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Update: The placebo effect works even when people know they are taking a placebo

August 27, 2020 by Alvaro Fernandez

Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing 14 research find­ings, resources and tips for brain health … and start­ing with this fas­ci­nat­ing study:

#1. Wow. The place­bo effect works even when peo­ple know they are tak­ing a placebo

#2. Beat­ing Alzheimer’s Dis­ease will require a com­bined physical/ men­tal approach: From the ten fac­tors found to increase AD risk in the most com­pre­hen­sive evi­dence review to date,
  • Five are “neck up:” Low­er edu­ca­tion lev­el, Low­er cog­ni­tive activ­i­ty, Head trau­ma, Repeat­ed episodes of depres­sion, High-lev­els of long-term stress.
  • Five are “neck down:” Hyper­ten­sion in mid-life, Ortho­sta­t­ic hypoten­sion, Dia­betes, High BMI, High lev­els of homo­cys­teine. Sys­tem­at­ic review finds ten lifestyle fac­tors that clear­ly impact the prob­a­bil­i­ty of devel­op­ing Alzheimer’s dis­ease (AD)

#3. “The health­i­est peo­ple are the ones who grow with age and expe­ri­ence; even in times of trou­ble like these.” — Dhar­ma Singh Khal­sa, MD, Pres­i­dent of the Alzheimer’s Research and Pre­ven­tion Foun­da­tion. On Stress, Yoga Med­i­ta­tion, and The Evo­lu­tion Revolution

#4. “Accep­tance that Alzheimer’s dis­ease is a lifestyle dis­ease, lit­tle dif­fer­ent from oth­er age-relat­ed dis­eases, that is the sum of a life­time is the most impor­tant break­through of the decade.” — George Per­ry, PhD, Edi­tor-in-Chief of the Jour­nal of Alzheimer’s Dis­ease. High­er body mass index (BMI) linked to low­er blood sup­ply to the brain in large neu­roimag­ing study

#5. “Atten­tion is a scarce resource. Think about your atten­tion­al focus as the beam of a light. If the light is on an object it can­not be on oth­er objects at the same time with the same inten­si­ty … Although we typ­i­cal­ly have the feel­ing that mul­ti­task­ing saves us time, it is often not the case.” Sim­ple, quick brain teas­er to test the lim­its of multitasking

#6. If it appears to rotate, RT ? Fun opti­cal illu­sion to tease your mind

#7. Every cloud has a sil­ver lin­ing: How and when will the telemed­i­cine surge reach men­tal healthcare?

#8. Not a minute too soon: Mag­el­lan Health is test­ing biofeed­back videogame Might­i­er to help chil­dren bet­ter self-reg­u­late stress

#9. “In a time when emo­tions like stress, anx­i­ety, bore­dom, and anger are hard to avoid, a new study sug­gests that a par­tic­u­lar med­i­ta­tion prac­tice can help us face them.” Study: Med­i­ta­tion prac­tice, both for­mal and infor­mal, helps devel­op equa­nim­i­ty over time

#10. Ever since dis­cov­er­ing Bar­bara Arrow­smith-Young’s life tra­jec­to­ry via Nor­main Doidge’s fan­tas­tic book The Brain That Changes Itself, we have been impressed by her cre­ativ­i­ty, sta­mi­na and courage. Com­ing soon: Vir­tu­al World Tour at the fron­tier of applied neu­ro­plas­tic­i­ty, edu­ca­tion and learn­ing difficulties

#11. “Neur­al sig­nals will be used to devel­op algo­rithms that will help researchers deter­mine the opti­mal brain state under which indi­vid­u­als can receive infor­ma­tion. From there, the team will deter­mine the most effec­tive means of enhanc­ing the sub­jects’ abil­i­ty to intake and process infor­ma­tion. This could range from non-inva­sive neuromodulation—or brain stimulation—techniques to the use of aug­ment­ed real­i­ty to alter per­ceived envi­ron­men­tal con­di­tions.” Air Force announces research plat­form to har­ness closed-loop neu­rotech­nol­o­gy and accel­er­ate learn­ing “on the fly”

#12. Good to hear that “ensur­ing the pri­va­cy and secu­ri­ty of study par­tic­i­pants’ data is a high pri­or­i­ty for both UCLA and Apple. UCLA will process and main­tain study data in a secure envi­ron­ment … UCLA and Apple will ana­lyze the data only after they are cod­ed and stripped of names and oth­er con­tact infor­ma­tion.” UCLA launch­es major men­tal health study col­lect­ing & ana­lyz­ing data from Apple wear­ables to bet­ter under­stand depres­sion and anxiety

