brain health

Without Brain Health, you do not have Health

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As you go through life, your brain under­goes extra­or­di­nary devel­op­ment. Your brain is the most adapt­able, mod­i­fi­able organ in your body, and it can change both pos­i­tive­ly and neg­a­tive­ly by how you use it each day. Just by read­ing a book such as this one, your brain has been changed.

How has your brain been altered through­out your life? How may it change in years and decades ahead? The good news is that much of the age-relat­ed decline is like­ly avoid­able and even reversible. The fact that you bought and have read this book to the very end tells me you are moti­vat­ed to do some­thing about your brain per­for­mance. Our cog­ni­tive brain health tends to decline over time because we let it, but you can be your own brain health fit­ness coach to max­i­mize brain func­tion. Grow­ing brain research shows that a major­i­ty of indi­vid­u­als can make their brain smarter every sin­gle day. [Read more…] about With­out Brain Health, you do not have Health

Ballroom dancing can reduce aging-related brain atrophy in the hippocampus (and, more than treadmill walking!)

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Social ball­room danc­ing can improve cog­ni­tive func­tions and reduce brain atro­phy in old­er adults who are at increased risk for Alzheimer’s dis­ease and oth­er forms of demen­tia. That’s the key find­ing of my team’s recent­ly pub­lished study in the Jour­nal of Aging and Phys­i­cal Activity.

In our study, we enrolled 25 adults over 65 years of age in either six months of twice-week­ly ball­room danc­ing class­es or six months of twice-week­ly tread­mill walk­ing class­es. None of them were engaged in for­mal danc­ing or oth­er exer­cise pro­grams. [Read more…] about Ball­room danc­ing can reduce aging-relat­ed brain atro­phy in the hip­pocam­pus (and, more than tread­mill walking!)

On cognitive-physical training, brain biomarkers, dementia, ketamine, brain teasers, riddles and more

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Wel­come to the last 2022 edi­tion of Sharp­Brains e‑newsletter, fea­tur­ing a few select­ed brain health news and fun teasers to chal­lenge your brain and help us all think out­side the box.

#1. “Every­one agrees that Google Glass failed when it came to mar­ket, but to me, it’s a sym­bol of hope … It inspired peo­ple to think beyond tra­di­tion­al ways of mov­ing about our envi­ron­ment. Instead of look­ing down at a device, we could look out at the world and have an over­lay of dig­i­tal infor­ma­tion. It was one of the first steps in physical–digital con­ver­gence that we are see­ing today through­out many indus­tries. And as some­one who has cre­at­ed many inven­tions that nev­er left the lab or were too ear­ly for the mar­ket, I love the fact that Glass came out at all!” — wise words by neu­rotech entre­pre­neur Dr. Cori Lath­an in her new (and excel­lent) book. See Tech­nol­o­gy as a bridge in time: Shap­ing the future of brain health via today’s innovations–including those that “fail”

#2. “Some peo­ple want to do cog­ni­tive train­ing while mov­ing rather than sit­ting down, and that real­ly spoke to me as a pos­si­bil­i­ty for real ben­e­fits giv­en anec­do­tal sto­ries about games like ‘Dance Dance Rev­o­lu­tion.’” — Joaquin A. Anguera, asso­ciate pro­fes­sor at UCSF and direc­tor of Neuroscape‘s Clin­i­cal Divi­sion. See Study: A com­bined cog­ni­tive-phys­i­cal train­ing approach may enhance both mind and body as we age

#3. “Giv­en that ketamine’s rapid action and unex­pect­ed dis­so­cia­tive effects make it a poten­tial­ly worth­while option for treat­ing men­tal health prob­lems, we are on a mis­sion to unpack this mys­tery, at the cross­roads between phar­ma­col­o­gy and neu­ro­science.” See Study iden­ti­fies cog­ni­tive ben­e­fits of ket­a­mine in patients with treat­ment-resis­tant depression

#4. “The grat­i­tude writ­ing group main­tained grat­i­tude lev­els and decreased stress and neg­a­tive affect at one-month post-inter­ven­tion” — that main­te­nance aspect is espe­cial­ly inter­est­ing. See Thanks­giv­ing works: Grat­i­tude jour­nal­ing seen to low­er stress and neg­a­tive cog­ni­tive processes

#5. Impres­sive new funding–especially giv­en mar­ket conditions–with a goal to iden­ti­fy “brain bio­mark­ers by ana­lyz­ing EEG activ­i­ty, behav­ioral task per­for­mance, wear­able data, genet­ics, and oth­er fac­tors to match each patient with the right Alto drug.” See Pre­ci­sion psy­chi­a­try pio­neer Alto Neu­ro­science rais­es $35M to advance dig­i­tal bio­mark­er-to-treat­ment platform

