brain-teaser

BrainHealth Week starts today! Plus: dancing, personalized mental health, brain stimulation and more

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Wel­come to a new edi­tion of Sharp­Brains e‑newsletter, annouc­ing the kick-off of Brain­Health Week and fea­tur­ing some stim­u­lat­ing resources and teasers.

#1. Brain­Health Week (Feb­ru­ary 20–24th) starts today:

Explore many fun events includ­ing a dai­ly text chal­lenge, a talk with the always great Dr. Tom Insel, and more!

#2. With­out Brain Health, you do not have Health

Impor­tant arti­cle giv­en that “It typ­i­cal­ly takes twen­ty to forty years or more for sci­en­tif­ic dis­cov­er­ies to mean­ing­ful­ly ben­e­fit human life. We can­not wait that long.” — Wise words!

#3. Sin Salud Cere­bral, Ust­ed no tiene Salud –same arti­cle, in Span­ish, for extra men­tal stim­u­la­tion and for sharing 🙂

“En los últi­mos diez años, los neu­ro­ci­en­tifi­cos hemos des­cu­bier­to mucho acer­ca de cómo fun­ciona el cere­bro, cómo mejo­rar la salud y el fun­cionamien­to del cere­bro y la mente a lo largo de la vida, y cómo esto con­tribuye a nues­tra salud y bien­es­tar en gen­er­al. Únase a nosotros y asegúrese de que los mejores años de su cere­bro están aún por venir, recor­dan­do que: Sin salud cere­bral, ust­ed no tiene salud.”

#4. Ball­room danc­ing can reduce aging-relat­ed brain atro­phy in the hip­pocam­pus (and, more than tread­mill walking!)

“(Danc­ing) gen­er­at­ed sig­nif­i­cant­ly greater improve­ments than tread­mill walk­ing on one mea­sure of exec­u­tive func­tion and on pro­cess­ing speed, which is the time it takes to respond to or process infor­ma­tion. Com­pared with walk­ing, danc­ing was also asso­ci­at­ed with reduced brain atro­phy in the hip­pocam­pus – a brain region that is key to mem­o­ry func­tion­ing and is par­tic­u­lar­ly affect­ed by Alzheimer’s dis­ease … We think that social danc­ing may be more ben­e­fi­cial than walk­ing because it is phys­i­cal­ly, social­ly and cog­ni­tive­ly demand­ing – and there­fore strength­ens a wide net­work of brain regions.”

#5. Alto Neu­ro­science rais­es $60M (equi­ty + cred­it) to help fix the “tri­al and error” approach to psy­chi­atric medication

“To do so, Alto is pair­ing a trove of data on EEG activ­i­ty, genet­ics, behav­ioral task mea­sure­ments and oth­er fac­tors to see which of its drugs fits best with patients who have depres­sion, post-trau­mat­ic stress dis­or­der and oth­er men­tal health con­di­tions. The company’s arti­fi­cial intel­li­gence plat­form homes in on three buck­ets: cog­ni­tion, emo­tion and sleep.”

#6. Voice bio­mark­er plat­form Sonde Health rais­es $19.25M to spread access to men­tal health mon­i­tor­ing and beyond

“GN Group will inte­grate Sonde’s Men­tal Fit­ness vocal bio­mark­er into its hear­ing prod­ucts. The com­pa­ny is already work­ing with Sonde to devel­op an MCI vocal bio­mark­er. Qual­comm, which has already inte­grat­ed Sonde’s vocal bio­mark­ers into its mobile device chipsets, has extend­ed the rela­tion­ship to include its wear­able chipsets.”

#7. The Euro­pean Soci­ety for Brain Stim­u­la­tion oppos­es EU reclas­si­fi­ca­tion of TMS and tDCS, claim­ing a flawed safe­ty assessment

“To put this into per­spec­tive, the like­li­hood of a seizure from rTMS (0.003%) is low­er than that asso­ci­at­ed with the use of anti­de­pres­sants and antipsy­chotics (0.1–1, 5%) … More­over, when such seizures occur they do so most­ly out­side the clinician’s office, by con­trast with rTMS (Per­era et al., 2016). For low inten­si­ty tDCS, tACS, tRNS seizure risk is com­plete­ly absent … As an organ­i­sa­tion and rep­re­sen­ta­tives of NIBS clin­i­cians and pro­fes­sion­als from across Europe, we, the ESBS, there­fore dis­agree with this EU deci­sion and in par­tic­u­lar with the fac­tu­al­ly incor­rect jus­ti­fi­ca­tions of that deci­sion to reclas­si­fy TMS and TES as inva­sive technologies”

Final­ly, a cou­ple of brain teasers to help you test your men­tal rota­tion cog­ni­tive skills:

#8. Can you read a map?

