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chemotherapy

Growing research shows how two of the major cancer treatments, radiation and chemotherapy, can lead to long-term cognitive impairment

June 5, 2020 by SharpBrains

Mind jum­ble: Under­stand­ing chemo brain (Stan­ford Medicine):

Sarah Liu was treat­ed for leukemia as a teenag­er. She attend­ed her high school grad­u­a­tion on a four-hour pass from Lucile Packard Children’s Hos­pi­tal Stan­ford and was bald under her white grad­u­a­tion cap, her arm ban­daged where she’d been receiv­ing chemother­a­py drugs.

Liu sur­vived can­cer and the ordeal of her treat­ment, and for many years she thrived. But today, at 53, she strug­gles to remem­ber the names of all the Stan­ford oncol­o­gists who helped her, though she reveres them for sav­ing her life. Many years lat­er, her child­hood can­cer treat­ments — chemother­a­py and radi­a­tion — have left her brain muddled…She’s among the legions of can­cer sur­vivors suf­fer­ing from chemo brain, a neu­ro­log­i­cal dis­or­der for­mal­ly known as chemother­a­py-relat­ed cog­ni­tive impairment…

[Read more…] about Grow­ing research shows how two of the major can­cer treat­ments, radi­a­tion and chemother­a­py, can lead to long-term cog­ni­tive impairment

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: astrocyte, chemo-brain, chemobrain, chemotherapy, chemotherapy-related cognitive impairment, cognitive difficulties, Cognitive-impairment, microglia, myelin, oligodendrocyte, OPC

Finally, growing awareness of chemotherapy-induced cognitive deficits

May 29, 2014 by SharpBrains

fog brainBrain activ­i­ty changes seen after chemo (Reuters):

“For some women with breast can­cer, changes in brain activ­i­ty while mul­ti­task­ing could explain “chemo brain” – reduced men­tal func­tion­ing that many expe­ri­ence after chemother­a­py, Bel­gian researchers say. “Cog­ni­tive com­plaints of peo­ple increase with chemother­a­py and [Read more…] about Final­ly, grow­ing aware­ness of chemother­a­py-induced cog­ni­tive deficits

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Filed Under: Brain/ Mental Health, Technology & Innovation Tagged With: brain-activity, breast cancer, chemo-brain, chemotherapy, cognitive complaints, cognitive risks, mental-performance, multitasking

Measuring and treating Chemo Brain

October 3, 2012 by SharpBrains

‘Chemo Brain’ After Breast Can­cer Backed by Study (US News):

“Breast can­cer patients treat­ed with chemother­a­py are at risk for mild men­tal deficits known col­lec­tive­ly as “chemo brain,” a new study finds. Researchers at the Mof­fitt Can­cer Cen­ter in Tam­pa, Fla., reviewed exist­ing research on brain func­tion (“cog­ni­tive” func­tion­ing) in [Read more…] about Mea­sur­ing and treat­ing Chemo Brain

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Filed Under: Brain/ Mental Health Tagged With: brain-function, breast cancer, chemo-brain, chemotherapy, cognitive, cognitive-function, Cognitive-Training, neuropsychological, neuropsychological-tests, speed-of-processing

Update: Time to become mental capitalists and invest in our brains?

November 30, 2011 by Alvaro Fernandez

Time for the Novem­ber edi­tion of the month­ly Sharp­Brains eNewslet­ter, fea­tur­ing a wealth of resources and insights on how to invest in our brains, includ­ing top­ics such as brain health, med­i­ta­tion, neu­ropsy­chol­o­gy, brain train­ing games, chemo brain, dyslex­ia, neu­ro­plas­tic­i­ty, cog­ni­tive bias­es, stress, and more. Not to for­get a cou­ple of fun teasers. Enjoy!

Brain Fit­ness Q&A Sessions:

  • Tran­script: Alvaro Fer­nan­dez on Men­tal Cap­i­tal­ism and Non-inva­sive Cog­ni­tive Enhancement
  • Tran­script: Dr. Gary Small on Enhanc­ing Mem­o­ry and the Brain
  • Tran­script: Dr. Paul Nuss­baum on Med­i­ta­tion and Neuropsychology

The Big Picture:

  • Steve Jobs: Com­put­ers are the Bicy­cles of the Mind
  • Brain Fit­ness: Def­i­n­i­tion, Pri­or­i­ties, and Links to Neu­rolead­er­ship, by Alvaro Fernandez
  • Is the Uni­ver­si­ty Cen­tered on The Learn­er or the Pro­fes­sor?, by Miguel Angel Escotet
  • Grand Rounds: Best of Health and Med­ical Blog­ging, by Alvaro Fernandez

New Research:

