RFA Now Open: CZI Neurodegeneration Challenge Network (Chan Zuckerberg Initiative release):
“The Chan Zuckerberg Initiative invites applications to join the CZI Neurodegeneration Challenge Network, an interdisciplinary collaborative initiative to increase understanding of the fundamental biology of neurodegenerative disorders. Applications are being accepted for two funding mechanisms:
- CZI Ben Barres Early Career Acceleration Awards: investigator awards for early career academic investigators, especially those who are new to the field of neurodegeneration
- CZI Collaborative Science Awards: awards for small group interdisciplinary collaborations that include a physician with active clinical engagement
…To encourage new ideas, we strongly encourage applications from researchers who are working in relevant fields outside of neurodegeneration and neuroscience (such as cell biology, immunology, metabolism, physiology, and computational biology). Previous work in neurodegeneration is not a prerequisite, as long as the proposal is able to make a strong case for potential relevance to neurodegeneration…
As part of the collective work of the Challenge Network, CZI will ask investigators to contribute to the development, validation and dissemination of robust, reliable, and scalable experimental and analytical tools for the broader neurodegeneration community. CZI will provide infrastructure support for such community tool development and dissemination efforts.
Examples of the types of tools and resources that the Challenge Network might develop and disseminate include but are not limited to:
- Scalable tools for cellular analysis, including genomic, proteomic, and imaging methods, optimized for human cells and relevance to neurodegeneration (for instance, targeted probes and label-free methods for cellular imaging of neurons and non-neuronal cells; robust affinity reagents for proteomics; genome editing and single cell genomic approaches)…
- Rigorous benchmark datasets for the field, for instance, well-validated longitudinal studies of disease progression that will inform more mechanistic approaches.
- Development and application of computational and machine learning approaches and tools to address neurodegeneration biology, which might include genomics, proteomics, metabolomics, systems biology, imaging, and/or integration of data across experimental models and scales.”
Learn more about the Request for Applications HERE.
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