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The latest on Brain Health and Resilience, plus a few fun Brain Teasers

November 30, 2020 by SharpBrains

Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing fas­ci­nat­ing neu­ro­science find­ings and tips, com­bined with fun brain teasers.

#1. To cel­e­brate this quite-chal­leng­ing Thanks­giv­ing, here are five fun brain teasers that read­ers have enjoyed the most this year so far. It is always good to learn more about (and appre­ci­ate) that most pre­cious resource we all (yes, all) have up there! Five fun brain teasers to thank evo­lu­tion for our human brains and minds

#2. Want more? Ready, Set, Go! A few brain teasers to flex those cog­ni­tive muscles

#3. “[Breath­ing tech­niques] are allow­ing you to con­scious­ly take con­trol of your breath­ing so you can take con­trol of your ner­vous sys­tem so you can take con­trol of your anx­i­ety” — James Nestor, author of Breath: The New Sci­ence of a Lost Art. New book shares sci­ence and tech­niques to breathe bet­ter and pro­mote calm­ness not anxiety

#4. Voice does matter…especially in areas of poten­tial dis­agree­ment. To call, or to text, that is the (men­tal well-being) question

#5. Fas­ci­nat­ing research + inno­va­tion event brought by the Euro­pean Insti­tute of Inno­va­tion & Tech­nol­o­gy (EIT) and mul­ti­ple part­ners. Save the Date: Pro­mot­ing Brain Health for Life, Decem­ber 15–16th, online.

#6. “This isn’t a bat­tle between AI and doc­tors, it’s about how to opti­mize doc­tors’ abil­i­ty to deliv­er bet­ter care” — P. Murali Doraiswamy, direc­tor of the Neu­rocog­ni­tive Dis­or­ders Pro­gram at Duke Uni­ver­si­ty. Next: Ana­lyz­ing typ­ing speed, speech and sleep pat­terns to iden­ti­fy cog­ni­tive decline, demen­tia, Parkinson’s, and more

#7. Google’s X team shares 3 valu­able lessons learned from their ambi­tious and (for the time being) unsuc­cess­ful moon­shot: Alphabet’s X shares Amber EEG sys­tem to expand the quest for men­tal health biomarkers

#8. “An exer­cise pre­scrip­tion is an impor­tant treat­ment option and a great adjunct to med­ica­tions. The key is pre­scrib­ing phys­i­cal activ­i­ty in a way that the patient will com­ply and remain engaged with.” Debate: How should doc­tors pre­scribe exer­cise to ensure com­pli­ance and engagement?

#9. As the study authors note, “The expan­sion of women into the labor force in the mid-20th cen­tu­ry may have pro­vid­ed a new avenue of cog­ni­tive reserve for women via enhanced social stim­u­la­tion and cog­ni­tive engage­ment.” Study: Work in adult­hood seen to sig­nif­i­cant­ly delay mem­o­ry decline after age 60, sup­port­ing the Cog­ni­tive Reserve theory

#10. “Through­out many sub­red­dits, we found sig­nif­i­cant increas­es in the use of tokens relat­ed to iso­la­tion (eg, “lone­ly,” “can’t see any­one,” “quar­an­tine”), eco­nom­ic stress (eg, “rent,” “debt,” “pay the bills”), and home (“fridge,” “pet,” “lease”), and a decrease in the lex­i­con relat­ed to motion (eg, “walk,” “vis­it,” “trav­el”).” Hope­ful­ly the promis­ing vac­cine news helps turn the tide; until then we need to pro­mote men­tal health & resilience hard. Using Red­dit as a pop­u­la­tion-lev­el “men­tal health track­er” dur­ing the COVID pandemic

#11. “BCI devices can be non-inva­sive devices that users wear, or they can be inva­sive devices, which are sur­gi­cal­ly implant­ed,” says Veljko Dublje­vi … “The inva­sive devices are more effi­cient, since they can read sig­nals direct­ly from the brain. How­ev­er, they also raise more eth­i­cal con­cerns. For exam­ple, inva­sive BCI tech­nolo­gies car­ry more asso­ci­at­ed risks such as surgery, infec­tion, and glial scar­ring — and inva­sive BCI devices would be more dif­fi­cult to replace as tech­nol­o­gy improves.” Stud­ies iden­ti­fy key eth­i­cal con­cerns raised by inva­sive and non-inva­sive neurotechnologies

#12. “(the app) uses the Watch’s sen­sors to track the heart rate and move­ment of users as they sleep. After estab­lish­ing a base­line pro­file for the patient with­in one or two nights’ sleep, the machine learn­ing algo­rithm spots heart rate or move­ment abnor­mal­i­ties pre­sum­ably caused by a night­mare. The appli­ca­tion then vibrates the smart­watch just enough to inter­rupt the wearer’s dream­ing, but not enough to wake them up or dis­rupt their cir­ca­di­an sleep cycle.” FDA grants clear­ance for Night­Ware app designed to reduce PTSD-relat­ed nightmares

 

Wish­ing you a safe and healthy December,

Alvaro Fer­nan­dez and the Sharp­Brains Team

 

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Filed Under: Brain Teasers, Brain/ Mental Health, Education & Lifelong Learning, Peak Performance, Technology & Innovation Tagged With: AI, anxiety, BCI, biomarker, Brain Teasers, Breathing, cognitive engagement, cognitive-reserve, disorders, doctors, EIT, European Institute of Innovation & Technology, exercise, FDA, Google, mental health, Moonshot, neurocognitive, neuroscience, prescription, Reddit, resilience, sleep, smartwatch, Thanksgiving, voice

Click Therapeutics and Boehringer Ingelheim partner to develop and market a digital therapeutic to treat schizophrenia

September 21, 2020 by SharpBrains

Boehringer Ingel­heim, Click Ther­a­peu­tics ink $500M+ dig­i­tal ther­a­peu­tics devel­op­ment, com­mer­cial­iza­tion deal (Mobi­Health­News):

Inter­na­tion­al phar­ma Boehringer Ingel­heim and pre­scrip­tion dig­i­tal ther­a­peu­tics com­pa­ny Click Ther­a­peu­tics have inked a $500 mil­lion-plus deal to joint­ly devel­op and com­mer­cial­ize a dig­i­tal treat­ment for patients with schiz­o­phre­nia. [Read more…] about Click Ther­a­peu­tics and Boehringer Ingel­heim part­ner to devel­op and mar­ket a dig­i­tal ther­a­peu­tic to treat schizophrenia

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: Boehringer Ingelheim, Click Therapeutics, CT-155, digital therapeutic, digital treatment, disorders, neuropsychiatric, neuropsychiatric disorders, pharma, prescription-based, schizophrenia

Digital mental health taking off in Europe

January 31, 2020 by SharpBrains

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These 10 Euro­pean tech star­tups want to help you improve your men­tal fit­ness (Sil­i­con Canals):

“Accord­ing to a report by WHO Euro (World Health Organ­i­sa­tion Europe), in many west­ern coun­tries, men­tal health dis­or­ders are the major cause of dis­abil­i­ty, account­ing for 30% to 40% of chron­ic sick leaves, and cost­ing near­ly 3% of GDP. In addi­tion to this, [Read more…] about Dig­i­tal men­tal health tak­ing off in Europe

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: Ahum, anxiety, artificial intelligence, depression, disability, disorders, drug use disorders, Flow Neuroscience, Healios, Humanoo, Medigold Health, mental health, mental health disorders, mental healthcare, Mental Snapp, mental-fitness, Meru Health, Moodpath, Psious, TalkLife, WHO Euro, World Health Organisation

Study finds psychiatric diagnoses to be ‘scientifically meaningless’

August 15, 2019 by SharpBrains

__________

Psy­chi­atric diag­no­sis ‘sci­en­tif­i­cal­ly mean­ing­less’ (Sci­ence Daily):

“A new study, pub­lished in Psy­chi­a­try Research, has con­clud­ed that psy­chi­atric diag­noses are sci­en­tif­i­cal­ly worth­less as tools to iden­ti­fy dis­crete men­tal health disorders.

