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Brain Plasticity: How learning changes your brain

February 26, 2008 by Dr. Pascale Michelon

You may have heard that the brain is plastic.

As you well know. the brain is not made of plastic…Neuroplasticity, or brain plas­tic­i­ty, refers to the brain’s abil­i­ty to CHANGE through­out life.

The human brain has the amaz­ing abil­i­ty to reor­ga­nize itself by form­ing new con­nec­tions between brain cells (neu­rons).

In addi­tion to genet­ic fac­tors, the envi­ron­ment in which a per­son lives, as well as the actions of each per­son, play a sig­nif­i­cant role in plasticity.

Neu­ro­plas­tic­i­ty occurs in the brain…

1- At the begin­ning of life: when the imma­ture brain orga­nizes itself.

2- In case of brain injury: to com­pen­sate for lost func­tions or max­i­mize remain­ing functions.

3- Through adult­hood: when­ev­er some­thing new is learned and memorized

 

Plas­tic­i­ty, learn­ing and memory 

For a long time, it was believed that as we aged, the con­nec­tions in the brain became fixed, and then sim­ply fad­ed. Research has shown that in fact the brain nev­er stops chang­ing through learn­ing. Plas­tic­i­ty is the capac­i­ty of the brain to change with learning.

Changes asso­ci­at­ed with learn­ing occur most­ly at the lev­el of con­nec­tions between neu­rons: New con­nec­tions form and the inter­nal struc­ture of the exist­ing synaps­es change. Did you know that when you become an expert in a spe­cif­ic domain, the areas in your brain that deal with this type of skill will grow?

For instance, Lon­don taxi dri­vers have a larg­er hip­pocam­pus (in the pos­te­ri­or region) than Lon­don bus dri­vers. Why is that? It is because this region of the hip­pocam­pus is spe­cial­ized in acquir­ing and using com­plex spa­tial infor­ma­tion in order to nav­i­gate effi­cient­ly. Taxi dri­vers have to nav­i­gate around Lon­don where­as bus dri­vers fol­low a lim­it­ed set of routes.

Plas­tic­i­ty can also be observed in the brains of bilin­guals. It looks like learn­ing a sec­ond lan­guage is pos­si­ble through func­tion­al changes in the brain: the left infe­ri­or pari­etal cor­tex is larg­er in bilin­gual brains than in mono­lin­gual brains.

Plas­tic changes also occur in musi­cians brains com­pared to non-musi­cians. Gas­er and Schlaug com­pared pro­fes­sion­al musi­cians (who prac­tice at least 1hour per day) to ama­teur musi­cians and non-musi­cians. They found that gray mat­ter (cor­tex) vol­ume was high­est in pro­fes­sion­al musi­cians, inter­me­di­ate in ama­teur musi­cians, and low­est in non-musi­cians in sev­er­al brain areas involved in play­ing music: motor regions, ante­ri­or supe­ri­or pari­etal areas and infe­ri­or tem­po­ral areas.

Final­ly, Dra­gan­s­ki and col­leagues recent­ly showed that exten­sive learn­ing of abstract infor­ma­tion can also trig­ger some plas­tic changes in the brain. They imaged the brains of Ger­man med­ical stu­dents 3 months before their med­ical exam and right after the exam and com­pared them to brains of stu­dents who were not study­ing for exam at this time. Med­ical stu­dents’ brains showed learn­ing-induced changes in regions of the pari­etal cor­tex as well as in the pos­te­ri­or hip­pocam­pus. These regions of the brains are known to be involved in mem­o­ry retrieval and learning.

Plas­tic­i­ty and brain injury 

A sur­pris­ing con­se­quence of neu­ro­plas­tic­i­ty is the fact that the brain activ­i­ty asso­ci­at­ed with a giv­en func­tion can actu­al­ly move to a dif­fer­ent loca­tion as a con­se­quence of expe­ri­ence or brain damage.

In his book “The Brain That Changes Itself: Sto­ries of Per­son­al Tri­umph from the Fron­tiers of Brain Sci­ence,” Nor­man Doidge describes numer­ous exam­ples of func­tion­al shifts. In one of them, a sur­geon in his 50s suf­fers a stroke. His left arm is par­a­lyzed. Dur­ing his reha­bil­i­ta­tion, his good arm and hand are immo­bi­lized, and he is set to clean­ing tables. The task is at first impos­si­ble. Then slow­ly the bad arm remem­bers how too move. He learns to write again, to play ten­nis again: the func­tions of the brain areas killed in the stroke have trans­ferred them­selves to healthy regions!

