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treat depression

Study: Personalized, closed-loop neuromodulation can (one day) become a “pacemaker for the brain”

October 5, 2021 by SharpBrains

Click image above to watch 2‑minute video explain­ing the study

Treat­ing Severe Depres­sion with On-Demand Brain Stim­u­la­tion (UCSF press release):

UCSF Health physi­cians have suc­cess­ful­ly treat­ed a patient with severe depres­sion by tap­ping into the spe­cif­ic brain cir­cuit involved in depres­sive brain pat­terns and reset­ting them using the equiv­a­lent of a pace­mak­er for the brain.

“This study points the way to a new par­a­digm that is des­per­ate­ly need­ed in psy­chi­a­try,” said Andrew Krys­tal, PhD, pro­fes­sor of psy­chi­a­try and mem­ber of the UCSF Weill Insti­tute for Neu­ro­sciences. “We’ve devel­oped a pre­ci­sion-med­i­cine approach that has suc­cess­ful­ly man­aged our patient’s treat­ment-resis­tant depres­sion by iden­ti­fy­ing and mod­u­lat­ing the cir­cuit in her brain that’s unique­ly asso­ci­at­ed with her symp­toms.” [Read more…] about Study: Per­son­al­ized, closed-loop neu­ro­mod­u­la­tion can (one day) become a “pace­mak­er for the brain”

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: biomarker, brain circuit, brain patterns, brain stimulation, closed-loop therapy, deep-brain-stimulation, neural biomarker, neuromodulation, neuropsychiatric, pacemaker for the brain, precision medicine, psychiatry, severe depression, treat depression, treatment-resistant depression

Update: Four tips to practice good mental hygiene during the coronavirus outbreak

March 25, 2020 by SharpBrains

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Time for a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing this time 14 time­ly news and resources for men­tal health and brain health innovation.

First of all, let’s remain safe, healthy, and cen­tered dur­ing the cur­rent health cri­sis by fol­low­ing these tips pro­vid­ed by the Greater Good Sci­ence Cen­ter at UC Berkeley:

1. Stay calm and focused
2. Pay atten­tion to those doing the right thing
3. Show gratitude
4. Remem­ber our com­mon bonds

1) “Of course, all of these guide­lines don’t sup­plant the impor­tance of prac­tic­ing good hygiene. We need to con­tin­ue to fre­quent­ly wash our hands and avoid touch­ing our faces, so that we can lessen the chance of infect­ing our­selves and oth­ers. But we also should remem­ber our men­tal hygiene—staying calm our­selves, being grate­ful espe­cial­ly to those doing the right thing, and remem­ber­ing our com­mon human­i­ty. In this way, we can help to make the world safer for all of us.” Four tips to prac­tice good men­tal hygiene dur­ing the coro­n­avirus outbreak

2) “Before any­thing else, prepa­ra­tion is the key to success.”
–Alexan­der Gra­ham Bell

Thank­ful­ly, neu­rotech pio­neer Tan Le out­lines sev­er­al areas where we can take a prac­ti­cal approach to address changes already under­way and lay the ground­work for a more seam­less tran­si­tion to a new era. Fast For­ward to 2040: How to pre­pare for the new era in brain enhance­ment that will change the way we think, work, and heal

3) Here’s a beau­ti­ful way to explore the anato­my of brain regions and brain func­tions. The Vir­tu­al Brain Web Atlas: How the Mind emerges from the Brain

4) “Before stu­dents decide to slip in their ear­buds, though, they should care­ful­ly con­sid­er both their musi­cal selec­tion and the nature of the task” … because “We found that (1) music gen­er­al­ly impaired com­plex task per­for­mance, (2) com­plex music facil­i­tat­ed sim­ple task per­for­mance, and (3) pref­er­ence for exter­nal stim­u­la­tion mod­er­at­ed these effects. There­fore, the data sug­gest that music’s effects on task per­for­mance depend on the music, the task, and the per­former” Does music facil­i­tate or impair cog­ni­tive task per­for­mance? It depends…

5) Because learn­ing can­not, must not, ever stop: Meet the Top 50 final­ists for the Glob­al Teacher Prize 2020

6) Any plans for the sum­mer? Four ways hik­ing pro­motes cog­ni­tive and emo­tion­al health

7) Har­ness­ing tech to pro­mote social con­nect­ed­ness: Every Wednes­day start­ing today we can join scientist/ entre­pre­neur Rana el Kaliou­by online to dis­cuss her new book! Vir­tu­al book tour to explore the fron­tier of Emo­tion­al Intel­li­gence and Technology

8) On-field or off-field, train­ing goes on: Sports teams find cre­ative ways to cross-train the brain off-field

9) “You Can’t Man­age What You Can’t Mea­sure” has­n’t yet reached pub­lic health … but it will. To screen, or not to screen (for demen­tia), that is still the question

10) Sum­ma­riz­ing a recent study, “children’s sleep should be eval­u­at­ed as part of an ADHD eval­u­a­tion as sleep dif­fi­cul­ties are more com­mon … address­ing sleep issues in chil­dren with ADHD is a fea­si­ble and rel­a­tive­ly low-cost approach that can be a valu­able treat­ment com­po­nent for many chil­dren.” Study: A brief sleep inter­ven­tion can bring mea­sur­able and sus­tained ben­e­fits to chil­dren with ADHD

11) Some may and will dis­agree, but net net this offers a major oppor­tu­ni­ty to har­ness smart­phone use data for good: Ver­i­ly and LivaNo­va accel­er­ate efforts to detect and treat depression

