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Neuroplasticity, Brain Fitness and Cognitive Health News

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Must-read interview with George Rebok, PhD: Can cognitive training help aging brains?

george_rebokCan Train­ing Help Aging Brains? (Web­MD):

George Rebok, PhD, con­duct­ed one of the largest stud­ies to date look­ing at how cog­ni­tive train­ing affects old­er adults. Rebok, a pro­fes­sor at the Cen­ter on Aging and Health at Johns Hop­kins School of Pub­lic Health, talks about the study find­ings, com­mer­cial­ly avail­able brain train­ing, and what he rec­om­mends for brain health.

What we found was I think very encour­ag­ing and also some­what sur­pris­ing Read the rest of this entry »

Cognitive therapy or medication? Brain scans may help personalize treatments

Pre­dict­ing How Patients Respond to Ther­a­py (press release):

A new study led by MIT neu­ro­sci­en­tists has found that brain scans of patients with social anx­i­ety dis­or­der can help pre­dict whether they will ben­e­fit from cog­ni­tive behav­ioral therapy…Social anx­i­ety is usu­al­ly treat­ed with either cog­ni­tive behav­ioral ther­a­py or med­ica­tions. How­ev­er, Read the rest of this entry »

Working with Healthcare Stakeholders towards Brain-Based Personalized Medicine

(Edi­tor’s Note: this is Part 3 of the new 3‑part series writ­ten by Dr. Evian Gor­don draw­ing from his par­tic­i­pa­tion at the Per­son­al­ized Med­i­cine World Con­gress on Jan­u­ary, 23, 2012 at Stan­ford Uni­ver­si­ty.)

Work­ing with Health Care Indus­try Stake­hold­ers: Clin­i­cians, Pharma/Biotech, Pay­ers, PBMs, Lawyers, Medicare, FDA

Clin­i­cians seek clear val­i­dat­ed “rules of thumb” that can be eas­i­ly imple­ment­ed and fit into their work­flow and reim­burse­ment regime. Many are explor­ing “Clin­i­cal Deci­sion Sup­port (CDS)” tools on the web and solu­tions linked to “Elec­tron­ic Health Records” (EHR’s). CDC and EHR’s are seed­ing the ground for clin­i­cians to adopt robust Bio­mark­ers that are shown to be unam­bigu­ous­ly clin­i­cal­ly rel­e­vant.

Read the rest of this entry »

Personalized Medicine in Psychiatry: from DSM to brain-based RDoC, iSPOT‑D and biomarkers

(Edi­tor’s Note: this is Part 2 of the new 3‑part series writ­ten by Dr. Evian Gor­don draw­ing from his par­tic­i­pa­tion at the Per­son­al­ized Med­i­cine World Con­gress on Jan­u­ary, 23, 2012 at Stan­ford Uni­ver­si­ty.)

Most Per­son­al­ized Med­i­cine research in Psy­chi­a­try using mol­e­c­u­lar mea­sures alone have failed to repli­cate. Whilst dis­ap­point­ing, this is not sur­pris­ing, since 80% of human 25,000 genes have some effect on the brain.

There are there­fore grow­ing efforts expand­ing Genom­ic Bio­mark­ers in Psy­chi­a­try to Neu­roimag­ing (all Brain-based bio­log­i­cal and cog­ni­tive mea­sures). Some approach­es tar­get Read the rest of this entry »

The State of Personalized Medicine: The Role of Biomarkers

(Edi­tor’s Note: this is Part 1 of the new 3‑part series writ­ten by Dr. Evian Gor­don draw­ing from his par­tic­i­pa­tion at the Per­son­al­ized Med­i­cine World Con­gress on Jan­u­ary, 23, 2012 at Stan­ford Uni­ver­si­ty.)

On aver­age, the med­ica­tions pre­scribed for brain-relat­ed con­di­tions ben­e­fit approx­i­mate­ly 50% of patients. But which 50%?

Per­son­al­ized Med­i­cine seeks to move away from the cur­rent “1 size fits all, tri­al and error” approach that has been nec­es­sary because of a lack of evi­dence. Instead, it focus­es on Read the rest of this entry »

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