neurotechnologies

Eye-tracking pioneer Smart Eye acquires MIT spin-off Affectiva to augment driver monitoring systems and more

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Emo­tion-detec­tion soft­ware start-up Affec­ti­va acquired for $73.5M (TechCrunch):

Smart Eye, the pub­licly trad­ed Swedish com­pa­ny that sup­plies dri­ver mon­i­tor­ing sys­tems for a dozen automak­ers, has acquired emo­tion-detec­tion soft­ware start­up Affec­ti­va for $73.5 mil­lion in a cash-and-stock deal. [Read more…] about Eye-track­ing pio­neer Smart Eye acquires MIT spin-off Affec­ti­va to aug­ment dri­ver mon­i­tor­ing sys­tems and more

On building better brains at any age, treating Depression vs. Dementia, emerging neurotechnologies, psychedelics, and more

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Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing eleven new research find­ings and inno­v­a­tive resources for life­long cog­ni­tive and brain health.

#1. Debate: Are depres­sion and demen­tia two sides of the same coin? And, if they are, how to best approach treatment?

#2. Either way, the ear­li­er the bet­ter, but it’s nev­er too late: New book out­lines the five lifestyle pil­lars to “build a bet­ter brain at any age”

#3. “If I were a car­di­ol­o­gist eval­u­at­ing a patient’s chest pain, for instance, I would speak with the patient, but then I would lis­ten to their heart and mea­sure their pulse and blood pres­sure. I might order an elec­tro­car­dio­gram or a car­diac stress test, tools that weren’t avail­able a cen­tu­ry ago. Because I’m a psy­chi­a­trist, how­ev­er, I eval­u­ate patients in pre­cise­ly the same way that my pre­de­ces­sors did in 1920…” Read­ing Our Minds: New book issues strong call to action to mod­ern­ize psychiatry

#4. Very time­ly effort by Well­come in the UK: Com­pre­hen­sive research review iden­ti­fies most promis­ing inter­ven­tions to boost work­place men­tal health

#5. “As we enter the sec­ond year of the pan­dem­ic, so many peo­ple are strug­gling and seek­ing men­tal health sup­port. Wysa is an exam­ple of how tech­nol­o­gy is help­ing mil­lions of peo­ple access every­day men­tal health sup­port and self-care tools with­out being gat­ed by a clin­i­cal diag­no­sis.” — Dr. Pankaj Jeth­wani, Exec­u­tive Vice Pres­i­dent at W Health Ven­tures. Arti­fi­cial Intel­li­gence (AI)-enabled chat­bot Wysa rais­es $5.5M to broad­en access to men­tal health support

#6. Study: Social media and gen­er­al tech engage­ment not found to “fry” teenagers’ brains

#7. Akili Inter­ac­tive Labs rais­es $160M in equi­ty and debt to trans­form cog­ni­tive health­care via pre­scrip­tion videogame treat­ments. A nice way to cel­e­brate Akil­i’s 10th anniver­sary … they are tar­get­ing ADHD first (now kids, lat­er teens and adults), to be fol­lowed by treat­ments for a range of cog­ni­tive dis­or­ders relat­ed to depres­sion, Mul­ti­ple Scle­ro­sis, Autism, “Covid-Fog” and more.

#8. Study: High­er men­tal well­be­ing (in 2016) seen to low­er health­care costs (in 2017). We still have time to invest in pub­lic men­tal well­be­ing in 2021.

#9. Teladoc Health, hav­ing acquired Livon­go and myS­trength, launch­es inte­grat­ed men­tal health ser­vice for the work­place. “The announce­ment comes as more than half of peo­ple with men­tal health con­cerns report that they do not know where to start when get­ting care, high­light­ing the impor­tance of the dig­i­tal front door myS­trength Com­plete will pro­vide…” This is indeed a very com­mon pain point accord­ing to our own research, so good to see the quite com­pre­hen­sive & per­son­al­ized approach.

#10. Cumu­lus Neu­ro­science rais­es $8.3M to devel­op EEG-based wire­less ‘Fit­bit for the brain’ — Fas­ci­nat­ing to see the major role of the Demen­tia Dis­cov­ery Fund, in a bid to accel­er­ate clin­i­cal tri­als and poten­tial therapies.

#11. Last but not least, a very promis­ing clin­i­cal appli­ca­tion of psy­che­delics: Study finds MDMA-assist­ed ther­a­py to be safe and high­ly effec­tive to treat severe PTSD. “The Nature authors spec­u­late that MDMA-assist­ed ses­sions pro­duce a “win­dow of tol­er­ance,” in which patients are able to revis­it trau­mat­ic mem­o­ries, with less shame and anger, and with­out being over­whelmed by PTSD symptoms.”

Wish­ing you a healthy Memo­r­i­al Week­end and month of June,

The Sharp­Brains Team

Reading Our Minds: New book issues strong call to action to modernize psychiatry

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The Rise of Big Data Psy­chi­a­try (The Wall Street Journal):

As a physi­cian, I need to fig­ure out three things when a new patient walks into my office: what their life is typ­i­cal­ly like, what has changed that made them seek treat­ment and what I can do to help them. It’s a com­plex prob­lem, and most fields of med­i­cine approach it by tak­ing mea­sure­ments. If I were a car­di­ol­o­gist eval­u­at­ing a patient’s chest pain, for instance, I would speak with the patient, but then I would lis­ten to their heart and mea­sure their pulse and blood pres­sure. I might order an elec­tro­car­dio­gram or a car­diac stress test, tools that weren’t avail­able a cen­tu­ry ago.