12) Poten­tial big news in the neu­ro­mod­u­la­tion mar­ket; coro­n­avirus or not we all have awe­some brains and will expe­ri­ence brain/ men­tal health needs in the future: Medtron­ic might acquire LivaNova’s neu­ro­mod­u­la­tion business

13) What if “An employ­er wants to reduce the risk of on-the-job dis­abil­i­ty, so it screens appli­cants for neu­ro­log­i­cal mark­ers that they are pre­dis­posed to chron­ic pain and depres­sion…” Let’s antic­i­pate the poten­tial mis­use of neu­ro­log­i­cal data to min­i­mize the risks–and max­i­mize the benefits

14) The first brain teaser/ test here is espe­cial­ly rel­e­vant these days … Sev­en fun brain teasers to hon­or our unique Brains and Minds dur­ing Brain Aware­ness Week 2020

 

Have a good and healthy Spring,

The Sharp­Brains Team

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning, Technology & Innovation Tagged With: adhd, brain, brain health, Brain Teasers, brain-functions, chronic pain, coronavirus outbreak, cross-train the brain, dementia, innovation, Learning, LivaNova, Medtronic, mental health, mental hygiene, music, neurological data, neuromodulation, neurotech, sleep, treat depression, Verily

Could technology help cure depression among older adults? (Short answer: Yes)

May 14, 2018 by SharpBrains

___

Why tech­nol­o­gy — not med­ica­tion — is the future of treat­ing old­er adults with depres­sion (McK­night’s Long-term Care News):

“The go-to treat­ment for many cas­es of depres­sion is medication.

Unfor­tu­nate­ly, this treat­ment option can cause as many issues as the prob­lem it is try­ing to solve. Anti­de­pres­sants can put res­i­dents at greater risk of falls, neg­a­tive health com­pli­ca­tions and oth­er poor con­di­tions. Some stud­ies indi­cate that anti­de­pres­sants may not be effec­tive for most old­er Amer­i­cans. [Read more…] about Could tech­nol­o­gy help cure depres­sion among old­er adults? (Short answer: Yes)

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning, Technology & Innovation Tagged With: antidepressants, Brain-Fitness, cognitive disabilities, cognitive-decline, depression, Education & Lifelong Learning, LeadingAge, medication, memory-loss, older-adults, technology, treat depression

Study finds limited benefits from cognitive bias modification (CBM) training, calls for further research

December 21, 2017 by SharpBrains

Faces along a pos­i­tive-neu­tral to neg­a­tive-neu­tral spec­trum, and a sad face, from Peters et al. (2017)‘s CBM for facial inter­pre­ta­tion train­ing. Cred­it: Uni­ver­si­ty of Bristol

Could cog­ni­tive inter­ven­tions be use­ful in treat­ing depres­sion? (Sci­ence News):

“A new study by exper­i­men­tal psy­chol­o­gists from the Uni­ver­si­ty of Bris­tol has exam­ined whether cog­ni­tive bias mod­i­fi­ca­tion (CBM) for facial inter­pre­ta­tion, a dig­i­tal health inter­ven­tion that changes our per­cep­tion for emo­tion­al expres­sions from neg­a­tive to pos­i­tive, might be use­ful in treat­ing depres­sion. [Read more…] about Study finds lim­it­ed ben­e­fits from cog­ni­tive bias mod­i­fi­ca­tion (CBM) train­ing, calls for fur­ther research

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: biomedical-research, CBM, CBM training, Cognitive Bias Modification, depression, digital health, digital health intervention, Experimental Psychology, facial interpretation, Intervention, mood disorders, negative bias, randomized-controlled trial, stressful, translational research, treat depression

Challenge: How to spur meaningful, targeted & safe adoption of emerging neurotechnologies

September 1, 2015 by SharpBrains

neuroelectrics_capA cap that treats depres­sion? Check the sci­ence before get­ting excit­ed (The Guardian):

“Yes­ter­day, an arti­cle in the Entre­pre­neurs sec­tion of the Guardian pur­port­ed to reveal a “cloth cap that could help treat depres­sion”. This claim has caused some alarm in the neu­ro­science and men­tal health fields, so it’s impor­tant to look a lit­tle more close­ly at what the man­u­fac­tur­ers are actu­al­ly claim­ing. [Read more…] about Chal­lenge: How to spur mean­ing­ful, tar­get­ed & safe adop­tion of emerg­ing neurotechnologies

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: depression, EEG, electroencephalography, Mental-Health, Neuroelectrics, neurological, tDCS, Transcranial-direct-current-stimulation, Transcranial-Magnetic-Stimulation, treat depression

Therapy or antidepressants? Coming soon: Brain activity “fingerprints” to personalize depression treatments

January 9, 2015 by SharpBrains

mental health.

To Treat Depres­sion, Drugs or Ther­a­py? (The New York Times):

“Until recent­ly, many experts thought that your clin­i­cian could lit­er­al­ly pick any anti­de­pres­sant or type of psy­chother­a­py at ran­dom because, with a few clin­i­cal excep­tions, there was lit­tle evi­dence to favor one treat­ment over anoth­er for a giv­en patient [Read more…] about Ther­a­py or anti­de­pres­sants? Com­ing soon: Brain activ­i­ty “fin­ger­prints” to per­son­al­ize depres­sion treatments

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Filed Under: Brain/ Mental Health Tagged With: antidepressant, cognitive behavior therapy, cognitive-control, Decision-making, drugs, emotional self-awareness, insula, Mental-Health, personalized therapy, Psychotherapy, psychotropic drugs, therapy, treat depression

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