Researchers found patients who used CCBT in addition to regular treatment led to “significantly greater improvement” on the Patient Health Questionnaire–9, used to screen for and measure depressive symptoms. Those results also held up over time.
“Results of this study show that treatment for depression in primary care can be enhanced by the addition of CCBT to TAU [treatment as usual],” the study’s authors wrote. “After 12 weeks of acute treatment, CCBT significantly outperformed TAU in reducing PHQ‑9 scores; these positive results were maintained over the 3- and 6‑month follow-up intervals. Remission rates were more than double for CCBT compared with TAU at all time points.” [Read more…] about Computer-assisted cognitive behavior therapy (CCBT) may outperform Treatment as Usual (TAU) in helping patients reduce depression, improve 6‑month remission rates
For people with post-traumatic stress disorder, recalling memories of physical or sexual assault, combat or disaster-related events can induce intense anxiety or panic attacks as well as debilitating flashbacks.
In the U.S., about 7% of people suffer from PTSD and lose an average of about four working days each month as a result. Trauma-specific psychotherapy, like cognitive processing or “talk” therapy, is the cornerstone of treatment for PTSD. But for approximately half of people, these traditional approaches are ineffective at fully addressing PTSD symptoms over the long term. Antidepressant drugs are frequently used if psychotherapy fails, or in combination with it, but the effects are usually modest. [Read more…] about Why MDMA-assisted psychotherapy may become an FDA-approved treatment for PTSD within 2 years
Every seven seconds, someone in the world is diagnosed with dementia. A typical case that I often see in my practice is as follows: A 76-year-old woman has a two-year history of progressive worsening of short-term memory and cognitive decline. She can’t recall the names of her grandchildren and is devastated by her deteriorating abilities.
However, this is not the first time in her life that she has had feelings of loss and despair. Over the past 30 years, she has intermittently struggled with depression and anxiety. Her family has many questions: Does she have dementia or Alzheimer’s? Could her depression have led to a dementia diagnosis? Is it only depression and not dementia? These are all good questions and the collective answer to them is “yes.” [Read more…] about Debate: Are depression and dementia two sides of the same coin? And, if they are, how to best approach treatment?
Otsuka Pharmaceutical is launching a virtual study to see if digital therapeutics can reduce depression symptoms.
It’s the next step in a partnership between the Tokyo-based drugmaker and Click Therapeutics, a digital health startup that is developing programs for smoking cessation, depression and insomnia. [Read more…] about Innovation in COVID times: Otsuka and Click Therapeutics announce fully virtual clinical trial, leveraging Verily’s Project Baseline
Brain-wave pattern can identify people likely to respond to antidepressant, study finds (Stanford Medicine press release):
“A new method of interpreting brain activity could potentially be used in clinics to help determine the best treatment options for depression, according to a study led by researchers at the Stanford School of Medicine.
Stanford researchers and their collaborators used electroencephalography, a tool for monitoring electrical activity in the brain, and an algorithm to identify a brain-wave signature in [Read more…] about Machine-learning study finds EEG brain signatures that predict response to antidepressant treatments
Why technology — not medication — is the future of treating older adults with depression (McKnight’s Long-term Care News):
“The go-to treatment for many cases of depression is medication.
Unfortunately, this treatment option can cause as many issues as the problem it is trying to solve. Antidepressants can put residents at greater risk of falls, negative health complications and other poor conditions. Some studies indicate that antidepressants may not be effective for most older Americans. [Read more…] about Could technology help cure depression among older adults? (Short answer: Yes)