Sharp Brains: Brain Fitness and Cognitive Health News

Neuroplasticity, Brain Fitness and Cognitive Health News


Study: Cognitive deficits continue long term in cancer survivors in domains important for social and executive functioning

elderly_senior_memory_loss_confusionCog­ni­tive Deficits Con­tin­ue Long Term in Can­cer Sur­vivors (Med­scape):

Although can­cer patients fre­quent­ly expe­ri­ence short-term cog­ni­tive deficits, lit­tle is known about how long these deficits last or whether they wors­en over time. Now, data from a large nation­al sam­ple sug­gest that cog­ni­tive deficits may per­sist long term.

When com­pared with matched indi­vid­u­als who were with­out can­cer, long-term can­cer sur­vivors per­formed worse on a test of pro­cess­ing speed, atten­tion, and learn­ing and work­ing mem­o­ry involv­ing exec­u­tive func­tions domains. Can­cer sur­vivors also more fre­quent­ly prob­lems with mem­o­ry and con­fu­sion, even after adjust­ing for con­founders, such as age and edu­ca­tion lev­el.

These effects appeared to be greater in long-term vs short-term can­cer sur­vivors, but age seemed to be a fac­tor. Can­cer sur­vivors aged 60 to 75 years had worse per­for­mance on the cog­ni­tion test as com­pared with those old­er than 75 years…

Although it is too soon to under­stand how this infor­ma­tion will affect cur­rent ther­a­peu­tic approach­es to old­er patients, Dr Markham said: “Clear­ly, we should be mind­ful of the impact of our treat­ments on cog­ni­tion in patients of all ages, includ­ing the advanced age pop­u­la­tion.”

Study: Cog­ni­tive func­tion in can­cer sur­vivors: Analy­sis of the 1999–2002 Nation­al Health and Nutri­tion Exam­i­na­tion Sur­vey (abstract pre­sent­ed at the 2016 Can­cer Sur­vivor­ship Sym­po­sium)

  • Back­ground: Can­cer and its treat­ment may affect cog­ni­tive func­tion in up to 35% of sur­vivors months after treat­ment. While short-term treat­ment-relat­ed cog­ni­tive changes are well rec­og­nized, only lim­it­ed research is avail­able in old­er, long-term sur­vivors of can­cer.
  • Con­clu­sions: This is the only study to exam­ine domain spe­cif­ic cog­ni­tive deficits in a large, nation­al­ly rep­re­sen­ta­tive, old­er pop­u­la­tion of long-term can­cer sur­vivors and the first to report deficits in pro­cess­ing speed, atten­tion, and learn­ing and work­ing mem­o­ry domains. These domains are thought to be impor­tant for social and exec­u­tive func­tion­ing and qual­i­ty of life. Char­ac­ter­iz­ing affect­ed domains and sub­pop­u­la­tions will help to devel­op and test effec­tive inter­ven­tions and may influ­ence treat­ment prac­tices in old­er can­cer patients.

To learn more:

Leave a Reply...

Loading Facebook Comments ...

Leave a Reply

Categories: Cognitive Neuroscience, Health & Wellness

Tags: , , , , , , , , , , , ,

All Slidedecks & Recordings Available — click image below

Search for anything brain-related in our article archives

About SharpBrains

As seen in The New York Times, The Wall Street Journal, BBC News, CNN, Reuters, and more, SharpBrains is an independent market research firm and think tank tracking health and performance applications of brain science.