Deep learning model built on neuroimaging data identifies “Brain Age Gaps” as markers of Alzheimer’s disease (AD)

Brain Age Gap is a Com­pos­ite Bio­mark­er for Demen­tia Pathol­o­gy or Sever­i­ty (GEN): Mayo Clin­ic sci­en­tists have devel­oped a com­pu­ta­tion­al mod­el that pre­dicts brain age using a large col­lec­tion of neu­roimag­ing data obtained using FDG-PET (flu­o­rodeoxyglu­cose positron emis­sion tomog­ra­phy) and struc­tur­al MRI (mag­net­ic res­o­nance imag­ing). The deep learn­ing-based mod­el tests the rela­tion­ship between brain age…

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September 17th @ UC Berkeley: Disrupting neurodegenerative diseases

__________ Quick heads-up about a great event next month for those based in the San Fran­cis­co Bay Area. When: Tues­day, Sep­tem­ber 17, 2019 / 8:30 AM – 6:00 PM PDT Where: Pauley Ball­room, UC Berke­ley What: 2019 UC Berke­ley Aging Research & Tech­nol­o­gy Sum­mit: Dis­rupt­ing Neu­rode­gen­er­a­tive Dis­eases Alzheimer’s and neu­rode­gen­er­a­tive dis­eases are

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Study finds promise in smell training to harness neuroplasticity and improve brain health in older adults

___ An impaired sense of smell can sig­nal cog­ni­tive decline, but ‘smell train­ing’ could help (The Con­ver­sa­tion): “As we age, we often have prob­lems with our abil­i­ty to smell (called olfac­to­ry dys­func­tion). Old­er peo­ple might not be able to iden­ti­fy an odour or dif­fer­en­ti­ate one odour from anoth­er. In some cas­es they might not be able…

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Study: Practice effect due to repeated testing can delay detection of cognitive impairment and dementia

___ Prac­tice Imper­fect: Repeat­ed Cog­ni­tive Test­ing Can Obscure Ear­ly Signs of Demen­tia (UC San Diego Health press release): “Alzheimer’s dis­ease (AD) is a pro­gres­sive, neu­rode­gen­er­a­tive con­di­tion that often begins with mild cog­ni­tive impair­ment or MCI, mak­ing ear­ly and repeat­ed assess­ments of cog­ni­tive change cru­cial to diag­no­sis and treat­ment. But in a paper pub­lished online in…

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Bill Gates announces $50 million investment to fight Alzheimer’s Disease

_____ Why I’m Dig­ging Deep Into Alzheimer’s (Bill Gates): “In every part of the world, peo­ple are liv­ing longer than they used to. Thanks to sci­en­tif­ic advance­ments, few­er peo­ple die young from heart dis­ease, can­cer, and infec­tious dis­eases. It’s no longer unusu­al for a per­son to live well into their 80s and beyond. My dad will…

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Augmenting physiotherapy via neurofeedback and neurostimulation: Key neurotechnology patent #43

therapy control

Today we are shar­ing a fas­ci­nat­ing patent from Medtron­ic.  (As men­tioned, we are fea­tur­ing 50 foun­da­tion­al Per­va­sive Neu­rotech patents, from old­er to new­er by issue date) U.S. Patent No. 8,121,694: Ther­a­py con­trol based on a patient move­ment state Assignee(s): Medtron­ic, Inc. Inventor(s): Gre­go­ry F. Mol­nar, Steven S. Gill, Kei­th A, Miesel, Mark S. Lent, Tim­o­thy J. Deni­son, Eric J.…

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