Cognitive-impairment

Pilot program by IU and Davos Alzheimer’s Collaborative to test AI-powered cognitive screening at scale

by Leave a Comment

How AI, Dig­i­tal Screen­ing Tools Can Help Flag Ear­ly Cog­ni­tive Decline (Health IT Analytics):

Ear­ly diag­no­sis of Alzheimer’s and oth­er demen­tias remains at the fore­front of efforts to min­i­mize the impact of these neu­rode­gen­er­a­tive dis­eases. But chal­lenges such as increased life expectan­cy and the risks of aging, along with com­plex­i­ties in diag­no­sis and treat­ment result­ing from mixed brain patholo­gies, make ear­ly detec­tion dif­fi­cult … A new pilot pro­gram at Indi­ana Uni­ver­si­ty School of Med­i­cine and Indi­ana Uni­ver­si­ty Health, in col­lab­o­ra­tion with the Davos Alzheimer’s Col­lab­o­ra­tive (DAC), seeks to tack­le these issues using dig­i­tal screen­ing tools. [Read more…] about Pilot pro­gram by IU and Davos Alzheimer’s Col­lab­o­ra­tive to test AI-pow­ered cog­ni­tive screen­ing at scale

Digital therapeutics pioneer Akili Interactive Labs goes public, raising $150M+; trades down 49% first day

by

Akili Inter­ac­tive is the lat­est com­pa­ny to go pub­lic via SPAC deal (Boston Busi­ness Journal):

Boston’s Akili Inter­ac­tive Labs Inc. is the lat­est Mass­a­chu­setts-based com­pa­ny to go pub­lic after com­plet­ing a reverse merg­er — in a year of mar­ket tur­moil that saw few local firms pass­ing the thresh­old between pri­vate and pub­lic status.

Shares of Akili start­ed trad­ing on Mon­day on the Nas­daq Cap­i­tal Mar­ket under the new tick­er sym­bol “AKLI” after the com­pa­ny com­plet­ed its pre­vi­ous­ly announced reverse merg­er with Social Cap­i­tal Suvret­ta Hold­ings Corp. I (Nas­daq: DNAA), a spe­cial pur­pose acqui­si­tion com­pa­ny, or SPAC. [Read more…] about Dig­i­tal ther­a­peu­tics pio­neer Akili Inter­ac­tive Labs goes pub­lic, rais­ing $150M+; trades down 49% first day

Deep learning model built on neuroimaging data identifies “Brain Age Gaps” as markers of Alzheimer’s disease (AD)

by

Brain Age Gap is a Com­pos­ite Bio­mark­er for Demen­tia Pathol­o­gy or Sever­i­ty (GEN):

Mayo Clin­ic sci­en­tists have devel­oped a com­pu­ta­tion­al mod­el that pre­dicts brain age using a large col­lec­tion of neu­roimag­ing data obtained using FDG-PET (flu­o­rodeoxyglu­cose positron emis­sion tomog­ra­phy) and struc­tur­al MRI (mag­net­ic res­o­nance imag­ing). The deep learn­ing-based mod­el tests the rela­tion­ship between brain age gaps in var­i­ous forms of demen­tia, includ­ing mild cog­ni­tive impair­ment (MCI), Alzheimer’s dis­ease (AD), fron­totem­po­ral demen­tia (FTD), and Lewy body demen­tia (LBD), as well as in nor­mal brains.

[Read more…] about Deep learn­ing mod­el built on neu­roimag­ing data iden­ti­fies “Brain Age Gaps” as mark­ers of Alzheimer’s dis­ease (AD)

New book provides practical guidance for women (and men) to rebalance our lifestyles and build Cognitive Reserve

by

On one of our “walk and talks” around the lush trails of Rock Creek Park in DC sur­round­ed by bik­ers, run­ners, cars and the occa­sion­al deer, Wendy and Lisa talked about aging. Wendy’s moth­er, who had her chil­dren in her ear­ly 20s, was still join­ing the family’s gru­el­ing sum­mer hikes with her chil­dren and nine grand­chil­dren well into her 60s. Wendy mused about how much old­er she would be when their kids could have their own kids. It dawned on her that her health was not just a here and now issue, but an invest­ment in that future. We agreed to help each oth­er cul­ti­vate the habits and make time to build strength as well as reserves, both phys­i­cal and men­tal, for the long-term. Their goal: to enjoy being active in their 40s and 50s while also lay­ing the ground­work to con­tin­ue being active into their 60s, 70s, and beyond. [Read more…] about New book pro­vides prac­ti­cal guid­ance for women (and men) to rebal­ance our lifestyles and build Cog­ni­tive Reserve

Geisinger and Eisai to test real-world validity of AI-powered Passive Digital Marker (PDM) in detecting early cognitive impairment and dementia

by

Research col­lab­o­ra­tion will test nov­el algorithm’s effec­tive­ness on Geisinger data (press release):

Geisinger and Eisai Inc. today announced a col­lab­o­ra­tive effort to study the poten­tial effec­tive­ness of an arti­fi­cial intel­li­gence (AI) tool in the detec­tion of cog­ni­tive impair­ment that could iden­ti­fy demen­tias, includ­ing Alzheimer’s dis­ease (AD). If effec­tive, the AI tool could poten­tial­ly be devel­oped to sup­port the ear­ly detec­tion and stag­ing of cog­ni­tive impair­ment and demen­tia, lead­ing to appro­pri­ate addi­tion­al test­ing for the clin­i­cal, bio­log­i­cal diag­no­sis and treat­ment of demen­tias such as AD. [Read more…] about Geisinger and Eisai to test real-world valid­i­ty of AI-pow­ered Pas­sive Dig­i­tal Mark­er (PDM) in detect­ing ear­ly cog­ni­tive impair­ment and dementia

Study: Education and lifestyle helped over a million older Americans avoid serious cognitive problems in 2017

by

Study: More U.S. seniors, espe­cial­ly women, retain­ing health brains (UPI):

The per­cent­age of old­er Amer­i­cans report­ing seri­ous prob­lems with mem­o­ry and think­ing has declined in recent years — and high­er edu­ca­tion lev­els may be part of the rea­son, a new study finds. [Read more…] about Study: Edu­ca­tion and lifestyle helped over a mil­lion old­er Amer­i­cans avoid seri­ous cog­ni­tive prob­lems in 2017