#13. Flex­i­bil­i­ty is good except when it isn’t: Study finds how sci­en­tists can reach dif­fer­ent con­clu­sions ana­lyz­ing the same brain scans

#14. “I have so much to accom­plish today that I must med­i­tate for two hours instead of one” — Gand­hi, as quot­ed in Sev­en evi­dence-based rea­sons to start med­i­tat­ing yesterday

Wish­ing you a safe and healthy September,

Alvaro Fer­nan­dez on behalf of the Sharp­Brains Team

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning Tagged With: Alzheimer’s Disease, Apple, attentional focus, Barbara Arrowsmith-Young, brain, brain health, Brain Teasers, brain-teaser, meditation, mental healthcare, neural signals, neuroimaging, neuromodulation, Neurotechnology, non-invasive, optical illusion, placebo, Placebo-Effect, research, Stress, tease your mind, telemedicine, UCLA

Latest brain research, tools and teasers to think outside the mental health status quo box

February 26, 2020 by SharpBrains

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Time for a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing a range of  research find­ings, resources, brain teasers and rid­dles to help trans­late emerg­ing neu­ro­science into real-world appli­ca­tions and improve our col­lec­tive brain & men­tal health.

New thinking:

  • Neu­ro­science tips about grat­i­tude, aging, pain and the brain: An inter­view with Dr. Daniel Levitin
  • What’s nor­mal? When it comes to the brain, it’s hard to say, and that’s why we need to study glob­al neurodiversity
  • Will self-dri­ving vehi­cles lead to a surge of brain training?
  • How to remem­ber what you read: Eight tips to improve read­ing speed and cog­ni­tive ability

New research:

  • To boost your men­tal well-being, sim­ply recall, right now, an act of kindness
  • Machine-learn­ing study finds EEG brain sig­na­tures that pre­dict response to anti­de­pres­sant treatments
  • Study finds com­bined phar­ma + non-phar­ma treat­ment most ben­e­fi­cial to help youth with ADHD address long-term aca­d­e­m­ic difficulties
  • Ambi­tious Inter­na­tion­al Brain Ini­tia­tive (IBI) launched to advance glob­al neu­ro­science research

New tools:

  • Large study finds pos­i­tive yet mixed results from Akili’s dig­i­tal ther­a­peu­tic for kids with ADHD
  • U.S. Army devel­ops nov­el way to ana­lyze brain imag­ing data and shape emerg­ing non-inva­sive neurotechnology
  • Med­i­ta­tion app Head­space rais­es $93 mil­lion to accel­er­ate clin­i­cal val­i­da­tion and geo­graph­ic expansion
  • Dig­i­tal men­tal health tak­ing off in Europe

Fun brain teasers:

  • Train your brain to think out­side the box with these fun riddles
  • Three illu­sions to test your per­cep­tu­al and cog­ni­tive skills
  • Math brain teas­er: Will you fin­ish your the­sis on time?

 

Have a great month of March,

 

The Sharp­Brains Team

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Filed Under: Brain Teasers, Brain/ Mental Health, Education & Lifelong Learning, Technology & Innovation Tagged With: adhd, aging, Akili, brain, brain health, brain signatures, Brain Teasers, brain training, brain-research, cognitive-ability, digital therapeutic, europe, Headspace, mental health, mental health status quo, mental well being, neurodiversity, neuroscience, Neurotechnology, non-invasive, non-invasive neurotechnology, riddles, status quo

Important insights on the growing home use of tDCS brain stimulation: older-than-expected users, positive self-reported results for treatment of depression but negative for self-enhancement, and a couple areas of concern (severe burns, frequency)

January 18, 2018 by Alvaro Fernandez

Dr. Brent Williams is wear­ing a home­made tDCS device while his wife Madge is sport­ing a com­mer­cial mod­el. Pho­to by Kevin Liles/kevindliles.com

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At the 2017 Sharp­Brains Vir­tu­al Sum­mit last month, researcher and sci­ence writer Dr. Anna Wexler dis­cussed some fas­ci­nat­ing insights from her sur­vey of 339 home (or “do-it-your­self”) users of tDCS (tran­scra­nial direct cur­rent stim­u­la­tion) devices.