#6. Some bad news. See The FDA ends pre­cer­ti­fi­ca­tion (Pre-Cert) pilot pro­gram, say­ing new author­i­ty required to reg­u­late soft­ware as a med­ical device (SaMD)

#7. And some great news: “(Péter Hudomi­et, study’s lead author) said it’s also pos­si­ble that, giv­en numer­ous stud­ies being released on steps to take to avoid demen­tia, some of the decline may be attrib­uted to peo­ple heed­ing such advice.” See Study finds sharp decrease (near­ly one-third) in the preva­lence of demen­tia among those 65+ in the Unit­ed States

#8. Final­ly, here are a few brain teasers to stim­u­late those neu­rons in your tem­po­ral lobes and to help us all think out­side the box.

 

Have a healthy and won­der­ful 2023!

 

Technology as a bridge in time: Shaping the future of brain health via today’s innovations–including those that “fail”

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Remem­ber Google Glass? Google invest­ed mil­lions of dol­lars and came to mar­ket in 2014 with the first gen­er­a­tion of wear­able aug­ment­ed real­i­ty (AR) tech­nol­o­gy. You could wear their cool head­sets with or with­out glass­es and use them to read and send email all while going about oth­er tasks.

Even before it was avail­able to the pub­lic, Glass cre­at­ed a huge amount of buzz. In 2013, every­one want­ed to get in on beta testing.

Almost every keynote speak­er I saw that year would come out wear­ing a Google Glass headset—and then invari­ably admit the bat­tery had run out weeks ago and they were just wear­ing it to look cool. I have to admit, I did the same.

Maybe that’s because it made me nos­tal­gic for a prod­uct we had designed about ten years ear­li­er, in 2005. Our Visu­al­ly Inte­grat­ed Sen­sor Unit, or VISUnit, was an ear­ly ver­sion of an AR head­set. [Read more…] about Tech­nol­o­gy as a bridge in time: Shap­ing the future of brain health via today’s innovations–including those that “fail”

Taking your brain vitals: Stories from a techno-optimist inventing the future of human performance

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Dr. Cori Lath­an, author of Invent­ing the Future: Sto­ries from a Techno-Optimist

For as long as I can remem­ber, my father loved act­ing. Into his six­ties and ear­ly sev­en­ties, he was quite active in the the­ater. He played Tartuffe in Molière’s Tartuffe, Nick Bot­tom in Shakespeare’s A Mid­sum­mer Night’s Dream, and the Old Man in Steve Martin’s Picas­so at the Lapin Agile. When he won the role of Scrooge in a local pro­duc­tion of Dickens’s A Christ­mas Car­ol, I was so excit­ed for him that I bought tick­ets way before open­ing night. But he was hav­ing trou­ble remem­ber­ing his lines. Even­tu­al­ly, the direc­tor had to let him go.

To find out what was going on, my mom and dad went to his pri­ma­ry care physi­cian, who referred him to a neu­rol­o­gist. After wait­ing a month for that appoint­ment, the neu­rol­o­gist told Dad to see a neu­ropsy­chol­o­gist, who was booked anoth­er three months out. When that appoint­ment arrived, the neu­ropsy­chol­o­gist gave him a vari­ety of cog­ni­tive tests, includ­ing writ­ten, ver­bal, and com­put­er based. After anoth­er month, the neu­rol­o­gist called us back in and told my father, “You have mild cog­ni­tive impairment.”

“No shit, Sher­lock,” I thought. “That’s why we went to see his doc­tor six months ago.” The neu­rol­o­gist then dis­cussed my father’s oth­er health issues with us, which includ­ed car­dio­vas­cu­lar dis­ease, sleep apnea, type 2 dia­betes, and by that point, depres­sion. I then had an inspi­ra­tion. “Dad, when was the last time you used your CPAP machine?” He admit­ted sheep­ish­ly, “I don’t use it. I don’t like it.” [Read more…] about Tak­ing your brain vitals: Sto­ries from a tech­no-opti­mist invent­ing the future of human performance

Study: Building muscle mass helps delay cognitive decline beyond the value of exercise itself

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A new rea­son to build mus­cle: brain health (The Globe and Mail):

… a recent study from researchers at McGill Uni­ver­si­ty, pub­lished in the jour­nal JAMA Net­work Open, offers a new rea­son for con­tin­u­ing to work on build­ing mus­cle: It’s good for your brain, not just your biceps. Greater mus­cle mass, the results sug­gest, helps ward off cog­ni­tive decline in old­er adults beyond what you’d expect based on their exer­cise lev­els alone. [Read more…] about Study: Build­ing mus­cle mass helps delay cog­ni­tive decline beyond the val­ue of exer­cise itself