#9. Brain teas­er to stim­u­late your men­tal imagery, spa­tial rota­tion … and appetite

Have a great Brain­Health Week!

Update: Playing videogames may be more cognitively beneficial than other forms of screentime like social media, watching videos/ TV

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Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing time­ly brain & men­tal health news and a fun brain teas­er to put your tem­po­ral lobes to good use 🙂

#1. Study finds that play­ing videogames may be more cog­ni­tive­ly ben­e­fi­cial for chil­dren than oth­er forms of screen­time (social media, watch­ing videos/ TV)

“Here, we esti­mat­ed the impact of dif­fer­ent types of screen time (watch­ing, social­iz­ing, or gam­ing) on children’s intel­li­gence while con­trol­ling for the con­found­ing effects of genet­ic dif­fer­ences in cog­ni­tion and socioe­co­nom­ic sta­tus … Broad­ly, our results are in line with research on the mal­leabil­i­ty of cog­ni­tive abil­i­ties from envi­ron­men­tal fac­tors, such as cog­ni­tive train­ing and the Fly­nn effect.”

Fas­ci­nat­ing! Hav­ing said that…

#2. Large neu­roimag­ing study finds social iso­la­tion to be an ear­ly indi­ca­tor of increased demen­tia risk

“Social inter­ac­tion is huge­ly impor­tant. One study found that the size of our social group is actu­al­ly asso­ci­at­ed with the vol­ume of the orbitofrontal cor­tex (involved in social cog­ni­tion and emo­tion). But how many friends do we need? … It is hard to argue with the fact that humans are social ani­mals and gain enjoy­ment from con­nect­ing with oth­ers, what­ev­er age we are. But, as we are increas­ing­ly uncov­er­ing, it also cru­cial for the health of our cognition.”

#3. UC study finds near-trans­fer of cog­ni­tive train­ing to be nec­es­sary (yet not suf­fi­cient) for far-trans­fer, broad­er benefits

“Some peo­ple do very well in train­ing, such as play­ing a video game, but they don’t show near trans­fer, per­haps because they are using high­ly spe­cif­ic strate­gies,” said first author Anja Pahor … “For these peo­ple, far trans­fer is unlike­ly. By bet­ter under­stand­ing why this type of mem­o­ry train­ing or ‘inter­ven­tion’ works for some peo­ple but not oth­ers, we can move for­ward with a new gen­er­a­tion of work­ing-mem­o­ry train­ing games or use approach­es that are more tai­lored to indi­vid­u­als’ needs”

#4. Please help us recruit 30,000 adults for a UC Cit­i­zen Sci­ence project on cog­ni­tive training

“In our ongo­ing large-scale study (note: the one right above) we aim to recruit 30,000 adults who are moti­vat­ed and will­ing to help us bet­ter under­stand the fac­tors that under­lie learn­ing out­comes using a vari­ety of train­ing par­a­digms and out­come mea­sures. Our endeav­or will ulti­mate­ly con­tribute to the per­son­al­iza­tion of cog­ni­tive train­ing so that, hope­ful­ly, any­one who would like to improve their cog­ni­tive func­tion­ing will be able to choose the approach that may fit them best.” — researchers Susanne Jaeg­gi, Anja Pahor, Aaron Seitz @ UC Irvine/ Riverside

#5. Trend: Esports teams har­ness cog­ni­tive tests to bet­ter match play­er to task and to iden­ti­fy train­ing opportunities

Esports are bor­row­ing a page from Pro Sports’ book … we would­n’t be sur­prised to see the inverse tak­ing place too in just a few years.

