, they’re going to have to spend considerable time at the brain gym!
One especially important contribution of technology is the scalability that it provides for delivering brain fitness help out into the world. Think about how efficient the drug delivery system is today. Doctors prescribe drugs, insurance covers them, and there is a drug store in every neighborhood in almost every city in the world so that every patient has access to them. Once neuroplasticity-based tools and outcomes and standardized, we can envision a similar scenario. And we don’t need all those drug stores, because we have the Internet!
Having said this, there are obvious obstacles. One main one, in my mind, is the lack of understanding of what these new tools can do. Cognitive training programs, for example, seem counter-intuitive to consumers and many professionals “ why would one try to improve speed-of-processing if all one cares about is memory? A second obvious problem is to get individuals to buy into the effort required to really change their brains for the better. That buy-in has been achieved for many individuals as it applies to their physical health, but we haven’t gotten that far yet in educating the average older person that brain fitness training is an equally effortful business!
Tools for Safer Driving: Teens and Adults
Safe driving seems to be one area where the benefits are more intuitive, which may explain the significant traction.
Yes, we see great potential and interest among insurers for improving driving safety, both for seniors and teens. Appropriate cognitive training can lower at-fault accident rates. You can measure clear benefits in relatively short time frames, so it won’t take long for insurers to see an economic rationale to not only offer programs at low cost or for free but to incentivize drivers to complete them. Allstate, AAA, State Farm and other insurers are beginning to realize this potential. It is important to note that typical accidents among teens and seniors are different, so that training methodologies will need to be different for different high-risk populations.
Yet, most driving safety initiatives today still focus on educating drivers, rather that training them neurologically. We measure vision, for example, but completely ignore attentional control abilities, or a driver’s useful field of view. I expect this to change significantly over the next few years.
Long-term care and health insurance companies will ultimately see similar benefits, and we believe that they will follow a similar course of action to reduce general medical and neurodegenerative disease- (Mild Cognitive Impairment and Alzheimer’s- and Parkinsons-) related costs. In fact, many senior living communities are among the pioneers in this field.
Boomers & Beyond: Maintaining Cognitive Vitality
Mainstream media is covering this emerging category with thousands of stories. But most coverage seems still focused on does it work? more than “how do we define It”, what does work mean? or work for whom, and for what? Can you summarize what recent research suggests?
We have seen clear patterns in the application of our training programs, some published (like IMPACT), some unpublished, some with healthy adults, and some with people with mild cognitive impairment or early Alzheimers Disease (AD). What we see in every case: [Read more…] about Michael Merzenich on Brain Training, Assessments, and Personal Brain Trainers