cognitive healthcare

On building better brains at any age, treating Depression vs. Dementia, emerging neurotechnologies, psychedelics, and more

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Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing eleven new research find­ings and inno­v­a­tive resources for life­long cog­ni­tive and brain health.

#1. Debate: Are depres­sion and demen­tia two sides of the same coin? And, if they are, how to best approach treatment?

#2. Either way, the ear­li­er the bet­ter, but it’s nev­er too late: New book out­lines the five lifestyle pil­lars to “build a bet­ter brain at any age”

#3. “If I were a car­di­ol­o­gist eval­u­at­ing a patient’s chest pain, for instance, I would speak with the patient, but then I would lis­ten to their heart and mea­sure their pulse and blood pres­sure. I might order an elec­tro­car­dio­gram or a car­diac stress test, tools that weren’t avail­able a cen­tu­ry ago. Because I’m a psy­chi­a­trist, how­ev­er, I eval­u­ate patients in pre­cise­ly the same way that my pre­de­ces­sors did in 1920…” Read­ing Our Minds: New book issues strong call to action to mod­ern­ize psychiatry

#4. Very time­ly effort by Well­come in the UK: Com­pre­hen­sive research review iden­ti­fies most promis­ing inter­ven­tions to boost work­place men­tal health

#5. “As we enter the sec­ond year of the pan­dem­ic, so many peo­ple are strug­gling and seek­ing men­tal health sup­port. Wysa is an exam­ple of how tech­nol­o­gy is help­ing mil­lions of peo­ple access every­day men­tal health sup­port and self-care tools with­out being gat­ed by a clin­i­cal diag­no­sis.” — Dr. Pankaj Jeth­wani, Exec­u­tive Vice Pres­i­dent at W Health Ven­tures. Arti­fi­cial Intel­li­gence (AI)-enabled chat­bot Wysa rais­es $5.5M to broad­en access to men­tal health support

#6. Study: Social media and gen­er­al tech engage­ment not found to “fry” teenagers’ brains

#7. Akili Inter­ac­tive Labs rais­es $160M in equi­ty and debt to trans­form cog­ni­tive health­care via pre­scrip­tion videogame treat­ments. A nice way to cel­e­brate Akil­i’s 10th anniver­sary … they are tar­get­ing ADHD first (now kids, lat­er teens and adults), to be fol­lowed by treat­ments for a range of cog­ni­tive dis­or­ders relat­ed to depres­sion, Mul­ti­ple Scle­ro­sis, Autism, “Covid-Fog” and more.

#8. Study: High­er men­tal well­be­ing (in 2016) seen to low­er health­care costs (in 2017). We still have time to invest in pub­lic men­tal well­be­ing in 2021.

#9. Teladoc Health, hav­ing acquired Livon­go and myS­trength, launch­es inte­grat­ed men­tal health ser­vice for the work­place. “The announce­ment comes as more than half of peo­ple with men­tal health con­cerns report that they do not know where to start when get­ting care, high­light­ing the impor­tance of the dig­i­tal front door myS­trength Com­plete will pro­vide…” This is indeed a very com­mon pain point accord­ing to our own research, so good to see the quite com­pre­hen­sive & per­son­al­ized approach.

#10. Cumu­lus Neu­ro­science rais­es $8.3M to devel­op EEG-based wire­less ‘Fit­bit for the brain’ — Fas­ci­nat­ing to see the major role of the Demen­tia Dis­cov­ery Fund, in a bid to accel­er­ate clin­i­cal tri­als and poten­tial therapies.

#11. Last but not least, a very promis­ing clin­i­cal appli­ca­tion of psy­che­delics: Study finds MDMA-assist­ed ther­a­py to be safe and high­ly effec­tive to treat severe PTSD. “The Nature authors spec­u­late that MDMA-assist­ed ses­sions pro­duce a “win­dow of tol­er­ance,” in which patients are able to revis­it trau­mat­ic mem­o­ries, with less shame and anger, and with­out being over­whelmed by PTSD symptoms.”

