cognitive remediation

To treat depression, we will likely combine neuroplasticity-based brain training games with antidepressants

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BrainTrainingCom­put­er Games Bet­ter Than Med­ica­tion in Treat­ing Elder­ly Depres­sion (Live Science):

“Com­put­er games could help in treat­ing old­er peo­ple with depres­sion who haven’t been helped by anti­de­pres­sant drugs or oth­er treat­ments for the disorder…In a study of 11 old­er patients, researchers found play­ing cer­tain com­put­er games was just as effec­tive at reduc­ing symp­toms of depres­sion as [Read more…] about To treat depres­sion, we will like­ly com­bine neu­ro­plas­tic­i­ty-based brain train­ing games with antidepressants

May Update: Brain Training in Mental Health Toolkits for Prevention and Rehabilitation

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The use of a vari­ety of brain train­ing inter­ven­tions is grow­ing in the area of men­tal health. Emerg­ing evi­dence sug­gests that in the near future tar­get­ed brain train­ing may even be used to pre­vent sub­stance abuse. For exam­ple, train­ing work­ing mem­o­ry may reduce sub­stance abusers’ dis­count­ing of long-term rewards and pun­ish­ments — such dis­count­ing is one of the rea­sons why peo­ple sus­cep­ti­ble to addic­tions do not ben­e­fit from tra­di­tion­al informational/ edu­ca­tion­al approach­es to drug prevention.

Let’s explore some expand­ing appli­ca­tions of brain train­ing, and much more, in this lat­est edi­tion of the month­ly Sharp­Brains eNewslet­ter.

Brain Training and Mental Health

ADHD: Brain Train­ing, Neu­ro­feed­back, Diet, and More: What can be done to fight ADHD and improve the lives of peo­ple suf­fer­ing from it?

Neu­ro­plas­tic­i­ty in the Brain of Chil­dren with Neu­ro­log­i­cal Dis­or­ders: Brain train­ing may be an option for chil­dren suf­fer­ing from Tourette Syn­drom to help reduce the symptoms.

Brain Train­ing and Schiz­o­phre­nia: Social cog­ni­tive train­ing pro­grams can boost schiz­o­phren­ics’ skills social skills.

Rethink­ing the Clas­si­fi­ca­tion of Men­tal Ill­ness: How can we rethink the clas­si­fi­ca­tion of psy­chopathol­ogy (via the new DSM‑5) to reflect our cur­rent under­stand­ing of the brain as a dynam­ic system?

Upcom­ing events: Cog­ni­tive Reme­di­a­tion in Psy­chi­a­try (June 10th, NYC), Enter­tain­ment Soft­ware and Cog­ni­tive Neu­rother­a­peu­tics Soci­ety (Sep­tem­ber 19–20, San Francisco).

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Lifestyle for Brain Health

More Friends, Big­ger Brain: The num­ber of friends you have could be pre­dicted by the size of our amygdala!

Music and Demen­tia: Play­ing music pro­tects the brain lat­er on. Music may also be used to teach new facts to peo­ple suf­fer­ing from dementia.

Exer­cise and Over­weight Chil­dren: Aer­o­bic exer­cise can boost over­weight chil­dren exec­u­tive functions.

The Brain Grows With Prac­tice…: We know that when the brain mas­ters a new skill, tar­get­ed brain areas/ cir­cuits get enlarged. We now know that those areas and cir­cuits even­tu­ally shrink back to nor­mal, but per­for­mance gain can be maintained!

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Food for Thought

What is Brain Fit­ness? What are Emerg­ing Oppor­tu­ni­ties to Retool Brain Health? Here are the answers by sev­en 2011 Sharp­Brains Sum­mit Speakers.

Nav­i­gate through the 30 most pop­u­lar arti­cles of last year in SharpBrains.com to learn more about the brain and how to maintain/ enhance brain func­tion­ing across the lifes­pan..