The brain com­pen­sates for dam­age by reor­ga­niz­ing and form­ing new con­nec­tions between intact neu­rons. In order to recon­nect, the neu­rons need to be stim­u­lat­ed through activity.

Final­ly, let me address a cou­ple of ques­tions we often get…

Can new neu­rons grow in my brain?

Yes, and regard­less of how young or old you are. Here’s a good article.

Can you rec­om­mend a good book to learn more about neu­ro­plas­tic­i­ty and how to har­ness it for good?

Indeed. We pub­lished The Sharp­Brains Guide to Brain Fit­ness: How to Opti­mize Brain Health and Per­for­mance at Any Age pre­cise­ly to pro­vide a use­ful entry point into all this research and how to apply it. And we’re hap­py to report that it’s get­ting rave reviews!

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Filed Under: Brain/ Mental Health, Education & Lifelong Learning, Peak Performance Tagged With: Brain-Plasticity, change, Learning, london-bus-drivers, London-cab-drivers, memory, Norman-Doidge, The-Brain-That-Changes-Itself

Reader Interactions

Comments

  1. Mark Wiseman says

    February 26, 2008 at 6:06

    Real­ly inter­est­ing. Neu­ro­plas­tic­i­ty also plays a huge role in the devel­op­ment and main­te­nance of chron­ic pain.
    It appears that chron­ic pain is a learned neu­ro­log­i­cal response. It would be won­der­ful if some­one could devel­op and effec­tive way of unlearn­ing this response.

  2. Alvaro says

    February 26, 2008 at 7:05

    Hel­lo Mark, we are less famil­iar with pain research but I’d sus­pect what you say is right.

    In gen­er­al, the best way to “unlearn” a response is by learn­ing a new response that over­takes the pre­vi­ous one. 

    If you come across inter­est­ing research in that field, please let us know!

  3. Amol says

    February 26, 2008 at 8:42

    Just curi­ous,

    How does the “learn­ing” of how to use your sec­ond hand fit into this? i.e a right han­der becom­ing ambidexturous? 

    Are the same process­es involved in terms of rewiring between hemi­spheres of the brain? Is it pos­si­ble to devel­op hand­ed­ness by focus­ing on the skill or this some­thing more gene related?

    Thanks,

    Amol

  4. Pascale Michelon says

    February 27, 2008 at 7:58

    Hi Amol,
    I would think that learn­ing to use your non-dom­i­nant hand does involve plas­tic­i­ty. My guess is that the area in the motor cor­tex that cor­re­sponds to that hand will start devel­op­ing as a result of the increased move­ment in that hand.

  5. Bernard says

    February 27, 2008 at 8:01

    It is pre­cise­ly because the brain has neur­al plas­tic­i­ty that EEG neu­ro­feed­back works.

    Amol, the brain can retrain itself (strength­en­ing the new neu­ronal path­ways, when giv­en direc­tion via a biofeed­back sys­tem oper­at­ing on EEG measurements.

    It takes time for the new path­ways to become dominant/habitual, but once they do, the results of EEG neu­ro­feed­back are large­ly permanent.

    Sim­i­lar­ly, (but on the oppo­site end of the spec­trum), epilep­sy patients that do not get their seizure activ­i­ty under con­trol (only some­thing like 40% gain 100% con­trol through drug ther­a­py) are at risk of a process called kin­dling — where the brain learns/trains itself to seize. The wrong neu­ronal path­ways are being strength­ened in that case.

    I rec­om­mend hav­ing a look at Stephen Lar­son­’s book, The Heal­ing Pow­er of Neu­ro­feed­back: The Rev­o­lu­tion­ary LENS Tech­nique for Restor­ing Opti­mal Brain Func­tion. It ref­er­ences sev­er­al inter­est­ing stud­ies on the subject.

  6. Alvaro says

    February 27, 2008 at 8:50

    Bernard: neu­ro­plas­tic­i­ty explains why any kind of learn­ing can occur. It is a premise for all learn­ing. And a vari­ety of train­ing pro­grams, such as neu­ro­feed­back, can be help­ful in guid­ing neu­ro­plas­tic­i­ty in appro­pri­ate ways. 

    Now, the ques­tion is: what is the causal, direct, evi­dence that a giv­en train­ing inter­ven­tion is pro­duc­ing the right kind of learn­ing? Neu­ro­plas­tic­i­ty itself does not address that.

