If you fol­lowed lat­est head­lines sur­round­ing the release of the National Alzheimer’s Plan, you’d prob­a­bly con­clude that the likely solu­tion to main­tain life­long brain health is sim­ple: sim­ply wait until 2025 for a “magic bul­let” to be dis­cov­ered, to cure (or end or pre­vent) Alzheimer’s dis­ease and aging asso­ci­ated cog­ni­tive decline. These kinds of beliefs, often rein­forced by doc­tors and adver­tis­ing, may explain the bil­lions spent today by pharma com­pa­nies on dis­cov­er­ing new com­pounds, and by con­sumers on sup­ple­ments like ginkgo biloba. But Read the rest of this entry »

Build­ing Blocks for a Bet­ter Future

The best alter­na­tive for tomor­row should be bet­ter than the best alter­na­tive avail­able today. How do we get there, when “cog­ni­tion” and “brain fit­ness” remain elu­sive con­cepts in pop­u­lar cul­ture? I believe that the lack of pub­lic edu­ca­tion is the major obsta­cle that lim­its the brain fit­ness field’s poten­tial to deliver real-world ben­e­fits, since only informed demand will ensure the ongo­ing devel­op­ment of ratio­nal, struc­tured “rules of the road.” What could be done to address this and other par­tic­u­lar obsta­cles? Read the rest of this entry »

Engag­ing peo­ple where they are in the life-course

Eighty per­cent of the 38,000 adults over age 50 who were respon­ders in the 2010 AARP Mem­ber Opin­ion Sur­vey indi­cated “stay­ing men­tally sharp” was their top ranked inter­est and con­cern (Dinger, 2010). What exactly does this phrase mean? And what role can tech­nol­ogy play in “stay­ing men­tally sharp”? Intel CEO Paul Otellini has said, “You have to start by think­ing about what peo­ple want to do… and work back­ward.” Read the rest of this entry »

(Editor’s Note: This is an excerpt from David DiSalvo’s new book What makes  your brain happy and why you should do the oppo­site.)

Tak­ing a posi­tion in any argument—large or small—is slip­pery busi­ness for our brains. We can have every inten­tion of hon­estly pur­su­ing an answer, yet still fool our­selves into think­ing our method is objec­tive when it is, in fact, any­thing but. Cog­ni­tive sci­ence has helped deci­pher this enigma with research on the the­o­ret­i­cal men­tal struc­tures our brains use to orga­nize infor­ma­tion, called schemata. Read the rest of this entry »

Dr. Michael Merzenich, Emer­i­tus Pro­fes­sor at UCSF, is a lead­ing pio­neer in brain plas­tic­ity research. In the late 1980s, Dr. Merzenich was on the team that invented the cochlear implant. In 1996, he was the found­ing CEO of Sci­en­tific Learn­ing Cor­po­ra­tion (Nas­daq: SCIL), and in 2004 became co-founder and Chief Sci­en­tific Offi­cer of Posit Sci­ence. He was elected to the National Acad­emy of Sci­ences in 1999 and to the Insti­tute of Med­i­cine this year. He retired as Fran­cis A. Sooy Pro­fes­sor and Co-Director of the Keck Cen­ter for Inte­gra­tive Neu­ro­science at the Uni­ver­sity of Cal­i­for­nia at San Fran­cisco in 2007. You may have learned about his work in one of PBS TV spe­cials, mul­ti­ple media appear­ances, or neuroplasticity-related books.

(Alvaro Fer­nan­dez) Dear Michael, thank you very much for agree­ing to par­tic­i­pate in the inau­gural Sharp­Brains Sum­mit in Jan­u­ary, and for your time today. In order to con­tex­tu­al­ize the Summit’s main themes, I would like to focus this inter­view on the likely big-picture impli­ca­tions dur­ing the next 5 years of your work and that of other neu­ro­plas­tic­ity research and indus­try pioneers.

Thank you for invit­ing me. I believe the Sharp­Brains Sum­mit will be very use­ful and stim­u­lat­ing, you are gath­er­ing an impres­sive group together. I am look­ing for­ward to January.

Neuroplasticity-based Tools: The New Health & Well­ness Frontier

There are many dif­fer­ent technology-free approaches to har­ness­ing –enabling, dri­ving– neu­ro­plas­tic­ity. What is the unique value that tech­nol­ogy brings to the cog­ni­tive health table?