Brain Teaser

Can you lis­ten to these laughs and dis­tin­guish whether it is a human or a com­puter laugh­ing? Also, giv­en how good laugh­ing is…how about try­ing this to find out how much stressed you are? You may be surprised.

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We hope you enjoyed this newslet­ter. Please do feel free to share this with friends and col­leagues via Face­book, Twit­ter and LinkedIn.

Schizophrenia Research is Leading the Way in Cognitive Remediation

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As announced by the NIMH a few months ago, schiz­o­phre­nia can now be con­sid­ered as a brain dis­or­der. Research is focus­ing on the cog­ni­tive deficits as the main prob­lem of the dis­or­der, prob­a­bly pre­ced­ing and per­haps lead­ing to the symp­toms of hal­lu­ci­na­tions and delusions.

A recent arti­cle in the Psy­chi­atric Times reviews the dif­fer­ent cog­ni­tive reme­di­a­tion tech­niques used with peo­ple suf­fer­ing from schiz­o­phre­nia. This is of inter­est to any­body work­ing on men­tal health. Indeed, as Sophia Vino­gradov, Inter­im Vice Chair Psy­chi­a­try at UCSF will dis­cuss dur­ing the Sharp­Brains Sum­mit (next week!) schiz­o­phre­nia is lead­ing the way in under­stand­ing how to iden­ti­fy and address brain-based cog­ni­tive deficits asso­ci­at­ed with the disorder.

…most [Cog­ni­tive Reme­di­a­tion (CR) pro­grams] are now com­put­er­ized. Some  pro­grams use a mix of gen­er­al edu­ca­tion­al soft­ware, but many train par­tic­i­pants with spe­cial­ized com­put­er soft­ware designed to improve cognition.

Most CR pro­grams aim to improve the cog­ni­tive domains usu­al­ly asso­ci­at­ed with deficits in schizophrenia—for instance ver­bal and visu­al work­ing mem­o­ry, exec­u­tive func­tion, atten­tion, and pro­cess­ing speed.

CR has been demon­strat­ed to improve over­all (glob­al) cog­ni­tion as well as spe­cif­ic domains, includ­ing atten­tion, exec­u­tive func­tion, work­ing mem­o­ry, ver­bal learn­ing and mem­o­ry, pro­cess­ing speed, and affect recognition.

Using Brain Plasticity to help Children with Learning Disabilities

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Did you read The Brain That Changes Itself: Sto­ries of Per­son­al Tri­umph from the Fron­tiers of Brain Sci­ence, the great book on neu­ro­plas­tic­i­ty by Nor­man Doidge? If  so, you will have heard about the Arrow­smith School/ Pro­gram, which was also one of the Top Ten Final­ists in 2010 Brain Fit­ness Inno­va­tion Awards.  The fol­low­ing is an excerpt from Brain School: Sto­ries of chil­dren with learn­ing dis­abil­i­ties and atten­tion dis­or­ders who changed their lives by improv­ing their cog­ni­tive func­tion­ing (Novem­ber 2010; $22), a new book from Eaton Arrow­smith School’s (EAS) founder and direc­tor, Howard Eaton. It tells the sto­ry of how chil­dren with learn­ing dis­abil­i­ties (dyslex­ia, ADHD, etc.) can over­come edu­ca­tion­al obsta­cles by reor­ga­niz­ing their brains. An inspir­ing book about how cog­ni­tive pro­grams can result in both aca­d­e­m­ic and social suc­cess.  [Read more…] about Using Brain Plas­tic­i­ty to help Chil­dren with Learn­ing Disabilities

Technology as the missing link to enable a brain-based model of brain care: interview with Dr. John Docherty

