Alto Neuroscience raises $60M (equity + credit) to help fix the “trial and error” approach to psychiatric medication

Alto Neu­ro­science bags $25M for four Phase II drugs (End­points News): Anoth­er $25 mil­lion is flow­ing the way of a Cal­i­for­nia biotech attempt­ing to fix the “tri­al and error” sys­tem in neu­ro­science drug R&D. Alto Neu­ro­science picked up the cap­i­tal from Alpha Wave Ven­tures via an exten­sion to its Series B, bring­ing total equi­ty raised…

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The way we approach Mental Health today is broken beyond repair. The question is, what comes next, and how fast can we get there?

The hid­den links between men­tal dis­or­ders (Nature): In 2018, psy­chi­a­trist Oleguer Plana-Ripoll was wrestling with a puz­zling fact about men­tal dis­or­ders. He knew that many indi­vid­u­als have mul­ti­ple con­di­tions — anx­i­ety and depres­sion, say, or schiz­o­phre­nia and bipo­lar dis­or­der. He want­ed to know how com­mon it was to have more than one diag­no­sis, so he…

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Large study with twins highlights the limited role of genetics in mental health and the importance of effective early interventions for ADHD

___ Mul­ti­ple stud­ies have indi­cat­ed that, on aver­age, youth with ADHD have poor­er out­comes in young adult­hood in mul­ti­ple areas com­pared to their unaf­fect­ed peers. A lim­i­ta­tion of these stud­ies, how­ev­er, is that they have not typ­i­cal­ly dis­tin­guished between indi­vid­u­als whose ADHD per­sists into adult­hood from those where the con­di­tion remits.

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Lifestyle and neurotechnology over genetics

?” Dear col­league, It’s remark­able how quick­ly things are chang­ing, final­ly, in brain health and men­tal health — see for exam­ple what’s new with Inter­ax­on, Akili, Neu­raMetrix, Apple, Calm, Halo Neu­ro­science, Mind­strong Health, Novar­tis, Pear Ther­a­peu­tics, and life­long neu­ro­ge­n­e­sis, all in the last 6 months! Please enjoy the May edi­tion of Sharp­Brains eNewslet­ter below, and con­sid­er join­ing the…

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Question: Do genes determine the fate of our brains?

———- Answer: No, not even close. Thanks to life­long neu­ro­plas­tic­i­ty, our lifestyles are as impor­tant as our genes–if not more–in how our brains grow and our minds evolve. Keep read­ing 20 Must-Know Facts To Har­ness Neu­ro­plas­tic­i­ty And Improve Brain Health over at The Cre­ativ­i­ty Post.

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