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Buyer beware: The story of a pricey and “credentialled” program to end Alzheimer’s Disease

December 22, 2020 by Kaiser Health News

When her hus­band was diag­nosed with ear­ly-stage Alzheimer’s dis­ease in 2015, Eliz­a­beth Pan was dev­as­tat­ed by the lack of options to slow his inevitable decline. But she was encour­aged when she dis­cov­ered the work of a UCLA neu­rol­o­gist, Dr. Dale Bre­desen, who offered a com­pre­hen­sive lifestyle man­age­ment pro­gram to halt or even reverse cog­ni­tive decline in patients like her husband.

[Read more…] about Buy­er beware: The sto­ry of a pricey and “cre­den­tialled” pro­gram to end Alzheimer’s Disease

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Filed Under: Brain/ Mental Health Tagged With: aging, Alzheimer’s Disease, cognitive decline, Dale Bredesen, dementia, end Alzheimer's Disease, nutritional supplements, supplements

Survey of 2500 families finds what ADHD treatments seem to work/ not work as applied in the real world

December 17, 2020 by Dr. David Rabiner

Cred­it: CDC Vital Signs

While care­ful­ly con­trolled clin­i­cal tri­als are essen­tial for estab­lish­ing sci­en­tif­ic sup­port for dif­fer­ent ADHD treat­ments, it is also impor­tant to exam­ine how par­ents feel about the treat­ments they actu­al­ly select for their child.

How par­ents feel about ADHD treat­ments they have tried for their child pro­vides an impor­tant com­ple­ment to pub­lished clin­i­cal tri­als data, and can also help guide par­ents’ treat­ment choic­es. [Read more…] about Sur­vey of 2500 fam­i­lies finds what ADHD treat­ments seem to work/ not work as applied in the real world

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Filed Under: Attention & ADD/ADHD Tagged With: AD/HD-treatments, ADHD coaching, alternative ADHD treatments, behavior-therapy, brain training, cognitive-abilities, diet, exercise, medication, mindfulness-meditation, minerals, Neurofeedback, parents, prescription, prescription medication, supplements, survey, Vitamins

On neurons, lifelong learning, meditation, humility, “empty brain calories” and more

October 30, 2020 by SharpBrains

Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing 12 fas­ci­nat­ing neu­ro­science find­ings and open questions–and the beau­ti­ful image above.

#1. “With this image I want to illus­trate the large advances made in imag­ing meth­ods over the past cen­tu­ry, allow­ing mod­ern neu­ro­sci­en­tists to look at neu­rons in ways that Cajal could have only dreamed of.” – Sil­via Rodriguez-Roza­da, Cen­ter for Mol­e­c­u­lar Neu­ro­bi­ol­o­gy, Ham­burg. Award-win­ning image shows neu­roimag­ing progress in a century

#2. One more rea­son why life­long learn­ing mat­ters: Study: High Cog­ni­tive Reserve (CR) seen to sig­nif­i­cant­ly low­er demen­tia risk even in the pres­ence of high Alzheimer’s Dis­ease (AD) neuropathology

#3. It’s Fri­day; per­fect time to make some fun and healthy week­end plans: How feel­ing awe in nature can spur men­tal well-being and per­son­al growth

#4. Not a bad idea either: On cut­ting “emp­ty brain calo­ries” by read­ing a book instead of social media

#5. “…humil­i­ty helps peo­ple let go of defen­sive­ness, take in infor­ma­tion that chal­lenges their polit­i­cal views, and see the human­i­ty in peo­ple on the oth­er side of the polit­i­cal spec­trum. Though it’s not always easy to embrace—especially for those who wrong­ful­ly equate it with weak­ness or a lack of conviction—humility may be what we des­per­ate­ly need right now in the Unit­ed States.” On per­cep­tion, cog­ni­tive bias and cul­ti­vat­ing humil­i­ty ahead of next week’s vote

#6. “When it feels like the world is crash­ing down around them, giv­ing young peo­ple a moment to feel, express, and receive grat­i­tude can help—and that in itself is some­thing to be grate­ful for.” Study: A com­bined teach­ing + app grat­i­tude pro­gram helps ado­les­cents address anx­i­ety and improve men­tal health

#7. To hon­or ADHD Aware­ness Month, let’s address this most impor­tant ques­tion: What should come first to treat ADHD in chil­dren, behav­ior ther­a­py or stim­u­lant medication?

#8. Debate: Can mind­ful­ness and med­i­ta­tion be harm­ful? Two new stud­ies answer the ques­tion in appar­ent­ly oppo­site but actu­al­ly quite com­ple­men­tary ways.

#9. Study: Over-the-counter “brain enhance­ment” sup­ple­ments in the US found both to a) con­tain mul­ti­ple unap­proved drugs and b) lack some ingre­di­ents list­ed on the label. Your take?

#10. “…new study fund­ed by the Nation­al Insti­tutes of Health that aims to recruit 30,000 vol­un­teers to par­tic­i­pate in a mem­o­ry train­ing study that com­pares mul­ti­ple approach­es to train work­ing mem­o­ry”: Giv­en cog­ni­tive strengths and needs are diverse, what brain train­ing may work best for each per­son and under which conditions?