  • Can Brain Train­ing Games and Biofeed­back Help Pre­vent Depres­sion, by Dr. Pas­cale Michelon
  • ‘Chemo Brain’: MRI Shows Brain Changes After Chemotherapy
  • Dyslex­ia not relat­ed to intel­li­gence. Impli­ca­tions for dis­crep­an­cy model?
  • Vet­er­ans learn to use yoga and med­i­ta­tion exer­cis­es to recon­nect with their emotions
  • Applied Neu­ro­plas­tic­i­ty: Rewiring the Brain to Ease Pain

New Books:

  • What makes your brain hap­py and why you should do the oppo­site, by David DiS­al­vo (We’ll have a Live Q&A on Decem­ber 9th)
  • How cog­ni­tive illu­sions blind us to reason
  • The Series on Stress & the Brain, by Dr. Jerome Schultz, con­tin­ues with: The Lit­tle Brain Down Under, The Stress Response Explained, The Human Brain Likes to Be in Bal­ance, To Fight, Flee or Freeze –That is the Question

Brain Teasers:

  • Math Teas­er: Unfin­ished The­sis, by Maria Lando
  • Math Teas­er: How to Choose a Mans Shirt, by Maria Lando
  • How many Share This Arti­cle links, right below, do you know how to use? Try a cou­ple of them and share via Face­book and Twitter!

Thank you for your inter­est and atten­tion and have a great December.

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Filed Under: Brain Teasers, Brain/ Mental Health, Education & Lifelong Learning, SharpBrains Monthly eNewsletter Tagged With: biofeedback, Books, brain, brain-books, Brain-Training, brain-training-games, chemo-brain, chemotherapy, cognitive illusions, cognitive-enhancement, depression, dyslexia, intelligence, meditation, memory, mental capitalism, neuroleadership, neuroplasticity, Neuropsychology, pain, Steve Jobs, Stress, veterans, yoga

Research on ‘Chemo Brain’: MRI Shows Brain Changes After Chemotherapy

November 17, 2011 by SharpBrains

‘Chemo Brain’: MRI Shows Brain Changes After Chemother­a­py (Med­scape):

- “Breast can­cer sur­vivors who have been treat­ed with chemother­a­py show sig­nif­i­cant changes in brain activ­i­ty, mea­sured by func­tion­al mag­net­ic res­o­nance imag­ing (fMRI), accord­ing to a study pub­lished in the Novem­ber issue of the Archives of Neu­rol­o­gy.”

- “The find­ing val­i­dates patients’ claims of reduced cog­ni­tive func­tion after receiv­ing chemother­a­py, a phe­nom­e­non referred to as “chemo brain,” said lead author Shel­li R. Kesler, PhD, from Stan­ford Uni­ver­si­ty School of Med­i­cine in California.”

Link to study Pre­frontal Cor­tex and Exec­u­tive Func­tion Impair­ments in Pri­ma­ry Breast Can­cer (Archives of Neu­rol­o­gy): [Read more…] about Research on ‘Chemo Brain’: MRI Shows Brain Changes After Chemotherapy

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Filed Under: Brain/ Mental Health Tagged With: behavioral impairments, biomarker, brain changes, breast cancer, Breast cancer survivors, chemo, chemo-brain, chemotherapy, executive function impairment, executive-function, fMRI, MRI, neurological impairment, neurology, prefrontal-cortex

Chemo Brain and Brain Training

May 5, 2011 by Dr. Pascale Michelon

Chemo brain or chemo fog refers to the cog­ni­tive changes that can occur dur­ing and after chemother­a­py. These changes may trans­late into mem­o­ry laps­es, motor prob­lems, dif­fi­cul­ty find­ing words and prob­lems man­ag­ing mul­ti­ple tasks and learn­ing new things. Although the caus­es of the phe­nom­e­non are still under debate, it is nonethe­less a real prob­lem, affect­ing 20% to 30% of breast can­cer patients who under­go chemother­a­py. This New York Time arti­cle reports that chemo brain effects may be longer last­ing than orig­i­nal­ly thought.

“Chemo brain,” the fog­gy think­ing and for­get­ful­ness that can­cer patients often com­plain about after treat­ment, may last for five years or more for a siz­able per­cent­age of patients, new research shows.

The study, pub­lished in The Jour­nal of Clin­i­cal Oncol­o­gy, is a vin­di­ca­tion of sorts for many can­cer patients, whose com­plaints about think­ing and mem­o­ry prob­lems are often dis­missed by doc­tors who lay blame for the symp­toms on nor­mal aging or the fatigue of illness.

What is offered to these patients to recov­er their brain func­tions faster? [Read more…] about Chemo Brain and Brain Training

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning Tagged With: Brain-Training, cancer-survivors, chemo-brain, chemo-fog, chemotherapy

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