  7. Debbie says

    April 25, 2008 at 5:49

    I have a friend who is bare­ly 40 & had 2 strokes (clots). It has been 5 years. Her left side is par­a­lyzed. Then I saw a PBS show on neu­ro­plas­tic­i­ty. Is there some kind of PT or oth­er pro­gram I can do with her to help her brain re-learn? She is a good, kind, lov­ing per­son & does­n’t deserve to live like this.

  8. Alvaro says

    April 27, 2008 at 4:36

    Hel­lo Debbie,

    Your friend’s neu­ropsy­chol­o­gist would be the ide­al per­son to sug­gest what spe­cif­ic phys­i­cal and men­tal activ­i­ties ca help the reha­bil­i­ta­tion process. No two strokes affect the same areas.

    I hope she gets bet­ter. You may enjoy the superb book by the Woodruffs,
    In an Instant: A Fam­i­ly’s Jour­ney of Love and Heal­ing (Hard­cov­er)

  9. Padma says

    May 22, 2008 at 4:32

    Deb­bie
    Get the won­der­ful book of Dr.Jill Bolte Tay­lor who is a neu­roanatomist and had a stroke at 37, recov­ered com­plete­ly and advo­cates pas­sion­ate­ly treat­ment strate­gies forstork patients and their car­ers. It is called “My Stroke of insight” Her web­site http://www.drjilltaylor.com
    Goodluck

  10. Melody says

    June 29, 2008 at 4:59

    I am in a Lifes­pan Psy­chol­o­gy class right now, and we are study­ing brain plas­tic­i­ty. I would like to know if the brain can make new neur­al con­nec­tions to over­come trau­ma, can it also do the same, with train­ing, to over­come cer­tain men­tal ill­ness­es, such as depres­sion, schiz­o­phre­nia, or bipo­lar disorder?

  11. Alvaro says

    June 30, 2008 at 2:21

    Hel­lo Melody,

    The­o­ret­i­cal­ly, yes, of course (neu­ro­plas­tic­i­ty is the premise for learn­ing itself) but research is just emerg­ing in trau­ma-relat­ed areas.

    Some very promis­ing applications:
    — Cog­ni­tive ther­a­py for depres­sion and OCD
    — Com­put­er­ized cog­ni­tive train­ing for stroke/ TBI rehab

    There is research going on focused on schiz­o­phre­nia. We are not aware of spe­cif­ic tri­als on patients with bipo­lar disorder.

    In gen­er­al, I’d say: Stay Tuned. There will be a good num­ber of appli­ca­tions relat­ed to clin­i­cal con­di­tions. But the field is emerg­ing-no mag­ic cures today.

    Regards

  12. Anne McGinnis Breen says

    August 7, 2008 at 3:11

    Dear Good People,
    Just a note to say thanks for mar­ket­ing and wide­ly shar­ing the sci­en­tif­ic knowl­edge of neu­ro­ge­n­e­sis and adult neu­ro­plas­tic­i­ty with so many oth­ers. Learn­ing more about the amaz­ing brain and my own mind through cog­ni­tive ther­a­py and the free Dana Foun­da­tion pub­li­ca­tions has helped me to learn to use the com­put­er and oth­er edu­ca­tion­al tools to over­come some of the neu­ro­log­i­cal, emo­tion­al and social deficits of my own chron­ic med­ical con­di­tion, liv­ing with a recur­rent low-grade brain tumor in my left tem­po­ral lobe. Learn­ing new sci­en­tif­ic facts about our brain’s regen­er­a­tive pos­si­bil­i­ties gave me new hope for my own future many years ago. I hope some oth­er brain injured peo­ple will soon begin to share their own expe­ri­ences with some of these new cog­ni­tive retraining

  13. Anne McGinnis Breen says

    August 7, 2008 at 3:16

    (Ophs! I hit the sub­mit but­ton too soon by acci­dent!) I hope oth­ers will want to share their per­son­al results of the new brain train­ing tools and pro­grams here soon! GBYAY Anne McGin­nis Breen

  14. Pat says

    September 24, 2008 at 1:33

    Qt per­tain­ing to learn­ing a new ath­let­ic move­ment. I am a golf instruc­tor and the biggest chal­lenges to me are my old­er clients with years of poor habits. I under­stand the brain nev­er stops learn­ing, but what would be the best way to con­vince a per­son of 50 yrs old+ that has been play­ing golf their way for 20–30 yrs fun­da­men­tal­ly wrong and now wants to change? They may under­stand clear­ly what they need to do, but their body tells them dif­fer­ent­ly, in fact it tells them the new feel­ing is quite awk­ward — what is real­is­tic for their brain — neur­al path­ways to over­ride the old habit?