Wish­ing you a healthy Memo­r­i­al Week­end and month of June,

The Sharp­Brains Team

Akili Interactive Labs raises $160M in equity and debt to transform cognitive healthcare via prescription videogame treatments

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Akili rais­es $110m to build its dig­i­tal ther­a­peu­tics pipeline (phar­mafo­rum):

Endeav­or­Rx became the first and so far only approved pre­scrip­tion video game treat­ment in the US when it was cleared by the FDA last year to treat atten­tion-deficit hyper­ac­tiv­i­ty dis­or­der (ADHD), and has also been giv­en a green light in Europe. [Read more…] about Akili Inter­ac­tive Labs rais­es $160M in equi­ty and debt to trans­form cog­ni­tive health­care via pre­scrip­tion videogame treatments

BrainCheck raises $8 million to digitize cognitive/ neuropsychological assessments and better serve the aging population

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This start­up just raised $8 mil­lion to help busy doc­tors assess the cog­ni­tive health of 50 mil­lion seniors (TechCrunch):

“…star­tups increas­ing­ly rec­og­nize oppor­tu­ni­ties to cater to this aging pop­u­la­tion. Some are devel­op­ing prod­ucts to sell to indi­vid­u­als and their fam­i­ly mem­bers direct­ly; oth­ers are com­ing up with ways to empow­er those who work direct­ly with old­er Americans.

BrainCheck, a 20-per­son, Hous­ton-based start­up whose cog­ni­tive health­care prod­uct aims to help physi­cians assess and track the men­tal health of their patients, is among the lat­ter. Investors like what it has put togeth­er, too. Today, the start­up is announc­ing $8 mil­lion in Series A fund­ing co-led by S3 Ven­tures and Ten­sil­i­ty Ven­ture Part­ners. [Read more…] about BrainCheck rais­es $8 mil­lion to dig­i­tize cognitive/ neu­ropsy­cho­log­i­cal assess­ments and bet­ter serve the aging population

Final days to submit scalable & non-pharmacological Brain Health proposals to MIT Solve’s Brain Health Challenge

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Insuf­fi­cient brain health­care is one of the most per­va­sive and mul­ti-faceted prob­lems our world faces today. From the young to the old, the rich to the poor, those liv­ing in dense cities to iso­lat­ed farm­lands, any­one can be affect­ed by brain health prob­lems. Yet, cur­rent solu­tions to this prob­lem are lim­it­ed. While some inno­va­tions have made sig­nif­i­cant strides towards improved brain health, there is a press­ing need for stronger pri­or­i­ti­za­tion of cog­ni­tive health­care and more proac­tive inno­va­tion towards pre­ven­ta­tive treat­ments. [Read more…] about Final days to sub­mit scal­able & non-phar­ma­co­log­i­cal Brain Health pro­pos­als to MIT Solve’s Brain Health Challenge

Applying to MIT Solve? Here are 4 Ways, and 20 Resources, to Upgrade Brain Health in the Digital Age

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Insuf­fi­cient brain health­care is one of the most per­va­sive and mul­ti-faceted prob­lems our world faces today. From the young to the old, the rich to the poor, those liv­ing in dense cities to iso­lat­ed farm­lands, any­one can be affect­ed by brain health prob­lems. Yet, cur­rent solu­tions to this prob­lem are lim­it­ed. While some inno­va­tions have made sig­nif­i­cant strides towards improved brain health, there is a press­ing need for stronger pri­or­i­ti­za­tion of cog­ni­tive health­care and more proac­tive inno­va­tion towards pre­ven­ta­tive treatments.

Here’s what the new MIT Solve 2017 Glob­al Chal­lenge says about brain health:

“Brain and men­tal well-being are crit­i­cal to the health and hap­pi­ness of the 7.5 bil­lion peo­ple who inhab­it our planet…shifting the con­ver­sa­tion from treat­ing brain dis­eases to improv­ing well-being may begin to dis­solve the cul­tur­al stig­ma that makes it dif­fi­cult for many to seek help.”

Con­tin­ue read­ing the arti­cle Four Ways to Upgrade Brain Health in the Dig­i­tal Age, by Sharp­Brains’ Alvaro Fer­nan­dez, with guide­lines and resources to:

  1. Pri­or­i­tize scal­able solu­tions for all
  2. Har­ness life­long neuroplasticity
  3. Har­ness per­va­sive tech­nolo­gies and arti­fi­cial intel­li­gence (AI)
  4. Edu­cate users and encour­age human-cen­tered innovation