#6. Dos and Don’ts of Ther­a­py on the Go: Nav­i­gat­ing the use of apps for men­tal health care

“For those with­out severe men­tal ill­ness, app-based ther­a­py may be help­ful in match­ing clients with a pro­fes­sion­al famil­iar with a range of prob­lems and stres­sors. This makes apps attrac­tive to those with anx­i­ety and mild to mod­er­ate depres­sion. They also appeal to peo­ple who wouldn’t ordi­nar­i­ly seek out office-based ther­a­py, but who want help with life issues such as mar­i­tal prob­lems and work-relat­ed stress.”

#7. AI-enabled chat­bot Wysa receives FDA Break­through Device des­ig­na­tion for patients with chron­ic pain, depres­sion and anxiety

Let’s talk!

#8. And here’s the Brain Teas­er: Ready to stim­u­late those neu­rons in your tem­po­ral lobes?

 

Wish­ing you and yours a healthy and fun summer!

Welcome to the Ultimate Neuroscience Lab: Your Smartphone

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Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing this time six sci­en­tif­ic reports and indus­try resources plus a fun illusion.

#1. Top 10 Men­tal Health Inno­va­tions to Watch: Spe­cial SciAm/ WEF report

Hop­ing you enjoy the great series over at Sci­en­tif­ic Amer­i­can and espe­cial­ly #7, titled Wel­come to the Ulti­mate Neu­ro­science Lab: Your Smart­phone, by Emory neu­roethi­cist Karen Rom­melfanger and our very own Álvaro Fer­nán­dez Ibáñez.

#2. Five thoughts to think about when think­ing about the speed of thought

The time it takes for all thoughts to occur is ulti­mate­ly shaped by the char­ac­ter­is­tics of the neu­rons and the net­works involved. Many things influ­ence the speed at which infor­ma­tion flows through the sys­tem, but three key fac­tors are: dis­tance, myeli­na­tion, complexity,

#3. Study: Self-guid­ed sleep app Sleepio, com­bined with stan­dard care for depres­sion and anx­i­ety, deliv­ers bet­ter out­comes than stan­dard care alone

“This eval­u­a­tion revealed sig­nif­i­cant val­ue in intro­duc­ing an evi­dence-based dig­i­tal sleep inter­ven­tion at scale with­in a clin­i­cal men­tal health ser­vice,” researchers from Big Health and Oxford Health NHS Foun­da­tion Trust conclude.

#4. On uncer­tain­ty, stress, emo­tion reg­u­la­tion, and carpe diem

“These find­ings from three stud­ies with diverse sam­ples and method­olo­gies under­score an upside to the specter of uncer­tain­ty: it can cause peo­ple to savor the pos­i­tives of the present.”

#5. Study finds ADHD is asso­ci­at­ed with dementia

“Specif­i­cal­ly, par­ents of an ADHD child have a 34% high­er risk of demen­tia and 55% high­er risk of Alzheimer’s, the results showed. Grand­par­ents have about an 11% increased risk of either condition.”

#6. Study: Few­er than 1% of geri­atric patients with cog­ni­tive com­plaints met Aduhelm research tri­al cri­te­ria. What can we expect about its real-world safety?

As the researchers point out, “It is thus clear how the result­ing gap between the research and “real world” fields is mas­sive.” We do have the impres­sion that the Aduhelm FDA saga is far from over.

#7. Quick brain teas­er: What do you see? And, can you unsee it?

Have a minute? Give it a try 🙂

 

Wish­ing you and yours a hap­py and healthy month of October,

The Sharp­Brains Team

On cognitive reframing and biases, stress, mental health tech, Aduhelm backlash, Britney Spears, and more

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Wel­come to a new edi­tion of Sharp­Brains’ e‑newsletter, fea­tur­ing this time nine sci­en­tif­ic reports and indus­try devel­op­ments to help pro­mote life­long brain and men­tal health.

#1. To low­er stress lev­els and improve prob­lem-solv­ing, prac­tice cog­ni­tive refram­ing instead of venting

“… vent­ing like­ly doesn’t soothe anger as much as aug­ment it. That’s because encour­ag­ing peo­ple to act out their anger makes them relive it in their bod­ies, strength­en­ing the neur­al path­ways for anger and mak­ing it eas­i­er to get angry the next time around. Stud­ies on vent­ing anger (with­out effec­tive feed­back), whether online or ver­bal­ly, have also found it to be gen­er­al­ly unhelp­ful … To get out of that, you can ask the per­son to step back and help you reframe your expe­ri­ence by ask­ing, “How should I think about this dif­fer­ent­ly?” or “What should I do in this situation?”

