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clinical-diagnosis

Study: Artificial intelligence program identifies linguistic markers that predict, with 70% accuracy, who gets Alzheimer’s Disease years later

February 3, 2021 by SharpBrains

Fig. 3. Cook­ie-theft pic­ture descrip­tion task (CTT) exam­ples from the Fram­ing­ham Heart Study, includ­ing an unim­paired sam­ple (a), an impaired sam­ple (b), and an even more impaired sam­ple show­ing sig­nif­i­cant mis­spellings and min­i­mal gram­mat­ic com­plex­i­ty ©. Cred­it: Eyigoz et al (2020)

Alzheimer’s Pre­dic­tion May Be Found in Writ­ing Tests (The New York Times):

… the researchers looked at a group of 80 men and women in their 80s — half had Alzheimer’s and the oth­ers did not. But, sev­en and a half years ear­li­er, all had been cog­ni­tive­ly nor­mal. [Read more…] about Study: Arti­fi­cial intel­li­gence pro­gram iden­ti­fies lin­guis­tic mark­ers that pre­dict, with 70% accu­ra­cy, who gets Alzheimer’s Dis­ease years later

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: Alzheimers-disease, artificial intelligence, biomarker, clinical-diagnosis, cognitive decline, Cognitive-tests, cognitively, dementia, Framingham Heart Study, impairment, linguistic analysis, MCI, neuropsychological, predict Alzheimer's disease

New online cognitive self-assessment by Cogniciti (Baycrest): a thermometer for the mind?

May 27, 2014 by SharpBrains

thermometersBay­crest mem­o­ry experts launch ‘ther­mome­ter’ for the mind (Press release):

“Accord­ing to the test’s cre­ators, the major­i­ty of peo­ple will score in the nor­mal, healthy range for their age – which will help reas­sure the “wor­ried well”. For the small per­cent­age (approx­i­mate­ly 2 — 3%) that scores below aver­age for [Read more…] about New online cog­ni­tive self-assess­ment by Cog­nic­i­ti (Bay­crest): a ther­mome­ter for the mind?

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: Baycrest, brain health test, Brain-health, chronic-stress, clinical-diagnosis, Cogniciti, cognitive problems, dementia. Anxiety, depression, diabetes, sleep apnea, thermometer, worried well

Alzheimer’s Early and Accurate Diagnosis: Normal Aging vs. Alzheimer’s Disease

April 29, 2009 by Dr. Murali Doraiswamy

(Edi­tor’s Note: I recent­ly came across an excel­lent book and resource, The Alzheimer’s Alzheimer's Disease Action PlanAction Plan: The Experts’ Guide to the Best Diag­no­sis and Treat­ment for Mem­o­ry Prob­lems, just released in paper­back. Dr. Murali Doraiswamy, one of the authors and lead­ing Alzheimer’s expert, kind­ly helped us cre­ate a 2‑part arti­cle series to share with Sharp­Brains read­ers advice on a very impor­tant ques­tion, “How can we help the pub­lic at large to dis­tin­guish Alzheimer’s Dis­ease from nor­mal aging — so that an inter­est in ear­ly iden­ti­fi­ca­tion does­n’t trans­late into unneed­ed wor­ries?” What fol­lows is an excerpt from the book, pages 3–8).

—

Jane, fifty-sev­en, man­aged a large sales force. She prid­ed her­self on being good at names, and intro­duc­tions were easy for her—until last spring when she referred to Bar­bara as Bet­ty at a meet­ing and had to cor­rect her­self. She start­ed notic­ing that her mem­o­ry wasn’t as depend­able as it once was—she had to real­ly try to remem­ber names and dates. Her moth­er had devel­oped Alzheimer’s in her late sev­en­ties, so Jane enter­tained a wide array of wor­ries: Is this just aging? Is it because of menopause? Is it ear­ly Alzheimer’s? Did her cowork­ers or fam­i­ly notice her slips? Should she ask them? Should she see a doc­tor, and if so, which doc­tor? Would she real­ly want to know if she was get­ting Alzheimer’s? Would she lose her job, health insur­ance, or friends if she did have Alzheimer’s?

