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Neurogenesis

Study finds lifelong neurogenesis in the hippocampus, but rates decline with age and, especially, Alzheimer’s disease

March 25, 2019 by SharpBrains

Recent, imma­ture neu­rons (in red) and old­er, mature neu­rons (in blue) in the hip­pocam­pus of a 68-year-old’s brain. Cred­it: CSIC

___

Old brains still make neu­rons, study finds, offer­ing a pos­si­ble way to pro­tect against Alzheimer’s (STAT):

“Reports of old brains’ decrepi­tude have been great­ly exag­ger­at­ed, sci­en­tists report­ed on Mon­day, unveil­ing results that con­tra­dict a much-dis­cussed 2018 study and instead sup­port the idea that human gray mat­ter is capa­ble of gen­er­at­ing new neu­rons up to the ninth decade of life.

The research, pub­lished in Nature Med­i­cine, also found that old brains from peo­ple with­out demen­tia have much high­er rates of such neu­ro­ge­n­e­sis than [Read more…] about Study finds life­long neu­ro­ge­n­e­sis in the hip­pocam­pus, but rates decline with age and, espe­cial­ly, Alzheimer’s disease

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning Tagged With: adult hippocampal neurogenesis, age, Alzheimer’s, Alzheimer’s Disease, dementia, hippocampus, Neurogenesis, Neurons

Lifestyle and neurotechnology over genetics

May 31, 2018 by SharpBrains

”

Dear col­league,

It’s remark­able how quick­ly things are chang­ing, final­ly, in brain health and men­tal health — see for exam­ple what’s new with Inter­ax­on, Akili, Neu­raMetrix, Apple, Calm, Halo Neu­ro­science, Mind­strong Health, Novar­tis, Pear Ther­a­peu­tics, and life­long neu­ro­ge­n­e­sis, all in the last 6 months!

Please enjoy the May edi­tion of Sharp­Brains eNewslet­ter below, and con­sid­er join­ing the Sharp­Brains Vir­tu­al Sum­mit this Decem­ber to dis­cuss the lat­est and help shape the next 🙂

New research:

  • Cog­ni­tive train­ing, diet, exer­cise, and vas­cu­lar man­age­ment seen to improve cog­ni­tion even in peo­ple with genet­ic pre­dis­po­si­tion for demen­tia (APOE e4)
  • Brain imag­ing show that patients with Alzheimer’s dis­ease can still remem­ber and enjoy their favorite songs
  • Phys­i­cal exer­cise doesn’t slow down demen­tia once it appears, study shows

New tools:

  • Ini­tial study finds promise and lim­i­ta­tions in using vir­tu­al real­i­ty (VR) to treat ADHD
  • tDCS com­ing to an Equinox gym near you: Good, Bad or Depends?
  • Could tech­nol­o­gy help cure depres­sion among old­er adults? (Short answer: Yes)

New thinking:

  • Six tips for social-emo­tion­al learn­ing (SEL) to trans­fer into real-world skills
  • Large study to assess impact on ear­ly brain devel­op­ment of finan­cial assis­tance to low-income mothers
  • New book high­lights con­tin­ued brain devel­op­ment through­out ado­les­cence, even into our 20s
  • Pre­sen­ta­tion on Neu­ro­science, Edu­ca­tion and Life­long Learn­ing (in Spanish)

 

Have a great month of June,

 

The Sharp­Brains Team

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: Akili, Apple, Brain-health, Brain-Imaging, Calm, Cognitive-Training, dementia, diet, exercise, Genetics, Halo Neuroscience, Interaxon, lifestyle, Mindstrong Health, NeuraMetrix, neuro, Neurogenesis, neurotech, Neurotechnology, Novartis, Pear Therapeutics, tDCS, vascular management, virtual-reality

Update: Study finds continued birth of new neurons (neurogenesis) well into our 70s

April 25, 2018 by SharpBrains

___

Time for Sharp­Brains eNewslet­ter, bring­ing you the lat­est in in brain health and men­tal health research, tools and thinking.