#2. Head­space and Gin­ger merge to expand and scale up dig­i­tal men­tal health

“The new com­pa­ny would find it push­ing well beyond its cur­rent mind­ful­ness focus to, “pro­vide the full spec­trum of proven, effec­tive vir­tu­al sup­port – from mind­ful­ness and med­i­ta­tion, to text-based behav­ioral health coach­ing, to video-based ther­a­py and psy­chi­a­try – for all types of patient populations.”

Ambi­tious move!

#3. How to read, under­stand and write great med­ical research

12 good tips for stu­dents and every­one else

#4. Vet­er­ans Affairs won’t cov­er Biogen’s new “Alzheimer’s drug” giv­en con­cerns over safe­ty and lack of evidence

Their inde­pen­dent review con­cludes that “giv­en the lack of evi­dence of a robust and mean­ing­ful clin­i­cal ben­e­fit and the known safe­ty sig­nal, we rec­om­mend against offer­ing this agent to patients with Alzheimer’s demen­tia (mild or oth­er­wise) or mild cog­ni­tive impairment.”

#5. Alzheimer’s & Demen­tia researchers chal­lenge FDA’s approval of Aduhelm giv­en lack of evi­dence for beta-amy­loid as a marker

A strong call to “learn how this reg­u­la­to­ry fail­ure occurred and to ensure that it doesn’t occur again”

#6. Debunk­ing four myths about deci­sion-mak­ing capac­i­ty to keep Brit­ney Spears and oth­ers safe

Address­ing the ongo­ing con­tro­ver­sy about con­ser­va­tor­ships, a USC Pro­fes­sor of Law, Psy­chol­o­gy, and Psy­chi­a­try shares a great arti­cle to debunk these all-too-com­mon myths

#7. Study exam­ines com­mon cog­ni­tive bias­es (have you tried this brain teas­er?) and ways to mit­i­gate them

If you have not encoun­tered the “Lin­da brain teas­er” before, please give it a try! If you have, you’ll enjoy the new paper titled Tver­sky and Kahneman’s Cog­ni­tive Illu­sions: Who Can Solve Them, and Why?

#8. Inte­grat­ing music, move­ment and stroke reha­bil­i­ta­tion, MedRhythms rais­es $25M to devel­op and com­mer­cial­ize dig­i­tal therapeutic

Fas­ci­nat­ing approach to gait training.

#9. Neu­rotech start-up Paradromics rais­es $20M to address brain-relat­ed dis­or­ders via next-gen brain-com­put­er interfaces

Neu­ralink vs. Paradromics vs. non-inva­sive plat­forms — quite a stim­u­lat­ing space to track

 

Wish­ing you and yours a hap­py and healthy back-to-school and month of September,

The Sharp­Brains Team

Study examines common cognitive biases (have you tried this brain teaser?) and ways to mitigate them

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Pic: Get­ty Images

A fas­ci­nat­ing new study, Tver­sky and Kahneman’s Cog­ni­tive Illu­sions: Who Can Solve Them, and Why?, probes into the cog­ni­tive “heuris­tics and bias­es” researched by Daniel Kah­ne­man and Amos Tver­sky since the late 1960s.

If you have nev­er encoun­tered the “Lin­da brain teas­er” before, please give it a try:

Lin­da is 31 years old, sin­gle, out­spo­ken, and very bright. She majored in phi­los­o­phy. As a stu­dent, she was deeply con­cerned with issues of dis­crim­i­na­tion and social jus­tice, and also par­tic­i­pat­ed in anti-nuclear demonstrations.

Which state­ment is more probable?

(a) Lin­da is a bank teller.

(b) Lin­da is a bank teller and is active in the fem­i­nist movement.

 

Quick! What’s your answer? [Read more…] about Study exam­ines com­mon cog­ni­tive bias­es (have you tried this brain teas­er?) and ways to mit­i­gate them