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Monitoring neurological activity to detect epileptic seizures: Key Neurotech Patent #9

– Illus­tra­tive image from U.S. Patent No. 6,473,639


Today we are shar­ing a 2002 patent assigned to Neu­ropace, Inc. (As men­tioned, we are fea­tur­ing a foun­da­tion­al Per­va­sive Neu­rotech patent a day, from old­er to new­er by issue date)

U.S. Patent No. 6,473,639: Neu­ro­log­i­cal event detec­tion pro­ce­dure using processed dis­play chan­nel based algo­rithms and devices incor­po­rat­ing these pro­ce­dures.

  • Assignee(s): Neu­ropace, Inc.
  • Inventor(s): David R. Fis­chell, Jonathan Har­wood, Ben­jamin D. Pless
  • Tech­nol­o­gy Cat­e­go­ry: Neu­ro-mon­i­tor­ing
  • Issue Date: Octo­ber 29, 2002

SharpBrains’ Take:

The ‘639 patent dis­clos­es tech­niques for detect­ing neu­ro­log­i­cal activ­i­ty, name­ly the occur­rence of an epilep­tic seizure based on algo­rith­mic pro­cess­ing of sig­nals mea­sur­ing brain activ­i­ty. More specif­i­cal­ly, the sys­tem dis­cerns neu­ro­log­i­cal activ­i­ty by con­sid­er­ing brain sig­nal activ­i­ty based on the loca­tion of placed elec­trodes from which brain sig­nals orig­i­nat­ed, para­me­ters used in pro­cess­ing the sig­nal and a para­me­ters for detect­ing the even­t’s occur­rence that are unique to the patient. Despite some implantable embod­i­ment and claims that might appear to have a high word count, the scope of many claims (e.g., inde­pen­dent claims 1 and 36) have broad cov­er­age over non-inva­sive and cus­tomiz­able elec­trode-based detec­tion of neu­ro­log­i­cal activ­i­ty. The broad claim scope, cou­pled with the appli­ca­tion’s near­ly 200 for­ward cita­tions, make the ‘639 patent a key non-inva­sive neu­rotech­nol­o­gy patent.


This inven­tion relates gen­er­al­ly to infor­ma­tion pro­cess­ing tech­niques used in the treat­ment of epilep­sy and to devices for using these tech­niques.

Illus­tra­tive Claim 1. A device for detec­tion of neu­ro­log­i­cal event activ­i­ty in a patien­t’s brain com­pris­ing:

  • at least one brain elec­trode con­fig­ured to mon­i­tor brain elec­tri­cal sig­nals and pro­duce an out­put, each said brain elec­trode being posi­tion­able to a posi­tion rel­a­tive to a patien­t’s brain,
  • at least one processed dis­play chan­nel proces­sor con­fig­ured to pro­duce at least one processed dis­play chan­nel, said at least one processed dis­play chan­nel being a sig­nal pro­duced by sig­nal pro­cess­ing by said at least one processed dis­play chan­nel proces­sor, of a dig­i­tal sig­nal relat­ed to said out­put from said at least one brain elec­trode, the sig­nal pro­cess­ing hav­ing one or more para­me­ters;
  • a neu­ro­log­i­cal event detec­tor con­fig­ured to process the at least one processed dis­play chan­nel with at least one detec­tor algo­rithm to detect neu­ro­log­i­cal event activ­i­ty based upon
    • i.) the brain elec­tri­cal sig­nals received by the at least one brain elec­trode,
    • ii.) the posi­tion of each brain elec­trode,
    • iii.) the para­me­ters of the sig­nal pro­cess­ing used to cre­ate the at least one processed dis­play chan­nel,
    • iv.) and at least one detec­tor algo­rithms hav­ing at least one detec­tor para­me­ter cus­tomize­able for each patient.

To learn more about mar­ket data, trends and lead­ing com­pa­nies in the dig­i­tal brain health space –dig­i­tal plat­forms for brain/ cog­ni­tive assess­ment, mon­i­tor­ing and enhance­ment– check out this mar­ket report. To learn more about our analy­sis of 10,000+ patent fil­ings, check out this IP & inno­va­tion neu­rotech report.

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As seen in The New York Times, The Wall Street Journal, BBC News, CNN, Reuters,  SharpBrains is an independent market research firm tracking how brain science can improve our health and our lives.

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