Also, a quick heads-up for those based in the UK: the Impe­r­i­al Col­lege Cen­tre for Neu­rotech­nol­o­gy will host a keynote by Alvaro Fer­nan­dez in Lon­don on Wednes­day, May 30th, titled Why the Future of Brain Enhance­ment & Men­tal Health is Dig­i­tal & Per­va­sive (free; requires reg­is­tra­tion). Oth­er upcom­ing events here.

New research:

  • Study finds con­tin­ued birth of new neu­rons (neu­ro­ge­n­e­sis) well into our 70s
  • The more hours you sit per day, the small­er your medi­al tem­po­ral lobe (MTL) seems to become, brain scans show
  • Study com­bines MRI brain scans with sta­tis­tics to bet­ter pre­dict cog­ni­tive prob­lems after stroke

New tools:

  • Med­i­ta­tion app Calm said to be rais­ing $25M to become the “Nike of the mind”
  • Mind­strong Health iden­ti­fies dig­i­tal bio­mark­ers of cog­ni­tive func­tion using smart­phone data
  • Wear­able brain scan­ners to enable broad­er, eas­i­er, cheap­er access to neuroimaging

New thinking:

  • Com­bin­ing brain stim­u­la­tion with cog­ni­tive train­ing to enhance atten­tion and memory
  • Evi­dence review finds that com­put­er-based cog­ni­tive train­ing can sig­nif­i­cant­ly improve mem­o­ry in patients with mul­ti­ple scle­ro­sis (MS)
  • Despite grow­ing evi­dence against sup­ple­ments mak­ing brain/ mem­o­ry improve­ment claims, sales keep growing

 

Final­ly, please Save the Date for the sec­ond edi­tion of the Brain­no­va­tions Pitch Con­test on Decem­ber 5th, 2018. Giv­en the suc­cess of the inau­gur­al event last year (details here), the 2018 Sharp­Brains Vir­tu­al Sum­mit will host a sec­ond con­test for 12 star­tups to pitch their inno­v­a­tive solu­tions to all Sum­mit par­tic­i­pants and to dis­tin­guished Judges –our very own “Sharp Tank.”

Have a great month of May,

The Sharp­Brains Team

–- Mem­bers of the Brain­no­va­tions Judg­ing Panel

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: app, brain, Brain-health, brain-scans, brain-stimulation, Brainnovations, cognitive, Cognitive-Training, meditation, Mental-Health, Neurogenesis, Neurotechnology, smartphone

Study finds continued birth of new neurons (neurogenesis) well into our 70s

April 11, 2018 by SharpBrains

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New brain mem­o­ry cells devel­op well into old age (Reuters):

“Well into our 70s, we con­tin­ue to devel­op new cells in an area of the brain respon­si­ble for new mem­o­ries and explo­ration of new envi­ron­ments, sci­en­tists report.

“These new brain cells sus­tain our abil­i­ties to make new mem­o­ries, learn, and cope with the envi­ron­ment, and they are impor­tant for [Read more…] about Study finds con­tin­ued birth of new neu­rons (neu­ro­ge­n­e­sis) well into our 70s

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning Tagged With: angiogenesis, Brain-Fitness, cognitive-fitness, Cognitive-impairment, Neurogenesis, Neurons, neuroplasticity, neuropsychiatric

Ten Suggestions for Brain-friendly New Year’s Resolutions

December 27, 2016 by Alvaro Fernandez

neuroplasticity-brain—–

You are enjoy­ing the shop­ping and hol­i­day sea­son. Great!

Now it’s time to start shift­ing gears and focus on the year ahead…

Let’s review some good lifestyle options we can all fol­low to main­tain, and improve, our sharp brains. Per­haps they will inspire some New Year’s Res­o­lu­tions to help make 2017 a year of Brain Health!

