Otsuka Pharmaceutical is launching a virtual study to see if digital therapeutics can reduce depression symptoms.
It’s the next step in a partnership between the Tokyo-based drugmaker and Click Therapeutics, a digital health startup that is developing programs for smoking cessation, depression and insomnia. [Read more…] about Innovation in COVID times: Otsuka and Click Therapeutics announce fully virtual clinical trial, leveraging Verily’s Project Baseline
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring fascinating findings, books and resources for lifelong brain health.
#1. “The human brain (section; left image above) functions thanks to its wide neuronal network that is deemed to contain approximately 69 billion neurons. On the other hand, the observable universe (section simulation; right image) can count upon a cosmic web of at least 100 billion galaxies. Within both systems, only 30% of their masses are composed of galaxies and neurons. Within both systems, galaxies and neurons arrange themselves in long filaments or nodes between the filaments. Finally, within both systems, 70% of the distribution of mass or energy is composed of components playing an apparently passive role: water in the brain and dark energy in the observable Universe.” Understanding Brain Health via Cosmological Health, and vice versa
#2. One very smart and generous brain to brighten your day: Indian teacher Ranjitsinh Disale wins annual $1M Global Teacher Prize; shares half with 9 finalists
#3. “Of all the qualities parents can cultivate in their children, hope and optimism are the most precious. We can nurture hope and optimism in our kids by demonstrating that we always have some control over our environment and ourselves. The future isn’t a tide that’s going to crush us, it’s a wave we’re a part of.” — Madeline Levine, author of Ready or Not. Three favorite 2020 books on parenting and mental health
#5. This survey of 2500 families about what ADHD treatments seem to work/ not work finds that 49% of parents report Exercise to be ‘Extremely or Very Effective;’ above any other treatment.
#6. On the dangers of “productizing” lifestyle guidelines that help build brain reserve and delay cognitive problems; Buyer beware: The story of a pricey and “credentialled” program to end Alzheimer’s Disease
#7. Now, given that “In a new McKinsey report, 62% of employees consider mental health issues a top challenge,” it is good to see growing resources and approaches aimed at addressing the challenge: Calm raises $75 million, expands into corporate mental health and wellness
#8. And, step by step, digital therapeutics are going mainstream: Click Therapeutics raises $30 million in debt to advance commercialization of smoking cessation app Clickotine
#9. Never two without three: Pear Therapeutics raises $80M; finds cost savings of $2,150 per patient with opioid use disorder
#10. Finally, we asked our team and trusted advisors to compile a list of ideas to stay sane and healthy in the months ahead, prioritizing habits shown to promote brain health, resilience and positive neuroplasticity: Enjoy these 3 New Year Resolutions and 36 Ideas for a Happier & Healthier 2021
Wishing you a safe, healthy and happy New Year
Click Therapeutics, Inc. (“Click”), a leader in Digital Therapeutics™ solutions as prescription medical treatments, today announced $30 million in debt financing from K2 HealthVentures (K2HV), a healthcare-focused specialty finance company, to accelerate commercialization of its leading smoking cessation solution, Clickotine™, and to advance its pipeline of clinically-validated digital therapeutics [Read more…] about Click Therapeutics raises $30 million in debt to advance commercialization of smoking cessation app Clickotine
Welcome to a new edition of SharpBrains’ e‑newsletter, featuring 13 fascinating brain research findings, useful resources–and a brain teaser to test your attention skills.
#1. Good news of the month: Elders today are in significantly better shape–physically and cognitively–than three decades ago
#2. A distinction WITH a difference: Actual, sustained practice–not mere knowledge–is needed to harness neuroplasticity and improve cognition over time
#3. “Be mindful that with the rapid changes we are experiencing, our brains are going through accelerated learning. Our brains get tired just as our bodies would if we ran a marathon without training.” How COVID-related stress can disrupt your brain circuits and nine tips to prevent it
#6. Which is why we look forward to seeing 9,000+ students, plus their many teachers and administrators, further develop their unique brains and minds in years ahead: Helping shape the future of lifelong learning via SEK Education Group
#7. “… it would certainly be premature to suggest that moving to a high altitude state would improve a child’s ADHD symptoms. However, the findings highlight the value of keeping an open mind in efforts to understand the development of ADHD and the role natural environments may play in potentially alleviating it.” Study finds surprising correlation between states’ elevation and ADHD prevalence
#9. Time to start paying serious attention to the brain/ cognitive side effects of common medications. Anticholinergic drugs found to significantly increase risk of cognitive decline, especially among those with Alzheimer’s Disease biomarkers or genetic predisposition
#10. Fascinating: “After a 14-day training period … visuospatial skills improved by 40%. This increase in visuospatial ability was shown to be directly responsible for a reduction in motion sickness by 51% in the simulator … and a 58% reduction in the on-road trial.” Study: Self-driving cars will increase motion sickness…unless we retrain our brains to improve visuospatial skills
#11. Behavioral health and neuroplasticity meet big pharma to hopefully address a huge need. Click Therapeutics and Boehringer Ingelheim partner to develop and market a digital therapeutic to treat schizophrenia
#12. Neuralink: Thumbs up or down?
#13. Brain teaser: Did you notice the numerical error as it happened? If not, feel free to go back and find it now 🙂
Wishing you a safe and healthy October,
Alvaro Fernandez and the SharpBrains Team
International pharma Boehringer Ingelheim and prescription digital therapeutics company Click Therapeutics have inked a $500 million-plus deal to jointly develop and commercialize a digital treatment for patients with schizophrenia. [Read more…] about Click Therapeutics and Boehringer Ingelheim partner to develop and market a digital therapeutic to treat schizophrenia
“Developing drugs to treat disorders of the central nervous system is famously fraught with difficulty. Several companies, including Pear Therapeutics and Dthera, are taking a wildly different approach: digital therapeutics. These are pieces of software designed to treat disease that are regulated, prescribed and even paid for as if they were drugs … Pear is so far the only company to have brought a digital therapeutic to market – but it is by no means the only company in this space. Akili Interactive hasfiled for FDA approval of AKL-T01, a computer game designed to treat ADHD, and [Read more…] about Trend: Pharma industry warming up to digital therapeutics