As it turns out, Jane did not have Alzheimer’s. She con­sult­ed a doc­tor, who, in doc­s­peak, told her that the pas­sage of time (get­ting old­er) had tak­en a slight toll on her once-superquick mem­o­ry. She was slow­ing down a lit­tle, and if she relaxed, the name or date or oth­er bit of infor­ma­tion she need­ed would come to her soon enough. She was still good at her job and home life. She had sim­ply joined the ranks of the wor­ried well.

Nor­mal brain aging, begin­ning as ear­ly as the for­ties in some peo­ple, may include:

  • Tak­ing longer to learn or remem­ber information
  • Hav­ing dif­fi­cul­ty pay­ing atten­tion or con­cen­trat­ing in the midst of distractions
  • For­get­ting such basics as an anniver­sary or the names of friends
  • Need­ing more reminders or mem­o­ry cues, such as promi­nent appoint­ment cal­en­dars, reminder notes, a phone with a well­stocked speed dial

Although they may need some assis­tance, old­er peo­ple with­out a men­tal dis­or­der retain their abil­i­ty to do their errands, han­dle mon­ey, find their way to famil­iar areas, and behave appropriately.

How does this com­pare to a per­son with Alzheimer’s? When Alzheimer’s slows the brain’s machin­ery, peo­ple begin to lose their abil­i­ty to [Read more…] about Alzheimer’s Ear­ly and Accu­rate Diag­no­sis: Nor­mal Aging vs. Alzheimer’s Disease

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Filed Under: Brain/ Mental Health Tagged With: Alzheimers, Alzheimers-Action-Plan, Alzheimers-disease, Alzheimers-Disease-diagnosis, Alzheimers-symptoms, attention, brain--test, brain-aging, brain-tests, clinical-diagnosis, cognitive-function, concentrating, dementia, dementia-screening-interview, executive-function, Forgetting, impair-memory, judgment, medication-side-effects, memory-loss, memory-tests, mental-disorder, mental-function, Murali-Doraiswamy, normal-aging, reasoning, remember-names, stroke, sudden-onset, thinking

Shall we question the brand new book of human troubles

December 20, 2008 by Dr. Vaughan Bell

With three years still left until pub­li­ca­tion, the fights over the new ver­sion of the psy­chi­atric diag­nos­tic man­u­al, the DSM‑V, are hot­ting up and The New York Times has a bookcon­cise arti­cle that cov­ers most of the main point of contention.

- “What you have in the end,  Mr. Short­er said, “is this process of sort­ing the deck of symp­toms into syn­dromes, and the out­come all depends on how the cards fall.

- Psy­chi­a­trists involved in prepar­ing the new man­u­al con­tend that it is too ear­ly to say for sure which cards will be added and which dropped.

Although I doubt the DSM com­mit­tee are using that exact metaphor, it cer­tain­ly illus­trates the point that the process requires a cer­tain degree of value-judgement.

It’s inter­est­ing, how­ev­er, that the pub­lic debate is cur­rent­ly focused on whether cer­tain diag­noses should be includ­ed or not, rather than whether diag­no­sis itself is use­ful for psychiatry.

We’ve had psy­cho­met­rics for a good 100 years that allow us to mea­sure dimen­sions of human expe­ri­ence and per­for­mance with a much greater degree of accu­ra­cy than [Read more…] about Shall we ques­tion the brand new book of human troubles

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Filed Under: Brain/ Mental Health Tagged With: clinical-diagnosis, diabetes, diagnostic, diagnostic-manual, DSM, DSM-V, human-troubles, hypertension, insurance, obesity, psychiatric, psychiatric-diagnostic, Psychiatrists, psychometrics, symptoms, syndromes

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