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Dr. John Docher­ty is an Adjunct Pro­fes­sor of Psy­chi­a­try at the Weill Med­ical Col­lege, Cor­nell Uni­ver­si­ty, Direc­tor of Post Grad­u­ate Edu­ca­tion there, and Chief Med­ical Offi­cer of Brain Resource. Trained as a clin­i­cal research fel­low in neu­ropsy­chophar­ma­col­o­gy at NIMH, he lat­er returned as Chief of the Psy­choso­cial Treat­ments Research Branch, respon­si­ble for all fed­er­al­ly sup­port­ed psy­choso­cial treat­ment research in men­tal health nation­wide. He over­saw the land­mark Nation­al Col­lab­o­ra­tive Study of the Treat­ment of Depres­sion and served as a mem­ber and Chair­man for over 10 years on the NIMH and then NIDA Treat­ment Research IRGs. Dr. Docher­ty has wide expe­ri­ence in suc­cess­ful­ly imple­ment­ing inno­va­tion in both clin­i­cal oper­a­tions and man­aged health care. He found­ed North­east Psy­chi­atric Asso­ciates in 1985. As Nation­al Med­ical Direc­tor for Nation­al Med­ical Enter­pris­es, he over­saw med­ical con­trol and qual­i­ty improve­ment in 74 hos­pi­tals in 34 states. He was the Exec­u­tive Vice-Pres­i­dent and Chief Med­ical Offi­cer for Mer­it Behav­ioral Care, which then cov­ered 30 mil­lion peo­ple. In 1998, he found­ed Com­pre­hen­sive Neu­ro­Science (CNS). Its Care Man­age­ment Tech­nolo­gies are cur­rent­ly imple­ment­ed in 17 state Med­ic­aid plans. Dr Docher­ty has received numer­ous hon­ors and awards and has authored over 100 sci­en­tif­ic publications.

(Edi­tor’s note: this inter­view with Dr. John Docher­ty was orig­i­nal­ly pub­lished in Sharp­Brains’ mar­ket report Trans­form­ing Brain Health with Dig­i­tal Tools to Assess, Enhance and Treat Cog­ni­tion across the Lifes­pan, pub­lished in July 2010)

Alvaro Fer­nan­dez: Dr. Docher­ty, it is a plea­sure to be with you today to dis­cuss the main theme of Sharp­Brains’ 2010 mar­ket report – how the con­ver­gence of sci­en­tif­ic find­ings and tech­nol­o­gy plat­forms and tools is reshap­ing how as a soci­ety and as indi­vid­u­als we will take care of cog­ni­tion and men­tal well­ness along the life­course, giv­ing birth to the emerg­ing dig­i­tal brain health and fit­ness mar­ket. Can you first briefly dis­cuss your career tra­jec­to­ry and your cur­rent role at Brain Resource?

Dr. John Docher­ty: Sure. The main theme of my work since the 1960s has remained the same, “How do we put knowl­edge into effec­tive use to improve men­tal health?” Over the last cen­tu­ry, med­i­cine made tremen­dous progress in gen­er­at­ing sci­en­tif­ic and clin­i­cal knowl­edge. Basic research dis­cov­ery sci­ence and clin­i­cal treat­ment devel­op­ment sci­ence have made great progress. With­in Psy­chi­a­try there was stan­dard set­ting advance in the 1960’s through the NIMH-VA coop­er­a­tive stud­ies to the method­ol­o­gy of assess­ing the effi­ca­cy of psy­chophar­ma­co­log­i­cal drugs. This work estab­lished prin­ci­ples adopt­ed for the study of med­ica­tions in the oth­er areas of med­i­cine. The study of psy­chother­a­py, how­ev­er, lagged in devel­op­ment. In my role of Chief of the Psy­choso­cial Treat­ments Branch of the NIMH , I helped con­tribute to the advance of that work by sup­port­ing the efforts of an extra­or­di­nary group of indi­vid­u­als led by Irene Waskow who car­ried out the TDCRP. This study estab­lished the method­olo­gies that made pos­si­ble the effec­tive sci­en­tif­ic study of the effi­ca­cy of psy­chother­a­pies. The evi­dence base and of such treat­ments as CBT, DBT, Moti­va­tion­al Enhance­ment Treat­ment and oth­er evi­dence-based psy­chother­a­pies derives direct­ly from this study and its sem­i­nal influ­ence. This was a con­tri­bu­tion to the sci­ence of Clin­i­cal Treat­ment Devel­op­ment research.