The sur­vey results have just been pub­lished in the Jour­nal of Cog­ni­tive Enhance­ment (details below), and pro­vide a use­ful win­dow into who pur­chas­es tDCS devices and why, how they use them and what results they see. [Read more…] about Impor­tant insights on the grow­ing home use of tDCS brain stim­u­la­tion: old­er-than-expect­ed users, pos­i­tive self-report­ed results for treat­ment of depres­sion but neg­a­tive for self-enhance­ment, and a cou­ple areas of con­cern (severe burns, frequency)

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: brain-stimulation, Consumer neurotechnology, Direct-to-consumer neuroscience, do it yourself, Neuroethics, non-invasive, tDCS, Transcranial-direct-current-stimulation

Neural Analytics raises $15M to commercialize non-invasive, ultrasound-based, brain health monitoring device

January 8, 2018 by SharpBrains

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Neur­al Ana­lyt­ics, Inc. Rais­es $15 Mil­lion in Series B Financ­ing (press release):

“Neur­al Ana­lyt­ics, Inc., a med­ical device com­pa­ny devel­op­ing and com­mer­cial­iz­ing tech­nol­o­gy to mea­sure, diag­nose, and track brain health, today announced that it has raised $15 mil­lion in Series B financ­ing led by Alpha Edi­son [Read more…] about Neur­al Ana­lyt­ics rais­es $15M to com­mer­cial­ize non-inva­sive, ultra­sound-based, brain health mon­i­tor­ing device

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: Alpha Edison, blood vessels, brain, Brain-health, cerebral vasculature, Department of Defense, FDA, Lucid System, Neural Analytics, non-invasive, Transcranial

Study: Transcranial Direct Current Stimulation (tDCS) can reduce fatigue in patients with Multiple Sclerosis (MS)

October 6, 2017 by SharpBrains

 

Leigh Charvet, PhD and a mem­ber of her research team use the tran­scra­nial direct cur­rent stim­u­la­tion (tDCS) equip­ment. Cred­it: NYU Lan­gone Health

_______________

Tran­scra­nial Direct Cur­rent Stim­u­la­tion Shown to Reduce Fatigue Asso­ci­at­ed with Mul­ti­ple Scle­ro­sis (NYU Lagone Health press release):

“Peo­ple with mul­ti­ple scle­ro­sis (MS) who under­went a non-inva­sive form of elec­tri­cal brain stim­u­la­tion expe­ri­enced sig­nif­i­cant reduc­tions in fatigue, a com­mon and often debil­i­tat­ing symp­tom of the dis­ease [Read more…] about Study: Tran­scra­nial Direct Cur­rent Stim­u­la­tion (tDCS) can reduce fatigue in patients with Mul­ti­ple Scle­ro­sis (MS)

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: brain-stimulation, electrical brain stimulation, fatigue, multiple-sclerosis, non-invasive, over-the-counter, rehabilitation, tDCS, telerehabilitation, tES, Transcranial-direct-current-stimulation

Master the digital toolkit to harness lifelong neuroplasticity

December 2, 2016 by SharpBrains

neuroplasticity-—–

We’re look­ing for­ward to many great ses­sions at the vir­tu­al sum­mit next week…this is one of our favorites, Wednes­day, Decem­ber 7th — Mas­ter the dig­i­tal toolk­it to har­ness life­long neu­ro­plas­tic­i­ty. Four lead­ing pio­neers of applied neu­ro­plas­tic­i­ty will help us nav­i­gate best prac­tices to har­ness most promis­ing non-inva­sive neu­rotech­nolo­gies, such as cog­ni­tive train­ing, mind­ful­ness apps, EEG and virtual/ aug­ment­ed reality.

  • Chair: Lin­da Raines, CEO of the Men­tal Health Asso­ci­a­tion of Maryland
  • Dr. Michael Merzenich, win­ner of the 2016 Kavli Prize in Neuroscience
  • Dr. Jud­son Brew­er, Founder & Research Lead of Clar­i­tas Mindsciences
  • Tan Le, CEO of Emo­tiv
  • Dr. Andrea Seri­no, Head of Neu­ro­science at Mind­Maze

Learn more & Reg­is­ter Here

“I know of no bet­ter resource than the annu­al Sharp­Brains Sum­mit to explore the lat­est and what’s next. Excel­lent dis­cus­sions and over­all event.”  - Dr. Michael P. O’Don­nell,  Edi­tor-In-Chief of the Amer­i­can Jour­nal of Health Promotion

“I was impressed by the for­ward-look­ing yet prac­ti­cal dis­cus­sion about enhanc­ing human per­for­mance.” - Dr. Susan Jew­ell, Pres­i­dent of the Inter­na­tional Space Med­i­cine Consortium

“A great way to gath­er cur­rent infor­ma­tion on brain health from a vari­ety of sources and to make new con­nec­tions” - Dr. Cather­ine Madi­son, Direc­tor of the Ray Dol­by Brain Health Cen­ter at Cal­i­for­nia Pacif­ic Med­ical Center

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning, Technology & Innovation Tagged With: augmented reality, Cognitive-Training, digital, EEG, mindfulness apps, neuroplasticity, neurotechnologies, non-invasive, virtual-reality

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