It’s all about effi­ciency, scal­a­bil­ity, per­son­al­iza­tion, and assured effec­tive­ness. Tech­nol­ogy sup­ports the imple­men­ta­tion of near-optimally-efficient brain-training strate­gies. Through the Inter­net, it enables the low-cost dis­tri­b­u­tion of these new tools, any­where out in the world. Tech­nol­ogy also enables the per­son­al­iza­tion of brain health train­ing, by pro­vid­ing sim­ple ways to mea­sure and address indi­vid­ual needs in each person’s brain-health train­ing expe­ri­ence. It enables assess­ments of your abil­i­ties that can affirm that your own brain health issues have been effec­tively addressed.

Of course sub­stan­tial gains could also be achieved by orga­niz­ing your every­day activ­i­ties that grow your neu­ro­log­i­cal abil­i­ties and sus­tain your brain health. Still, if the ordi­nary cit­i­zen is to have any real chance of main­tain­ing their brain fit­ness, they’re going to have to spend con­sid­er­able time at the brain gym!

One espe­cially impor­tant con­tri­bu­tion of tech­nol­ogy is the scal­a­bil­ity that it pro­vides for deliv­er­ing brain fit­ness help out into the world. Think about how effi­cient the drug deliv­ery sys­tem is today. Doc­tors pre­scribe drugs, insur­ance cov­ers them, and there is a drug store in every neigh­bor­hood in almost every city in the world so that every patient has access to them. Once neuroplasticity-based tools and out­comes and stan­dard­ized, we can envi­sion a sim­i­lar sce­nario. And we don’t need all those drug stores, because we have the Internet!

Hav­ing said this, there are obvi­ous obsta­cles. One main one, in my mind, is the lack of under­stand­ing of what these new tools can do. Cog­ni­tive train­ing pro­grams, for exam­ple, seem counter-intuitive to con­sumers and many pro­fes­sion­als “ why would one try to improve speed-of-processing if all one cares about is œmem­ory? A sec­ond obvi­ous prob­lem is to get indi­vid­u­als to buy into the effort required to really change their brains for the bet­ter. That buy-in has been achieved for many indi­vid­u­als as it applies to their phys­i­cal health, but we haven’t got­ten that far yet in edu­cat­ing the aver­age older per­son that brain fit­ness train­ing is an equally effort­ful business!

Tools for Safer Dri­ving: Teens and Adults

Safe dri­ving seems to be one area where the ben­e­fits are more intu­itive, which may explain the sig­nif­i­cant traction.

Yes, we see great poten­tial and inter­est among insur­ers for improv­ing dri­ving safety, both for seniors and teens. Appro­pri­ate cog­ni­tive train­ing can lower at-fault acci­dent rates. You can mea­sure clear ben­e­fits in rel­a­tively short time frames, so it won’t take long for insur­ers to see an eco­nomic ratio­nale to not only offer pro­grams at low cost or for free but to incen­tivize dri­vers to com­plete them. All­state, AAA, State Farm and other insur­ers are begin­ning to real­ize this poten­tial. It is impor­tant to note that typ­i­cal acci­dents among teens and seniors are dif­fer­ent, so that train­ing method­olo­gies will need to be dif­fer­ent for dif­fer­ent high-risk populations.

Yet, most dri­ving safety ini­tia­tives today still focus on edu­cat­ing dri­vers, rather that train­ing them neu­ro­log­i­cally. We mea­sure vision, for exam­ple, but com­pletely ignore atten­tional con­trol abil­i­ties, or a driver’s use­ful field of view. I expect this to change sig­nif­i­cantly over the next few years.

Long-term care and health insur­ance com­pa­nies will ulti­mately see sim­i­lar ben­e­fits, and we believe that they will fol­low a sim­i­lar course of action to reduce gen­eral med­ical and neu­rode­gen­er­a­tive dis­ease– (Mild Cog­ni­tive Impair­ment and Alzheimer’s– and Parkinsons-) related costs. In fact, many senior liv­ing com­mu­ni­ties are among the pio­neers in this field.

Boomers & Beyond: Main­tain­ing Cog­ni­tive Vitality

Main­stream media is cov­er­ing this emerg­ing cat­e­gory with thou­sands of sto­ries. But most cov­er­age seems still focused on does it work? more than “how do we define It”, what does work mean? or work for whom, and for what? Can you sum­ma­rize what recent research suggests?

We have seen clear pat­terns in the appli­ca­tion of our train­ing pro­grams, some pub­lished (like IMPACT), some unpub­lished, some with healthy adults, and some with peo­ple with mild cog­ni­tive impair­ment or early Alzheimers Dis­ease (AD). What we see in every case: Read the rest of this entry »

Title: The Sharp­Brains Guide to Brain Fit­ness — Prac­ti­cal Advice to Keep Your Brain Sharp

- Two community-based book talks hosted by New York Pub­lic Library and sup­ported by the Ein­stein Aging Study at Albert Ein­stein Col­lege of Medicine.