I would say that my major inter­est, how­ev­er, has been in the next step, the sci­ence of knowl­edge trans­fer. There has been and remains a long and cost­ly (in terms par­tic­u­lar­ly of unnec­es­sary suf­fer­ing) lag between the devel­op­ment of new knowl­edge and its com­mon and effec­tive use in practice.

In order the help the field moved for­ward, I have worked for the last 20 years in the devel­op­ment and imple­men­ta­tion of meth­ods to effec­tive­ly trans­fer knowl­edge into prac­tice. [Read more…] about Tech­nol­o­gy as the miss­ing link to enable a brain-based mod­el of brain care: inter­view with Dr. John Docherty

Update: Expo Day; Top 15 Articles of 2009

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In this Jan­u­ary issue of our eNewslet­ter, we will first neuronsbrief you on the enlight­en­ing demos that will take place on Wednes­day, Jan­u­ary 20th, as part of the Sharp­Brains Sum­mit, and then present the 15 most stim­u­lat­ing Sharp­Brains arti­cles of 2009.

Expo Day

If you want to see and dis­cuss the lat­est pro­grams and tech­nolo­gies for brain fit­ness, pre­sent­ed by Sum­mit Spon­sors, Wednes­day Jan­u­ary 20th is your day. Each demo will last 30 min­utes, fol­lowed by 15 min­utes of Q&A.

9am. Baycrest/ Cog­nic­i­ti will intro­duce the new Memory@Work work­shop, designed to teach what mem­o­ry is, how lifestyle fac­tors such as dis­trac­tion and stress can affect mem­o­ry, and how to enhance mem­o­ry per­for­mance at work with the use of enabling strategies.

10am. Cog­niFit will demo Cog­niFit Per­son­al Coach and Cog­niFit Senior Dri­ver, two online pro­grams designed to assess and main cog­ni­tive func­tions for healthy liv­ing and safe dri­ving, respectively.

11am. Posit Sci­ence will demo InSight, a soft­ware-based cog­ni­tive train­ing pack­age designed to sharp­en brain’s visu­al sys­tem. This is the pro­gram being test­ed by All­state for safer driving.

Noon. Hap­py Neu­ron will intro­duce HAP­PYneu­ron PRO, a new plat­form for pro­fes­sion­als for the effec­tive deliv­ery and man­age­ment of cog­ni­tive reme­di­a­tion and reha­bil­i­ta­tion pro­grams in a patient cen­tric manner.

1pm. Sharp­Brains will help nav­i­gate this grow­ing field by dis­cussing The State of the Brain Fit­ness Soft­ware 2009 report and The Sharp­Brains Guide to Brain Fit­ness con­sumer guide, and sum­ma­riz­ing key Sum­mit take-aways.

Learn more and reg­is­ter HERE. Please remem­ber that reg­is­tra­tion clos­es on Jan­u­ary 17th.

We want to thank our most recent spon­sor, the Arrow­smith Pro­gram, a com­pre­hen­sive suite of cog­ni­tive pro­grams for stu­dents with learn­ing dis­abil­i­ties avail­able in pub­lic and pri­vate schools in Cana­da and the U.S. More infor­ma­tion here.

And now, let’s review the (in our view) 15 most stim­u­lat­ing arti­cles of 2009.

The Big Picture

100 is the new 65: Why do some peo­ple live, and well, to 100? Researchers are try­ing to find out, reports Meera Lee Sethi at Greater Good Magazine.

Learn­ing about Learn­ing: an Inter­view with Joshua Wait­zkin: Scott Bar­ry Kauf­man inter­views “child prodi­gy” Joshua Wait­zkin on The Art of Learning.