  15. Alvaro Fernandez says

    September 24, 2008 at 5:44

    Anne, thank you for shar­ing your sto­ry. In fact, hope is a need­ed ele­ment for improve­ment, and more and more jus­ti­fied with the grow­ing research behind neuroplasticity.

    Pat: great ques­tion. From a phys­i­cal “brain” point of view, the most impor­tant thing for you to know is that you can­not erase exist­ing pat­terns (pre­vent well-con­nect­ed neu­rons from fir­ing togeth­er, or erase those con­nec­tions), what you have to do is to build a new pat­tern (“neur­al path­way”) that with time and prac­tice will over­ride the pre­vi­ous one.

    Now, from a Ped­a­gogy point of view, may I also sug­gest that a) you don’t tell them (or even think!) that they are doing some­thing “fun­da­men­tal­ly wrong”. The point is that they can do it bet­ter. All of us can, includ­ing Tiger; b) you reas­sure them that “feel­ing quite awk­ward” is a nor­mal tran­si­tion phase when we are learn­ing a new skill. Sim­ply moti­vate them to con­tin­ue to rehearse and rehearse and come to enjoy the new pat­terns, and with prac­tice they will become the default habits.

    It is often said that “Cells that fire togeth­er, wire togeth­er”. Your ques­tion puts for­ward the Pros and Cons of such a system 🙂

  16. M. A. Greenstein says

    September 24, 2008 at 11:02

    Alvaro and Pat, a thought on the ped­a­gogy of move­ment behavior.

    Alvaro, I’m so pleased you not­ed the enjoy­ment of new pat­terns in the process of rehearsal.
    Help­ing peo­ple dis­cov­er new move­ment (brain) pat­terns and motifs invites both oppor­tu­ni­ties to enjoy an expand­ed sense of aes­thet­ics as well as a chance to return to the pri­ma­ry feel­ing of move­ment lib­er­at­ed from the shack­les of uncon­scious habit­u­al form. The uber tal­ent­ed bal­let mas­ter Barysh­nikov has been known to talk about going back to the basic barre to re-dis­cov­er the joy and sen­sa­tion of learn­ing the core val­ues of bal­let movement.

    To help stu­dents or clients reap the ath­let­ic rewards of neu­ro-plas­tic­i­ty, I found it help­ful to encour­age a cre­ative, “begin­ner’s mind” atti­tude in the rehearsal phase. And research on mind­ful move­ment does sug­gest a neu­ro­log­i­cal difference.

    Thoughts any­one?

    M. A. a.k.a. Dr. G.
    The George Green­stein Insti­tute for the Advance­ment of Somat­ic Arts and Science

  17. Tracy says

    October 3, 2008 at 5:55

    I am curi­ous to learn how to use brain plas­tic­i­ty to help me to con­tin­ue in my recov­ery from depres­sion. I love to learn new things and think that this con­cept can help explain why talk­ing to a ther­a­pist can lit­er­al­ly change the biol­o­gy of my brain. This has mys­ti­fied me but I think this con­cept helps to explain it.

  18. Tina says

    October 17, 2008 at 6:38

    Hello…I’m cur­rent­ly in a Lifes­pan Psy­chol­o­gy class and have some ques­tions regard­ing brain plas­tic­i­ty and the learn­ing of a new lan­guage. I’m try­ing to see if there is any cor­re­la­tion between learn­ing a new lan­guage and our bio­log­i­cal system. 

    If a tod­dler is adopt­ed by a new fam­i­ly that speaks a dif­fer­ent lan­guage from his/her bio­log­i­cal par­ent would that auto­mat­i­cal­ly trig­ger brain plac­tic­i­ty to occur? If so, what chem­i­cal changes hap­pen with­in the hip­pocam­pus? Are their oth­er areas of the brain that are involved in this process as well?

