Lifestyle Matters: Let’s optimize cognition, health and life in 2024

Wel­come to a new edi­tion of Sharp­Brains e‑newsletter, fea­tur­ing fas­ci­nat­ing research find­ings on lifestyle, pro­tec­tive brain struc­tures, Inter­net access, men­tal health, brain imag­ing, and more. #1. Lifestyle mat­ters: What we can do in 2024 to opti­mize cog­ni­tion and life, delay­ing cog­ni­tive prob­lems even demen­tia “Actor Chris Hemsworth…watched his grand­fa­ther live with Alzheimer’s and is mak­ing lifestyle…

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Study identifies protective brain structure that delays the onset of frontotemporal dementia symptoms over 2 years

Few peo­ple had prob­a­bly heard of fron­totem­po­ral demen­tia until ear­li­er this year, when the fam­i­ly of actor Bruce Willis announced the 68-year-old had been diag­nosed with the con­di­tion. Fron­totem­po­ral demen­tia is a rare dis­ease – thought to account for only one in every 20 cas­es of demen­tia. Symp­toms usu­al­ly devel­op in a person’s late 50s,…

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Deep learning model built on neuroimaging data identifies “Brain Age Gaps” as markers of Alzheimer’s disease (AD)

Brain Age Gap is a Com­pos­ite Bio­mark­er for Demen­tia Pathol­o­gy or Sever­i­ty (GEN): Mayo Clin­ic sci­en­tists have devel­oped a com­pu­ta­tion­al mod­el that pre­dicts brain age using a large col­lec­tion of neu­roimag­ing data obtained using FDG-PET (flu­o­rodeoxyglu­cose positron emis­sion tomog­ra­phy) and struc­tur­al MRI (mag­net­ic res­o­nance imag­ing). The deep learn­ing-based mod­el tests the rela­tion­ship between brain age…

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