#11. “Vir­tu­al real­i­ty is a promis­ing skills-based behav­ioral med­i­cine that has been shown to have high patient engage­ment and sat­is­fac­tion,” said Beth Dar­nall, PhD, AppliedVR’s chief sci­ence advi­sor. “How­ev­er, chron­ic pain patients to date have had very lim­it­ed access to it, so we’re excit­ed to con­tin­ue work­ing with the FDA to devel­op our plat­form and get it into the mar­ket faster.” The FDA clears Applied­VR head­set to help treat fibromyal­gia and chron­ic pain

#12. “Hav­ing run a media com­pa­ny in a tough mar­ket with a young, mil­len­ni­al work­force, we wit­nessed first-hand how there was a com­plete lack of invest­ment in help­ing this gen­er­a­tion with their men­tal health in a way that they’re used to: a com­mu­ni­ty prod­uct that is mobile-first and video-led. We want to make the world a hap­pi­er place by mak­ing work­ing on your men­tal health as nor­mal as going to the gym.” — Adnan Ebrahim, co-founder and CEO of Mind­Labs. What will the ‘Pelo­ton for men­tal health’ look like five years from now? And, who will devel­op it?

Wish­ing you a safe and healthy November,

Alvaro Fer­nan­dez and the Sharp­Brains Team

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Filed Under: SharpBrains Monthly eNewsletter Tagged With: awe, behavior-therapy, brain-enhancement, cognitive-bias, FDA, humility, Lifelong-learning, medication, meditation, Memory-Training, mental health, mindfulness, Neurons, neuroscience, supplements, virtual-reality, Working-memory

Study: Some “brain-boosting” supplements sold in the US contain not-approved drugs at supratherapeutic doses, exposing users to unknown side effects

December 2, 2019 by SharpBrains

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Some brain-boost­ing sup­ple­ments con­tain an unap­proved drug that could harm users, study warns (STAT news):

“Promis­ing to lift brain fog or improve mem­o­ry, brain-boost­ing sup­ple­ments have joined sex­u­al-enhance­ment and weight-loss reme­dies in the light­ly reg­u­lat­ed world of dietary sup­ple­ments. These prod­ucts may be sold legal­ly with broad-brush come-ons like these, as long as they don’t make spe­cif­ic claims about treat­ing a dis­ease — or con­tain actu­al drugs.

New research led by Dr. Pieter Cohen of Har­vard Med­ical School doc­u­ments five sup­ple­ment brands for sale in the U.S. that con­tain var­i­ous amounts of pirac­etam [Read more…] about Study: Some “brain-boost­ing” sup­ple­ments sold in the US con­tain not-approved drugs at suprather­a­peu­tic dos­es, expos­ing users to unknown side effects

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Filed Under: Education & Lifelong Learning Tagged With: age, brain fog, brain-boosting, brain-boosting supplements, cognitive--disorders, cognitive-enhancement, dementia, dietary supplements, FDA, kidney function, piracetam, supplements

Limitless evidenceless trend: The growth of nootropic supplements

July 9, 2019 by SharpBrains

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The all-too-under­stand­able urge to buy a bet­ter brain (Vox):

“… unfor­tu­nate­ly, Bradley Coop­er is part­ly to blame for the boom of the edi­ble brain-improve­ment industry.

In 2011, he starred in Lim­it­less, a movie about a man who takes a spe­cial pill and becomes smarter and more capa­ble than any­one else on Earth. I’m jok­ing about the cul­tur­al sig­nif­i­cance of this movie, but I’m also not. It was a wild card and an unex­pect­ed hit, and it main­streamed an idea that had already been tak­ing hold among Sil­i­con Val­ley bio­hack­ers and human opti­miza­tion zealots. [Read more…] about Lim­it­less evi­dence­less trend: The growth of nootrop­ic supplements

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Filed Under: Brain/ Mental Health Tagged With: brain, brain health, Brain-Fitness, brain-improvement, brain-improvement industry, dietary supplements, Limitless, mental-fitness, modafinil, nootropics, supplements

Update: Large study finds that consistent use of ADHD medication may stunt growth by 2 inches (5 centimeters)

March 28, 2018 by SharpBrains

___

Time for Sharp­Brains’ eNewslet­ter, bring­ing you lat­est news around med­ica­tion, brain train­ing, sup­ple­ments, mind-wan­der­ing, dig­i­tal ther­a­peu­tics, wear­ables, and more — and also a few quick brain teasers to wrap-up.

New research:

  • Con­sis­tent use of ADHD med­ica­tion may stunt growth by 2 inch­es, large study finds
  • Mind-wan­der­ing may help enhance cre­ativ­i­ty, job per­for­mance and gen­er­al well-being, stud­ies show
  • The ulti­mate in trans­fer from brain train­ing to real-world out­comes: Reduc­ing the risk of at-fault acci­dents by almost 50%

New thinking:

  • AARP, TINA.org and the Nation­al Con­sumers League join forces to chal­lenge Pre­vagen mem­o­ry improve­ment claims
  • Rein­vent­ing Brain Med­i­cine, phar­ma adopts dig­i­tal ther­a­peu­tics: Evi­dence-based videogames, smart­phone apps, and sensors
  • For­get the Oscars — the Greater Good­ies hon­or ten films that high­light the growth mind­set, resilience, and more

New tools:

  • Next in clin­i­cal prac­tice: Auto­mat­ed real-time detec­tion of seizures via wear­able EMG devices
  • DARPA invests in non­sur­gi­cal neu­rotech­nolo­gies for even­tu­al use in healthy human subjects

 

Final­ly, we have a cou­ple of fun, quick brain teasers for you, and also a selec­tion of arti­cles to cel­e­brate Brain Aware­ness Week 2018.

Have a great spring,

The Sharp­Brains Team

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Filed Under: Attention & ADD/ADHD, Brain/ Mental Health, Education & Lifelong Learning Tagged With: Brain-Training, digital therapeutics, enewsletter, medication, mind-wandering, neurotechnologies, Neurotechnology, supplements, wearables

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