Debunk­ing 10 Brain Health Myths: Does your brain have a “Brain Age”? Is a Mag­ic Pill to pre­vent mem­o­ry prob­lems right around the corner?  Check out the facts to debunk 10 com­mon myths.

Why is work­ing mem­o­ry rel­e­vant to read­ing and math­e­mat­ics: A recent large UK study iden­ti­fied 1 in 10 stu­dents as hav­ing work­ing mem­o­ry dif­fi­cul­ties. Dr. Tra­cy Alloway elab­o­rates why this matters.

Change Your Envi­ron­ment, Change Your­self: Dr. Brett Steen­barg­er explains why new envi­ron­ments  “force us to exit our rou­tines and active­ly mas­ter unfa­mil­iar challenges.”

Tools

Retool­ing Use it or lose it: Alvaro Fer­nan­dez dis­cuss­es why rou­tine, doing things inside our com­fort zones, is the most com­mon ene­my of the nov­el­ty, vari­ety and chal­lenge our brains need.

Does cog­ni­tive train­ing work? (For Whom? For What?): Dr. Pas­cale Mich­e­lon, dis­sects a cou­ple of recent press releas­es and the under­ly­ing stud­ies to clar­i­fy­ing what they mean – and what they don’t mean.

New Study Sup­ports Neu­ro­feed­back Treat­ment for ADHD: Dr. David Rabin­er reports the promis­ing find­ings from the first well-designed con­trolled tri­al on the effect of neu­ro­feed­back treat­ment for ADHD.

Do Art Class­es Boost Test Scores? Is there a “Mozart Effect?”: Some researchers sug­gest so; oth­ers are not con­vinced. Karin Evans offers a  thought­ful review of the evi­dence and asks, “Now, is this the right question?”

Does cof­fee boost cog­ni­tive func­tions over time? Dr. Pas­cale Mich­e­lon reports good news (long-term effects seem more pos­i­tive than neg­a­tive, so cof­fee leads to no clear harm) and bad ones (no clear ben­e­fi­cial effects on gen­er­al brain functions).

Indus­try

Brain fit­ness heads towards its tip­ping point: How do you know when some­thing is mov­ing towards a Glad­wellian tip­ping point? When insur­ance com­pa­nies and pol­i­cy mak­ers pay atten­tion, Dr. Ger­ard Finnemore reports.

Visu­al Rep­re­sen­ta­tion of the State of the Mar­ket 2009: Paul Van Slem­brouck beau­ti­ful­ly presents the main find­ings of our 150-page mar­ket report, The State of the Brain Fit­ness Mar­ket 2009.

Michael Merzenich on brain fit­ness: neu­ro­sci­en­tist Michael Merzenich dis­cuss­es neu­ro­plas­tic­i­ty, tech­nol­o­gy, safe dri­ving, men­tal health, and the need for stan­dards, auto­mat­ed assess­ments and “personal brain trainers”.

Brain Teas­er

Stim­u­late your Con­cen­tra­tion Skills: when one real­ly wants to mem­o­rize a fact, it is cru­cial to pay atten­tion. Dr. Pas­cale Mich­e­lon chal­lenges you to count a few sim­ple letters.

Res­o­lu­tion

Final­ly, an arti­cle that may inspire some New Year Res­o­lu­tions. In Yes, You Can Build Willpow­er, Daniel Gole­man dis­cuss­es how the brain makes about 10,000 new cells every day, how they migrate to where they are need­ed, and how each cell can make around 10,000 con­nec­tions to oth­er brain cells. Impli­ca­tion? Med­i­tate, mind­ful­ly, and build pos­i­tive habits.

Wish­ing you a Hap­py and Pro­duc­tive 2010, and look­ing for­ward to meet­ing many of you (200 so far) at the inau­gur­al Sharp­Brains Sum­mit!