The study, led by researchers from the Uni­ver­si­ty of Liv­er­pool, involved a detailed analy­sis of five key chap­ters of the lat­est edi­tion of the wide­ly used Diag­nos­tic and Sta­tis­ti­cal Man­u­al (DSM), on ‘schiz­o­phre­nia’, ‘bipo­lar dis­or­der’, ‘depres­sive dis­or­ders’, ‘anx­i­ety dis­or­ders’ and ‘trau­ma-relat­ed dis­or­ders’ [Read more…] about Study finds psy­chi­atric diag­noses to be ‘sci­en­tif­i­cal­ly meaningless’

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Filed Under: Brain/ Mental Health Tagged With: anxiety-disorders, bipolar-disorder, depressive disorders, diagnostic labelling, digital biomarkers, disorders, DSM, DSM-5, mental health, mental health disorders, psychiatric diagnosis, psychiatry research, schizophrenia, trauma-related disorders

Epigenetics research opens potential door to prevent neurodevelopmental disorders

August 20, 2018 by SharpBrains

Sai Ma, for­mer Vir­ginia Tech bio­med­ical engi­neer­ing Ph.D. stu­dent, and Chang Lu, the Fred W. Bull pro­fes­sor of Chem­i­cal Engi­neer­ing at Vir­ginia Tech. Cred­it: Vir­ginia Tech

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Epi­ge­net­ic Changes Guide Devel­op­ment of Dif­fer­ent Brain Regions (Dana Foundation):

“It’s one of the great­est stand­ing mys­ter­ies in neu­ro­science: Giv­en that each cell in the human body con­tains the same DNA, how, exact­ly, does the brain devel­op into dis­tinct func­tion­al regions, sup­port­ed by dif­fer­ent cell types? And how might that devel­op­men­tal pro­gram go awry, result­ing in neu­rode­vel­op­men­tal dis­or­ders like schiz­o­phre­nia or autism? The answers may be the epigenome [Read more…] about Epi­ge­net­ics research opens poten­tial door to pre­vent neu­rode­vel­op­men­tal disorders

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning, Technology & Innovation Tagged With: bioengineering, brain, cerebellum, clinical, disorders, DNA, epigenome, Neurodevelopmental, neurodevelopmental disorders, neurological, neuropsychiatric, neuroscience, Neurotechnology, prefrontal-cortex, SurfaceChIP

Study: Psychedelics can promote neural plasticity in the prefrontal cortex and expand pathways for mental health

August 17, 2018 by SharpBrains

– Cred­it: Cell Reports 2018 23, 3170–3182DOI: (10.1016/j.celrep.2018.05.022). Copy­right © 2018 The Authors

Psy­che­delics in Neu­rol­o­gy: Poten­tial for Improv­ing Neu­ro­plas­tic­i­ty (Neu­rol­o­gy­Times):

“Back in the 1950s, research was prov­ing that psy­che­del­ic agents could be effec­tive in the treat­ment of var­i­ous neu­ropsy­chi­atric dis­or­ders. Unfor­tu­nate­ly, just as sci­ence was explor­ing their ben­e­fi­cial effects, the coun­ter­cul­ture was explor­ing and embrac­ing their effects. Slow­ly but sure­ly, psy­che­delics were asso­ci­at­ed with rebel­lious youth and the tumul­tuous anti-war move­ment. As a result, the gov­ern­ment shut down most of the research.

The 1990s saw renewed inter­est in psy­che­del­ic com­pounds as a means to address neu­ropsy­chi­atric dis­or­ders. Research explored the ben­e­fits of MDMA and ket­a­mine to treat mood dis­or­ders and post­trau­mat­ic stress dis­or­der. Now, a new study sheds even more light on the promise these agents might pro­vide. [Read more…] about Study: Psy­che­delics can pro­mote neur­al plas­tic­i­ty in the pre­frontal cor­tex and expand path­ways for men­tal health

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: Aldous Huxley, Brain-Plasticity, depression, disorders, DMT, ketamine, LSD, MDMA, Michael Pollan, neural plasticity, neuroplasticity, neuropsychiatric, neuropsychiatric disorders, noribogaine, posttraumatic stress disorder, prefrontal-cortex, psychedelic, PTSD, spinogenesis, synaptogenesis, therapeutic

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