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Study finds psychiatric diagnoses to be ‘scientifically meaningless’

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Psy­chi­atric diag­no­sis ‘sci­en­tif­i­cal­ly mean­ing­less’ (Sci­ence Dai­ly):

A new study, pub­lished in Psy­chi­a­try Research, has con­clud­ed that psy­chi­atric diag­noses are sci­en­tif­i­cal­ly worth­less as tools to iden­ti­fy dis­crete men­tal health dis­or­ders.

The study, led by researchers from the Uni­ver­si­ty of Liv­er­pool, involved a detailed analy­sis of five key chap­ters of the lat­est edi­tion of the wide­ly used Diag­nos­tic and Sta­tis­ti­cal Man­u­al (DSM), on ‘schiz­o­phre­nia’, ‘bipo­lar dis­or­der’, ‘depres­sive dis­or­ders’, ‘anx­i­ety dis­or­ders’ and ‘trau­ma-relat­ed dis­or­ders’ Read the rest of this entry »

Time to revamp psychiatry and mental health in light of modern neuroscience?

mentalhealthpuzzleTrans­form­ing Diag­no­sis (arti­cle by Thomas Insel, Direc­tor of the NIMH): “In a few weeks, the Amer­i­can Psy­chi­atric Asso­ci­a­tion will release its new edi­tion of the Diag­nos­tic and Sta­tis­ti­cal Man­u­al of Men­tal Dis­or­ders (DSM‑5)…While DSM has been described as a “Bible” for the field, it is, at best, a dic­tio­nary, cre­at­ing Read the rest of this entry »

Personalized Medicine in Psychiatry: from DSM to brain-based RDoC, iSPOT‑D and biomarkers

(Edi­tor’s Note: this is Part 2 of the new 3‑part series writ­ten by Dr. Evian Gor­don draw­ing from his par­tic­i­pa­tion at the Per­son­al­ized Med­i­cine World Con­gress on Jan­u­ary, 23, 2012 at Stan­ford Uni­ver­si­ty.)

Most Per­son­al­ized Med­i­cine research in Psy­chi­a­try using mol­e­c­u­lar mea­sures alone have failed to repli­cate. Whilst dis­ap­point­ing, this is not sur­pris­ing, since 80% of human 25,000 genes have some effect on the brain.

There are there­fore grow­ing efforts expand­ing Genom­ic Bio­mark­ers in Psy­chi­a­try to Neu­roimag­ing (all Brain-based bio­log­i­cal and cog­ni­tive mea­sures). Some approach­es tar­get Read the rest of this entry »

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