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Study: 46.7 million Americans have Alzheimer’s Disease brain pathology today, so it’s urgent to prevent or at least delay progression to clinical disease

– In the Alzheimer’s affect­ed brain, abnor­mal lev­els of the beta-amy­loid pro­tein clump togeth­er to form plaques (seen in brown) that col­lect between neu­rons and dis­rupt cell func­tion. Abnor­mal col­lec­tions of the tau pro­tein accu­mu­late and form tan­gles (seen in blue) with­in neu­rons, harm­ing synap­tic com­mu­ni­ca­tion between nerve cells. Source: NIA

New fore­cast shows 6 mil­lion with Alzheimer’s dis­ease, cog­ni­tive impair­ment; The num­bers will more than dou­ble to 15 mil­lion by 2060 (NIH news):

Using new method­ol­o­gy, sci­en­tists cal­cu­late that approx­i­mate­ly 6 mil­lion Amer­i­can adults have Alzheimer’s dis­ease or mild cog­ni­tive impair­ment, which can some­times be a pre­cur­sor to the dis­ease. The esti­mate, fund­ed by the Nation­al Insti­tutes of Health, also fore­casts that these num­bers will more than dou­ble to 15 mil­lion by 2060, as the pop­u­la­tion ages Read the rest of this entry »

Bill Gates announces $50 million investment to fight Alzheimer’s Disease

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Why I’m Dig­ging Deep Into Alzheimer’s (Bill Gates):

In every part of the world, peo­ple are liv­ing longer than they used to. Thanks to sci­en­tif­ic advance­ments, few­er peo­ple die young from heart dis­ease, can­cer, and infec­tious dis­eases. It’s no longer unusu­al for a per­son to live well into their 80s and beyond. My dad will cel­e­brate his 92nd birth­day in a cou­ple weeks, a mile­stone that was prac­ti­cal­ly unimag­in­able when he was born.

This fact—that peo­ple are liv­ing longer than ever before—should always be a won­der­ful thing. But what hap­pens when it’s not? Read the rest of this entry »

Update: 35% of worldwide dementia cases could be prevented by modifying these 9 modifiable risk factors

Time for Sharp­Brains’ July e-newslet­ter, fea­tur­ing fas­ci­nat­ing sci­en­tif­ic find­ings, emerg­ing brain health prac­tices and insights…and some fun teasers.

New research

Let’s start with the key take-aways from a new and very insight­ful evi­dence review which found nine mod­i­fi­able risk fac­tors for demen­tia — account­ing for 35% of all cas­es:
— Edu­ca­tion by age 15 (dur­ing ear­ly life)
— Hyper­ten­sion; Obe­si­ty; Hear­ing loss (in mid-life)
— Depres­sion; Dia­betes; Phys­i­cal inac­tiv­i­ty; Smok­ing; Low social con­tact (in lat­er life)

New thinking

Upcoming events

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Final­ly, you may want to Test your Brain and Mind with these 9 Clas­sic Opti­cal Illu­sions 🙂

 

Have a great August!

The Sharp­Brains Team

Report: 35% of worldwide dementia cases could be prevented by modifying these 9 modifiable risk factors

The Lancet Com­mis­sion: One Third of Demen­tia May Be Pre­ventable (Lancet report release):

Today’s find­ings are extreme­ly hope­ful,” said Maria Car­ril­lo, PhD, chief sci­ence offi­cer at the Alzheimer’s Asso­ci­a­tion. “At an indi­vid­ual lev­el, many peo­ple have the poten­tial to reduce their risk of cog­ni­tive decline, and per­haps demen­tia, through sim­ple, health­ful behav­ior changes. At a pub­lic health lev­el, inter­ven­tions based on this evi­dence could be extreme­ly pow­er­ful in man­ag­ing the glob­al human and eco­nom­ic costs of Alzheimer’s dis­ease and oth­er demen­tias.” Read the rest of this entry »

New studies reinforce Education and Cognitive Reserve –instead of drugs targeting beta amyloid– as most promising avenue to prolong cognitive health and reduce dementia risk

dementia-progressionDemen­tia Risk Declines, And Edu­ca­tion May Be One Rea­son Why (NPR):

Some encour­ag­ing news in the bat­tle against Alzheimer’s dis­ease and oth­er forms of demen­tia: The rate at which old­er Amer­i­cans are get­ting these con­di­tions is declin­ing. That’s accord­ing to Read the rest of this entry »

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