Because I’m a psy­chi­a­trist, how­ev­er, I eval­u­ate patients in pre­cise­ly the same way that my pre­de­ces­sors did in 1920: I ask them to tell me what’s wrong, and while they’re talk­ing I care­ful­ly observe their speech and behav­ior. But psy­chi­a­try has remained large­ly immune to mea­sure­ment. At no point in the exam­i­na­tion do I gath­er numer­i­cal data about the patient’s life or behav­ior, even though tools for tak­ing such mea­sure­ments already exist. In fact, you like­ly are car­ry­ing one around in your pock­et right now. Keep read­ing essay HERE, adapt­ed from the new book Read­ing Our Minds: The Rise of Big Data Psy­chi­a­try by psy­chi­a­trist Daniel Bar­ron. [Read more…] about Read­ing Our Minds: New book issues strong call to action to mod­ern­ize psychiatry

Click Therapeutics raises $30 million in debt to advance commercialization of smoking cessation app Clickotine

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Click Ther­a­peu­tics Secures $30M in Growth Cap­i­tal from K2 HealthVen­tures to Expand Oper­a­tions (press release):

Click Ther­a­peu­tics, Inc. (“Click”), a leader in Dig­i­tal Ther­a­peu­tics™ solu­tions as pre­scrip­tion med­ical treat­ments, today announced $30 mil­lion in debt financ­ing from K2 HealthVen­tures (K2HV), a health­care-focused spe­cial­ty finance com­pa­ny, to accel­er­ate com­mer­cial­iza­tion of its lead­ing smok­ing ces­sa­tion solu­tion, Click­o­tine™, and to advance its pipeline of clin­i­cal­ly-val­i­dat­ed dig­i­tal ther­a­peu­tics [Read more…] about Click Ther­a­peu­tics rais­es $30 mil­lion in debt to advance com­mer­cial­iza­tion of smok­ing ces­sa­tion app Clickotine

Air Force announces research platform to harness closed-loop neurotechnology and accelerate learning “on the fly”

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U.S. Air Force illustration/Richard Eldridge

Air Force Neu­rotech­nol­o­gy Part­ner­ship Aims to Accel­er­ate Learn­ing (Mil­i­tary Spot):

The Indi­vid­u­al­ized Neur­al Learn­ing Sys­tem, or iNeu­raLS, is a new aug­ment­ed learn­ing plat­form that will enable rapid learn­ing by closed-loop mod­u­la­tion of cog­ni­tive states dur­ing skill acqui­si­tion. Essen­tial­ly, the AFRL team seeks to devel­op a capa­bil­i­ty that will give Air­men the abil­i­ty to rapid­ly acquire knowl­edge and skills on the fly through direct brain inter­faces with the help of neurotechnologies…

[Read more…] about Air Force announces research plat­form to har­ness closed-loop neu­rotech­nol­o­gy and accel­er­ate learn­ing “on the fly”

Update: The latest research and noninvasive neurotechnologies for brain health and mental fitness

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Time for a new edi­tion of Sharp­Brains’ e‑newsletter!

1. Food for (non­par­ti­san) Thought: Should heads of state and can­di­dates to high office pass a cognitive/ men­tal fit­ness test?

2. A school psy­chol­o­gist shares good tips to sup­port our kids and, yes, man­age our own stress. Three Ss to reduce the stress of “home­school­ing” our kids: Sim­pli­fy, Struc­ture, Sup­port.

3. Wow. Mind­strong Health rais­es $100M to trans­form how we mea­sure and pro­mote men­tal health.

4. Great part­ner­ship! Kaiser Per­ma­nente offers Calm men­tal fit­ness app at no cost to mil­lions of mem­bers.

5. “Just as you can’t self-intro­spect to deter­mine your cho­les­terol, much of the high­est-val­ue infor­ma­tion about our­selves and each oth­er sits out­side our con­scious aware­ness.” — Bryan John­son, Founder and CEO of Ker­nel, as Ker­nel launch­es Neu­ro­science as a Ser­vice (NaaS) built on non-inva­sive brain record­ing tech­nol­o­gy.

6. Fas­ci­nat­ing con­ver­sa­tion on how and why “Prac­tice actu­al­ly changes the phys­i­cal­i­ty of your brain” — Q&A with Rick Han­son on Neu­rod­har­ma, brain sci­ence, per­son­al prac­tice and well-being

7. May this trend con­tin­ue (and for bet­ter rea­sons): Grow­ing inter­est in dig­i­tal men­tal health among insur­ers and med­ical care providers.

8. Par­tic­u­lar­ly promis­ing for mul­ti­ple scle­ro­sis, ocu­lar hyper­ten­sion, dia­betes, and trau­mat­ic brain injury: Portable brain assess­ment device by Head­safe secures 510(k) FDA clear­ance.

9. May a lim­er­ick a day keep the neu­rol­o­gist away?

10. If not a lim­er­ick, per­haps a few brain teasers. Say the months of the year in alpha­bet­i­cal order. Too easy? Well, try doing so back­wards, in reverse alpha­bet­i­cal order. Five quick brain teasers to flex those Atten­tion and Work­ing Mem­o­ry men­tal muscles

11. You have been invit­ed to a fundrais­ing gala at your old col­lege (via Zoom of course) and decide that this black-tie event demands a super white Ital­ian shirt, like the one you bought years ago for your wed­ding. Ready for some quick math? Try this Brain Teas­er: What shirt size you need?

Have a great month of June,

The Sharp­Brains Team