Fully-automated analysis of voice recordings–from neuropsychological tests–found to help differentiate normal cognition from dementia and mild cognitive impairment

Voice Record­ings Spot Cog­ni­tive Impair­ment (Med­Page Today): A machine-learn­ing mod­el iden­ti­fied mild cog­ni­tive impair­ment and demen­tia from dig­i­tal voice record­ings of neu­ropsy­cho­log­i­cal tests, an ear­ly study showed. Among 1,084 peo­ple in the Fram­ing­ham Heart Study whose tests were record­ed, the aver­age area under the curve (AUC) reached 92.6% for dif­fer­en­ti­at­ing nor­mal cog­ni­tion from demen­tia, 88.0% for…

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Six guidelines to navigate the Aduhelm controversy and (hopefully) help patients with Mild Cognitive Impairment and early-stage Alzheimer’s Disease

The approval of a con­tro­ver­sial new drug for Alzheimer’s dis­ease, Aduhelm, is shin­ing a spot­light on mild cog­ni­tive impair­ment — prob­lems with mem­o­ry, atten­tion, lan­guage or oth­er cog­ni­tive tasks that exceed changes expect­ed with nor­mal aging. After ini­tial­ly indi­cat­ing that Aduhelm could be pre­scribed to any­one with demen­tia, the Food and Drug Admin­is­tra­tion now spec­i­fies that…

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