Sharp Brains: Brain Fitness and Cognitive Health News

Neuroplasticity, Brain Fitness and Cognitive Health News

Icon

Build Your Cognitive Reserve: An Interview with Dr. Yaakov Stern

Yaakov SternDr. Yaakov Stern is the Divi­sion Leader of the Cog­ni­tive Neu­ro­science Divi­sion of the Sergievsky Cen­ter, and Pro­fes­sor of Clin­i­cal Neu­ropsy­chol­o­gy, at the Col­lege of Physi­cians and Sur­geons of Colum­bia Uni­ver­si­ty, New York. Alvaro Fer­nan­dez inter­views him here as part of our research for The Sharp­Brains Guide to Brain Fit­ness book.

Dr. Stern is one of the lead­ing pro­po­nents of the Cog­ni­tive reserve the­o­ry, which aims to explain why some indi­vid­u­als with full Alzheimer’s pathol­o­gy (accu­mu­la­tion of plaques and tan­gles in their brains) can keep nor­mal lives until they die, while oth­ers -with the same amount of plaques and tan­gles- dis­play the severe symp­toms we asso­ciate with Alzheimer’s Dis­ease. He has pub­lished dozens of peer-reviewed sci­en­tif­ic papers on the sub­ject.

The con­cept of a Cog­ni­tive Reserve has been around since 1989, when a post mortem analy­sis of 137 peo­ple with Alzheimer’s Dis­ease showed that some patients exhib­it­ed few­er clin­i­cal symp­toms than their actu­al pathol­o­gy sug­gest­ed. These patients also showed high­er brain weights and greater num­ber of neu­rons when com­pared to age-matched con­trols. The inves­ti­ga­tors hypoth­e­sized that the patients had a larg­er “reserve” of neu­rons and abil­i­ties that enable them to off­set the loss­es caused by Alzheimer’s. Since then, the con­cept of Cog­ni­tive Reserve has been defined as the abil­i­ty of an indi­vid­ual to tol­er­ate pro­gres­sive brain pathol­o­gy with­out demon­strat­ing clin­i­cal cog­ni­tive symp­toms. (You can check at the end of this inter­view a great clip on this).

———————————

Key take-aways

- Life­time expe­ri­ences, like edu­ca­tion, engag­ing occu­pa­tion, and leisure activ­i­ties, have been shown to have a major influ­ence on how we age, specif­i­cal­ly on whether we will devel­op Alzheimer’s symp­toms or not.

- This is so because stim­u­lat­ing activ­i­ties, ide­al­ly com­bin­ing phys­i­cal exer­cise, learn­ing and social inter­ac­tion, help us build a Cog­ni­tive Reserve to pro­tect us.

- The ear­li­er we start build­ing our Reserve, the bet­ter; but it is nev­er too late to start. And, the more activ­i­ties, the bet­ter: the effect is cumu­la­tive.

———————————

The Cog­ni­tive Reserve

Alvaro Fer­nan­dez (AF): Dear Dr. Stern, it is a plea­sure to have you here. Let me first ask you this: the impli­ca­tions of your research are pret­ty broad, pre­sent­ing major impli­ca­tions across sec­tors and age groups. What has been the most unex­pect­ed reac­tion so far?

YS: well…I was pret­ty sur­prised when Read the rest of this entry »

Brain Health for lawyers

The Com­plete Lawyer, a legal pub­li­ca­tion dis­trib­uted to bar mem­bers in sev­er­al states, just pub­lished an arti­cle on Ten Impor­tant Truths About Aging: How we age is at least par­tial­ly under our con­trol, By Elkhonon Gold­berg and Alvaro Fer­nan­dez.
We were hap­py to con­tribute to the ongo­ing debate about ethics and aging in the legal pro­fes­sion, build­ing on our pre­vi­ous post on the top­ic.
What are those “Ten Truths”? Well, here you are the out­line:

Keep Your Brain Nimble as You Age and Brain Fitness Events

Some good links today:

1) Keep Your Brain Nim­ble as You Age
MSNBC — May 13, 2007
“If using your com­put­er as a men­tal gym sounds good to you, SharpBrains.com’s Fer­nan­dez sug­gests ask­ing a few ques­tions first to deter­mine a product’s…”

2) Great blog by Stan­ford Busi­ness School’s Jack­son library, includ­ing an announce­ment of an upcom­ing lec­ture there by our very own Dr. Elkhonon Gold­berg and Alvaro Fer­nan­dez Pump­ing I.Q., not Iron

3) Some blog car­ni­vals (col­lec­tions of blog posts around spe­cif­ic top­ics)

All Slidedecks & Recordings Available — click image below

Search for anything brain-related in our article archives

About SharpBrains

As seen in The New York Times, The Wall Street Journal, BBC News, CNN, Reuters, and more, SharpBrains is an independent market research firm and think tank tracking health and performance applications of brain science.

Enter Your Email to receive Sharp­Brains free, monthly eNewslet­ter:

Join more than 50,000 Sub­scribers and stay informed and engaged.