Descrip­tion: A fit brain? Can you exer­cise your brain and become men­tally fit? Can you con­tinue to learn and increase your brain’s capac­ity at any age? Alvaro Fer­nan­dez, CEO and Co-Founder of Sharp­Brains, says Yes!, and in this pro­gram he will show you how. Based on research com­piled from lead­ing sci­en­tists in fields of Neu­ro­science, Geron­tol­ogy, and Cog­ni­tive Sci­ence, and pre­sented in his book “The Sharp­Brains Guide to Brain Fit­ness”, Alvaro Fer­nan­dez will pro­vide ways to main­tain and improve your cog­ni­tive health.

He will:
– Debunk 10 Myths of Brain Fit­ness
– Exam­ine the 4 Pil­lars of Brain Main­te­nance
– Dis­cuss the dif­fer­ence between Men­tal Exer­cise and Men­tal Activ­ity
– Eval­u­ate Brain Train­ing Soft­ware
– Explore emerg­ing trends

Book and Bio: Alvaro Fer­nan­dez, CEO and Co-Founder of Sharp­Brains, teaches “Sci­ence of Brain Health and Brain Fit­ness” at UC-Berkeley and San Fran­cisco State Uni­ver­sity. He is the co-author of The Sharp­Brains Guide to Brain Fit­ness.

When and where:
> Sep­tem­ber 23rd, 10am, New York Pub­lic Library, Bronx Library Cen­ter. 310 East Kings­bridge Road. (718) 579‑4244. More infor­ma­tion here.

> Sep­tem­ber 25rd, 1pm, New York Pub­lic Library, Stephen Schwarz­man Build­ing Audi­to­rium. Fifth Avenue at 42nd Street. 917-ASK-NYPL (917–275-6975). More infor­ma­tion here.

This is a par­tial list of the lit­er­a­ture we reviewed dur­ing the research phase of our new book, The Sharp­Brains Guide to Brain Fit­ness.  We know many friends of Sharp­Brains are researchers, health­care pro­fes­sion­als, graduate/ Ph.D. stu­dents, who want have direct access to the ref­er­ences (per­haps PubMed should pro­mote itself as a never end­ing source of men­tal stim­u­la­tion?), so here you have this list, orga­nized by rel­e­vant chap­ter. Please note that the list below appears in the book — whose man­u­script we had to close in Jan­u­ary 2009.

Intro­duc­tion

Basak, C. et al. (2008). Can train­ing in a real-time strat­egy video game atten­u­ate cog­ni­tive decline in older adults? Psy­chol­ogy and Aging.
Beg­ley, S. (2007). Train your mind, change your brain: How a new sci­ence reveals our extra­or­di­nary poten­tial to trans­form our­selves. Bal­lan­tine Books.
DeKosky, S. T., et al. (2008). Ginkgo biloba for pre­ven­tion of demen­tia: a ran­dom­ized con­trolled trial. Jour­nal of the Amer­i­can Med­ical Asso­ci­a­tion, 300, 2253–2262.
Doidge, N. (2007). The Brain that changes itself: Sto­ries of per­sonal tri­umph from the fron­tiers of brain sci­ence. Viking Adult.

Chap­ter 1. The Brain and Brain Fit­ness 101

Bunge, S. A., & Wright, S. B. (2007). Neu­rode­vel­op­men­tal changes in work­ing mem­ory and cog­ni­tive con­trol. Cur­rent Opin­ion In Neu­ro­bi­ol­ogy, 17(2), 243–50.
Dama­sio, A. (1995). Descartes error: Emo­tion, rea­son, and the human brain. Pen­guin Press.
David Kolb, D. (1983). Expe­ri­en­tial learn­ing: Expe­ri­ence as the source of learn­ing and devel­op­ment. FT Press.
Dra­gan­ski, B., Gaser, C., Kem­per­mann, G., Kuhn, H. G., Win­kler, J., Buchel, C., & May A. (2006). Tem­po­ral and spa­tial dynam­ics of brain struc­ture changes dur­ing exten­sive learn­ing. The Jour­nal of Neu­ro­science, 261231, 6314–6317.
Gage, F. H., Kem­per­mann, G., & Song, H. (2007). Adult Neu­ro­ge­n­e­sis. Cold Spring Har­bor Lab­o­ra­tory Press, NY.
Gard­ner, H. (1983). Frames of Mind: The the­ory of mul­ti­ple intel­li­gences. New York: Basic Books.
Gaser, C. & Schlaug, G. (2003). Brain struc­tures dif­fer between musi­cians and non-musicians. The Jour­nal of Neu­ro­science, 23, 9240–9245. Read the rest of this entry »