1. Thrive on Learn­ing. The point of hav­ing a brain is to learn and to adapt to chal­leng­ing new envi­ron­ments. Once new neu­rons appear in your brain, where they migrate and how long they sur­vive depends on how you use them. “Use It or Lose It” does not mean “do cross­word puz­zle num­ber 1,234,567.” It means, “chal­lenge your brain, and often, with nov­el activ­i­ties”… for exam­ple, here you have quite a col­lec­tion of brain teasers and games for adults of every age.

2. Remem­ber that the brain is part of the body. Things that exer­cise your body can also help sharp­en your brain: phys­i­cal exer­cise enhances neu­ro­ge­n­e­sis, at any age!

3. Learn more about the “It” in “Use It or Lose It.” A basic under­stand­ing will serve you well to appre­ci­ate your brain’s beau­ty as a liv­ing and con­stant­ly-devel­op­ing dense for­est with bil­lions of neu­rons and synapses.

4. Take care of your nutri­tion. Did you know that the brain only weighs 2% of body mass but con­sumesgood brain food over 20% of the oxy­gen and nutri­ents we intake? As a gen­er­al rule, you don’t need expen­sive ultra-sophis­ti­cat­ed nutri­tion­al sup­ple­ments, just make sure you don’t stuff your­self with the “bad stuff.”

5. Prac­tice pos­i­tive, action-ori­ent­ed thoughts until they become your default mind­set and you look for­ward to cre­at­ing some­thing mind­ful and beau­ti­ful every new day. Too much stress and anxiety–induced by exter­nal events or by your own thoughts–can kill neu­rons and pre­vent the cre­ation of new ones. physical exercise for brain health

6. We are, as far as we know, the only self-direct­ed organ­isms in this plan­et. Aim high. Once you grad­u­ate from col­lege, keep learn­ing. Once you become too com­fort­able in one job, find a new one. The brain keeps devel­op­ing ALWAYS, reflect­ing what you do with it.

7. Explore, trav­el. Adapt­ing to new loca­tions forces you to pay more atten­tion to your envi­ron­ment. Make new deci­sions, use your brain.

8. Don’t Out­source Your Brain. Not to media per­son­al­i­ties, not to politi­cians, not to your smart neigh­bour… Make your own deci­sions, and your own mis­takes. That way, you are train­ing your brain, not your neighbour’s.

9. Devel­op and main­tain stim­u­lat­ing friend­ships. We are social ani­mals, and need social inter­ac­tion. Which, by the way, is why ‘Baby Ein­stein’ or all those edu­ca­tion­al apps have been shown not to be the panacea for chil­dren development.

10. Laugh. Often. Espe­cial­ly to cog­ni­tive­ly com­plex humor, full of twists and surprises. 

SharpBrainsGuide_3DNow, remem­ber that what counts is not read­ing this article–or any oth­er– but prac­tic­ing a bit every day until small steps snow­ball into unstop­pable, inter­nal­ized habits. Please revis­it the sug­ges­tion above that real­ly grabbed your atten­tion, and make a New Year’s Res­o­lu­tion to try some­thing new in 2017.

–> To learn more about what you can do, check out The Sharp­Brains Guide to Brain Fit­ness: How to Opti­mize Brain Health and Per­for­mance at Any Age.

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning Tagged With: brain-friendly, Brain-health, Neurogenesis, New Year's Resolutions

The Nine Habits of Highly Effective Brains

August 18, 2016 by Alvaro Fernandez

sharp brains—————

While we are still (hope­ful­ly) enjoy­ing some down­time, let’s review some good lifestyle options we can all fol­low to not only main­tain, but improve, our vibrant brains. [Read more…] about The Nine Habits of High­ly Effec­tive Brains

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Filed Under: Education & Lifelong Learning Tagged With: brain, brain-development, Brain-Fitness, Brain-health, habits, Neurogenesis, neuroplasticity, sharp brains, smart-brains, wellness

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