  19. james a. bellanca says

    October 17, 2008 at 12:00

    It is amaz­ing to read this newslet­ter and see all the sell­ers of “brain stuff” claim­ing to find some­thing new and won­der­ful-that the brain is plas­tic, not immutable. The most amaz­ing part is that these folks don’t have any inkling that they are not the pio­neers they claim to be. They might humbly go to the work of Israeli cogn­tive psy­chol­o­gist Reuven Feuer­stein who pos­tu­lat­ed the the­o­ry more of struc­tur­al cog­ni­tive mod­i­fi­a­bil­i­ty more than 50 years ago in his work with learn­ing impaired chil­dren. After they read Feuer­stein’s work, they will also see that he does­n’t make the out­landish claims that they do with their mir­a­cle prod­ucts. He knows that after all the work he and his col­leagues have done with severe­ly bain dam­aged chil­dren, brain trau­ma­tized adults and oth­ers, that what specif­i­cal­ly works to change the brain is still a very hyy­po­thet­i­cal ques­tion, not the quick fix answers that many, includ­ing peo­ple quot­ed in the newslet­ter, are sell­ing. Final­ly, he would sug­gest that just because a tool (includ­ing software)makes the brain change, there is very lit­tle hard evi­dence about how suc­cess­ful they are in pro­mot­ing learning.

  20. Alvaro Fernandez says

    October 17, 2008 at 1:01

    Tra­cy, cog­ni­tive ther­a­py is the brain train­ing modal­i­ty that has been shown to help patients with depres­sion, so I encour­age you to find a good prac­ti­tion­er. You may enjoy my inter­view with Judith Beck (see under Resources — Inter­views with Brain Sci­en­tists), which includes links to fas­ci­nat­ing studies.

    Tina: plas­tic­i­ty (the abil­i­ty to change respond­ing to expe­ri­ence) is a prop­er­ty of the brain. Our brain is chang­ing all the time. And, yes, sig­nif­i­cant envi­ron­men­tal changes (such as chang­ing coun­try and lan­guage) is going to accel­er­ate some changes due to the need for adap­ta­tion. A very inter­est­ing area of research is how being bilin­gual can reduce the prob­a­bil­i­ty of devel­op­ing Alzheimer’s symp­toms, pre­sum­ably via the Cog­ni­tive Reserve and the con­stant frontal lobe “work­out” need­ed to select words in the right language/ inhib­it words from the “wrong” language.

    James: you should prob­a­bly first dis­close that you are in the busi­ness of sell­ing ser­vices based on the the­o­ries that you are pro­mot­ing in your comment. 

    Sec­ond, and most impor­tant, I would encour­age you to share the pub­lished ref­er­ences of the effi­ca­cy of the pro­grams you advo­cate and seem to be sell­ing. 50 years of prac­tice means, I hope, that some high-qual­i­ty, ran­dom­ized, large-scale stud­ies have been per­formed and results pub­lished in the kind of jour­nals we can find in PubMed (from a health/ med­i­cine point of view) or in What Works Clear­ing­house (from an edu­ca­tion point of view).

    Talk­ing about the the­o­ries of one per­son ‑no mat­ter how admirable he/ she is‑, is not enough jus­ti­fi­ca­tion. Vygot­sky and Luria were cognitive/ neu­ropsych pio­neers since the ear­ly XX cen­tu­ry, yet I hope
    you would like to see some direct evi­dence of effi­ca­cy for any pro­gram that claims to be based on their admirable work.

    Final­ly, I am not sure where you find “quick fix­es” in this blog…exactly the oppo­site of what we are try­ing to do. As you point out well, tools are just that, tools, not mag­ic solutions.

  21. Gary D says

    October 24, 2008 at 10:00

    So, an old dog (like me) *can* learn new tricks! This is good news and encouraging.

    Ques­tion: why is it that learn­ing a sec­ond lan­guage is eas­i­er when you’re young as com­pared to when you’re old­er? And, from your per­spec­tive what can be done to make it easier..??

  22. Alvaro Fernandez says

    October 27, 2008 at 3:10

    Hel­lo Gary, I sug­gest you take a look at my inter­view with neu­ro­sci­en­tist Art Kramer on how, indeed, old dogs can learn new tricks…but at a slow­er pace than when we are younger. Which means, we need more patience, prac­tice, and motivation…perhaps you can com­bine trav­el with learn­ing that sec­ond language.

  23. spencer lord says

    February 23, 2009 at 9:35

    doidge’s book is superb. i read it three times.

  24. linda berger MA.Ed says

    April 1, 2009 at 12:47

    I am on the senior advi­so­ry com­mit­tee at the Jewish
    Com­mu­ni­ty Cen­ter, in St. Louis, Mis­souri. Do you pro­vide infor­ma­tion to any­one from the St. louis area?

  25. www.becomeataxidriver.org.uk says

    May 19, 2009 at 5:38

    im a lon­don cab­bie, i always sus­pect­ed i had more pow­er than bus drivers 😉

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