Sharp Brains: Brain Fitness and Cognitive Health News

Neuroplasticity, Brain Fitness and Cognitive Health News

Icon

Sanofi Ventures leads $17M investment in Click Therapeutics, finalist @ 2017 Brainnovations Pitch Contest

___

Sanofi Backs Click Ther­a­peu­tics as Dig­i­tal Med­i­cines Gain Momen­tum (Xcon­o­my):

Drug mak­ers are mak­ing more bets on the nascent field of dig­i­tal med­i­cine. The lat­est exam­ple: Click Ther­a­peu­tics announced Mon­day that it grabbed a $17 mil­lion invest­ment led by Sanofi Ven­tures, the Cam­bridge, MA-based ven­ture cap­i­tal arm of the French phar­ma­ceu­ti­cal giant.

New York-based Click Ther­a­peu­tics devel­ops mobile apps intend­ed to be pre­scribed by doc­tors to treat med­ical con­di­tions, either on their own or in tan­dem with drugs or oth­er stan­dard treat­ments. The six-year-old com­pa­ny is work­ing on soft­ware that deliv­ers cog­ni­tive and “neu­robe­hav­ioral” exer­cis­es, aimed at treat­ing depres­sion, insom­nia, acute coro­nary syn­drome, and chron­ic pain…Click Ther­a­peu­tics already has a prod­uct on the mar­ket. “Click­o­tine” is an app designed to help peo­ple quit smok­ing, although the prod­uct doesn’t make any treat­ment claims and didn’t require FDA clear­ance to be mar­ket­ed to the pub­lic, accord­ing to a state­ment e‑mailed by a com­pa­ny spokesper­son.

Last year, Click pub­lished results of an ini­tial sin­gle-arm clin­i­cal tri­al of Click­o­tine in the JMIR mHealth and uHealth jour­nal. Dur­ing the eight-week study, the 416 par­tic­i­pants opened the app an aver­age of 100 times and con­tin­ued using it for an aver­age of 5.3 weeks. At the end of the study, 45.2 per­cent of the par­tic­i­pants report­ed they hadn’t smoked for at least sev­en days, and 26.2 per­cent of them said they hadn’t smoked for at least 30 days. The most com­mon side effects were fatigue and mood changes, accord­ing to the study.”

The Study:

Click­o­tine, A Per­son­al­ized Smart­phone App for Smok­ing Ces­sa­tion: Ini­tial Eval­u­a­tion (JMIR mHealth). From the abstract:

  • Back­ground: Tobac­co smok­ing is the lead­ing cause of pre­ventable death in the Unit­ed States, and the annu­al eco­nom­ic bur­den attrib­ut­able to smok­ing exceeds US $300 bil­lion. Obsta­cles to smok­ing ces­sa­tion include lim­it­ed access and adher­ence to effec­tive ces­sa­tion inter­ven­tions. Tech­nol­o­gy can help over­come these obsta­cles; many smart­phone apps have been devel­oped to aid smok­ing ces­sa­tion, but few that con­form to the US clin­i­cal prac­tice guide­line (USCPG) have been rig­or­ous­ly test­ed and report­ed in the lit­er­a­ture. Click­o­tine is a nov­el smart­phone app for smok­ing ces­sa­tion, designed to deliv­er the essen­tial fea­tures of the USCPG and engi­neered to engage smok­ers by per­son­al­iz­ing inter­ven­tion com­po­nents.
  • Objec­tive: Our objec­tive was to assess the engage­ment, effi­ca­cy, and safe­ty of Click­o­tine in an ini­tial, sin­gle-arm study. Out­comes mea­sured were indi­ca­tors of engage­ment with the smart­phone app (num­ber of app opens, num­ber of inter­ac­tions with the Click­o­tine pro­gram, and weeks active with Click­o­tine), ces­sa­tion out­comes of 7- and 30-day self-report­ed absti­nence from smok­ing, and neg­a­tive health events.
  • Con­clu­sions: In this ini­tial sin­gle-arm tri­al, Click­o­tine users appeared to demon­strate encour­ag­ing indi­ca­tors of engage­ment in terms of the num­ber of app opens, num­ber of pro­gram inter­ac­tions, and con­tin­ued engage­ment over time. Click­o­tine users report­ed encour­ag­ing quit rates while report­ing few adverse events. Future research is war­rant­ed to assess Clickotine’s effi­ca­cy in a ran­dom­ized con­trolled tri­al.

The News in Context:

Leave a Reply...

Loading Facebook Comments ...

Leave a Reply

Categories: Cognitive Neuroscience, Health & Wellness, Technology

Tags: , , , , , , , , , , ,

About SharpBrains

As seen in The New York Times, The Wall Street Journal, BBC News, CNN, Reuters,  SharpBrains is an independent market research firm tracking how brain science can improve our health and our lives.

Search in our archives

Follow us and Engage via…

twitter_logo_header
RSS Feed

Watch All Recordings Now (40+ Speakers, 12+ Hours)