Should doctors prescribe Leqembi (lecanemab) to women with early Alzheimer’s Disease? The evidence-based answer is probably No

Wel­come to a new edi­tion of Sharp­Brains e‑newsletter, fea­tur­ing this time a range of inter­ven­tions for brain/ cognitive/ men­tal health plus a few brain teasers to test our per­cep­tion and cog­ni­tive skills. #1. Should doc­tors pre­scribe lecanemab (Leqem­bi) to women? The answer, giv­en avail­able evi­dence, is prob­a­bly No Huge (and most­ly over­looked) red flag regard­ing newly…

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Fully-automated analysis of voice recordings–from neuropsychological tests–found to help differentiate normal cognition from dementia and mild cognitive impairment

Voice Record­ings Spot Cog­ni­tive Impair­ment (Med­Page Today): A machine-learn­ing mod­el iden­ti­fied mild cog­ni­tive impair­ment and demen­tia from dig­i­tal voice record­ings of neu­ropsy­cho­log­i­cal tests, an ear­ly study showed. Among 1,084 peo­ple in the Fram­ing­ham Heart Study whose tests were record­ed, the aver­age area under the curve (AUC) reached 92.6% for dif­fer­en­ti­at­ing nor­mal cog­ni­tion from demen­tia, 88.0% for…

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Geisinger and Eisai to test real-world validity of AI-powered Passive Digital Marker (PDM) in detecting early cognitive impairment and dementia

Research col­lab­o­ra­tion will test nov­el algorithm’s effec­tive­ness on Geisinger data (press release): Geisinger and Eisai Inc. today announced a col­lab­o­ra­tive effort to study the poten­tial effec­tive­ness of an arti­fi­cial intel­li­gence (AI) tool in the detec­tion of cog­ni­tive impair­ment that could iden­ti­fy demen­tias, includ­ing Alzheimer’s dis­ease (AD). If effec­tive, the AI tool could poten­tial­ly be developed…

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Could I be wrong? Exploring cognitive bias, curiosity, intellectual humility, and lifelong learning

Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing eight time­ly sci­en­tif­ic and indus­try news plus a few fun teasers to appre­ci­ate our unique human brains. #1. Could I be wrong? Explor­ing research on cog­ni­tive bias, curios­i­ty, intel­lec­tu­al humil­i­ty, and life­long learn­ing “None of us thinks that our beliefs and atti­tudes are incor­rect; if we…

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Beacon Biosignals raises $27M to scale EEG, AI-based neurobiomarker discovery platform

Neu­rotech start­up Bea­con Biosig­nals scores $27M to bring AI to EEG analy­sis (Med­C­i­ty News): Elec­troen­cephalog­ra­phy is a decades-old tech­nique for cap­tur­ing brain activ­i­ty, data that are used to eval­u­ate brain dis­or­ders. Bea­con Biosig­nals is apply­ing arti­fi­cial intel­li­gence to these tests, and the neu­rotech­nol­o­gy start­up has found a ready mar­ket in phar­ma­ceu­ti­cal com­pa­nies inter­est­ed in assess­ing how…

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Cumulus Neuroscience raises $8.3M to develop EEG-based wireless ‘Fitbit for the brain’

Belfast-based Cumu­lus rais­es €6.9m for its ‘Fit­bit for the brain’ (The Irish Times): … For­mer­ly known as Brain­Wave­Bank, the com­pa­ny has devel­oped a wire­less elec­troen­cephalo­gram (EEG) head­set and pro­pri­etary soft­ware plat­form that use advanced ana­lyt­ics and machine learn­ing to mea­sure cog­ni­tive fit­ness. “This fund­ing will allow us to build on the ground-break­ing advances we have made…

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