Six guidelines to navigate the Aduhelm controversy and (hopefully) help patients with Mild Cognitive Impairment and early-stage Alzheimer’s Disease

The approval of a con­tro­ver­sial new drug for Alzheimer’s dis­ease, Aduhelm, is shin­ing a spot­light on mild cog­ni­tive impair­ment — prob­lems with mem­o­ry, atten­tion, lan­guage or oth­er cog­ni­tive tasks that exceed changes expect­ed with nor­mal aging. After ini­tial­ly indi­cat­ing that Aduhelm could be pre­scribed to any­one with demen­tia, the Food and Drug Admin­is­tra­tion now spec­i­fies that…

Read More

Study shows why children with ADHD should be reevaluated each year: Attention problems perceived by teachers are far less stable than we imagine

— While the study below was pub­lished a few years ago, it makes an impor­tant point that I think is worth revis­it­ing. In the study, pub­lished in the Jour­nal of Devel­op­men­tal and Behav­ioral Pedi­atrics, my col­leagues and I looked at how fre­quent­ly teacher rat­ings of inat­ten­tive symp­toms per­sist in chil­dren from one grade to the…

Read More

Working Memory Training can Influence Brain Biochemistry

I want­ed to alert you to a very inter­est­ing find­ing pub­lished in a recent issue of Sci­ence, one of the world’s lead­ing sci­en­tif­ic jour­nals. The study was led by Dr. Torkel Kling­berg and his col­leagues from the Karolin­s­ka Insti­tute in Swe­den. The goal was to learn whether Work­ing Mem­o­ry Train­ing is asso­ci­at­ed with changes in…

Read More

Physical and Mental Exercise: Why Pitch One Against the other?

Read­er There­sa Cerul­li just for­ward­ed this Let­ter to the Edi­tor that she had sent to the New York Times and went unpub­lished. The let­ter address­es the OpEd men­tioned here (pitch­ing phys­i­cal vs. men­tal exer­cise), and refers to the Cogmed work­ing mem­o­ry train­ing pro­gram, whose results have been stud­ied in mul­ti­ple papers pub­lished in top medical…

Read More