Mayo Clinic scientists have developed a computational model that predicts brain age using a large collection of neuroimaging data obtained using FDG-PET (fluorodeoxyglucose positron emission tomography) and structural MRI (magnetic resonance imaging). The deep learning-based model tests the relationship between brain age gaps in various forms of dementia, including mild cognitive impairment (MCI), Alzheimer’s disease (AD), frontotemporal dementia (FTD), and Lewy body dementia (LBD), as well as in normal brains.
What surprised you the most from the Judges’ questions and feedback during the Brainnovations Pitch Contest last month?
Even with only a brief presentation the judges immediately got the potential impact of our technology to measure and monitor brain health and began to think about other applications for us – several we had not thought about. That was fun.
In a nutshell, what is the core idea behind NeuraMetrix?
Typing Cadence is among the strongest habit we have. If the brain is attacked by a disease, the habit will begin to break – very slowly and in very small increments. Our way of measuring is so sensitive that we can pick up changes at the level of 1/100th of second – many orders of magnitude better than today’s tools.
When and how did the idea come to you?
Coming from data security, our first idea was to use typing cadence for authentication, and then were alerted to the brain health application by an outsider. [Read more…] about Jan Samzelius, CEO of Brainnovations Winner NeuraMetrix, encourages pioneers to focus on “simple, elegant solutions to big problems”
Time for SharpBrains’ August e‑newsletter, this time starting with a conversation whose time has come…
Year 2030, your college-age daughter, who has normal hearing, has been pounding on you to get the latest hearing aid that allows one to cancel out noise on demand, amplify selected ambient conversations at will, and can easily connect to the music store. Should you buy one for her? Maybe you should buy one not only for her, but also for you as you enter your 60s? Keep reading The Neurotech Revolution Could Lead To ‘Frankenstein’ Brains. Here’s How We Avoid It
- Executive Functions in Health and Disease
- Why we need “low-cost monitoring technologies to track cognitive processes at an individual level”, “people-centered wellness solutions that integrate brain health factors” and “interventions for healthy fetus/ baby development”
- Would you–or should you–undergo medical treatments to improve your body and mind and your chances of employment?
- Large study highlights the cognitive enhancement value of both higher education and lifelong learning
- Studies reinforce the critical importance of ADHD treatment monitoring
- AARP survey finds most common barrier for adults to add more mentally-stimulating activities: Knowing where to start
- Opioid inhibitor naltrexone (often used to treat addictions) can reduce feelings of social connection
- 16 Finalists announced @ MIT Solve’s Brain Health Challenge
- Suzhou Institute of Biomedical Engineering and Technology (SIBET) to host “brain-imaging factory”
- $3 million available for innovative solutions aimed at older adults via The Centre for Aging + Brain Health Innovation (CABHI)
- The National Science Foundation (NSF) funds Neurotechnology Hubs
- Brainy Innovation Tips from Edward Kliphuis, Investment Director with Merck Ventures
Upcoming events (and discount codes):
- September 6–7th, Washington, DC: BrainFutures and The Future of Brain Health and Enhancement (“sharpbrains” = $100 off)
- October 19–22nd, Los Angeles: Brain Longevity Therapy Training by the Alzheimer’s Research & Prevention Foundation (“sharpbrains” = $75 off). Also available as Livestream (“sharpbrainsLS” = $50 off)
- December 5–7th, online: Preliminary Agenda announced @ 2017 SharpBrains Virtual Summit: Brain Enhancement in the Digital Age (“sharp2017” = 10% off)
Have a great September!
The SharpBrains Team
Question: Charlie, please share 1–2 major brain health needs you observe right now whose solution demands a creative and significant tech-enabled innovation.
Answer: I’d encourage people to remember that Brain Health is just part of overall Whole Person Health. Brain health solutions may reduce some disease symptoms but not help achieve actual wellness. We need people-centered wellness solutions that integrate brain health factors.
What advice would you give an entrepreneur launching an innovation to address that?
Think hard about the way to grow and through what distribution channel you want to bring your solution. No distribution, no innovation.
– Charlie Hartwell is the Operating Partner at the Bridge Builders Collaborative, helping fund and support the visions of social entrepreneurs building bridges in the mind training space. Charlie is a Harvard Business School graduate who has led, founded, run and worked in organizations in 16 different industries. He will serve as a Judge in the first Brainnovations Pitch Contest hosted by the 2017 SharpBrains Virtual Summit: Brain Enhancement in the Digital Age (December 5–7th, 2017).
Neuroscience used to be the monopoly of a few elite universities located in a handful of countries. Neuropsychology used to be a quaint niche discipline relatively unconnected to the larger world of neuroscience and content in its methods with paper-and-pencil tests. [Read more…] about Executive Functions in Health and Disease: New book to help integrate Cognitive Neuroscience and Neuropsychology
“Understanding the human brain in health and disease represents a grand scientific challenge for the 21st century and beyond. How does a collection of 90 billion neurons interconnected by 150 trillion synapses give rise to the extraordinary capabilities of human behavior and the amazing diversity of talents among the billions of people populating our earth?” Keep reading The Human Connectome Project: Progress and Prospects over at the Dana Foundation website.
To learn more: