Thanks to our 3-month-old daugh­ter, my wife and I have been learn­ing much about baby brains. Mostly learn­ing on the job, as you can imagine.

We just watched a very nice PBS series titled Secret Life of the Brain that cov­ers brain devel­op­ment across the lifes­pan: babies, kids, teenagers, adults, seniors. A bit dated (2002) but excel­lent watch­ing even today.

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A few col­leagues referred me over the week­end to a very nice arti­cle at busi­ness pub­li­ca­tion Port­fo­lio.

While the arti­cle does an excel­lent job at intro­duc­ing the reader to the con­cept and promise of com­put­er­ized cog­ni­tive assess­ments, it also con­tributes to the mythol­ogy of “Brain Age”.

Let’s first take a look at the arti­cle How Smart Are You: The busi­ness of assess­ing cog­ni­tion and mem­ory is mov­ing from test­ing brain-impaired patients to assess­ing healthy peo­ples’ brains online.

A cou­ple of quotes:

- “Cog­ni­tive Drug Research is one a hand­ful of busi­nesses, most of them out­side of the U.S., that work with phar­ma­ceu­ti­cal com­pa­nies to test how new drugs for every­thing from nico­tine addic­tion to Alzheimer’s dis­ease affect the mind’s abil­ity to remem­ber things, make deci­sions, and ana­lyze information.”

- “Cog­ni­tive tests have been around for a cen­tury as exam­i­na­tions taken with paper and pen­cil. In the 1970s and ‘80s the tests shifted to com­put­ers, Cog­ni­tive Drug Research founder Keith Wesnes says.

So far, so good. In fact, one of the key high­lights from the mar­ket report we released in March was that “Large-scale, fully-automated cog­ni­tive assess­ments are being used in a grow­ing num­ber of clin­i­cal tri­als. This opens the way for the devel­op­ment of inex­pen­sive consumer-facing, base­line cog­ni­tive assess­ments.” And we pro­filed a few lead­ing com­pa­nies in the space: Brain Resource Com­pany, Cog­ni­tive Drug Research, CNS Vital Signs and CogState.

Now, the arti­cle is accom­pa­nied by a 5–7 minute quick test that promises to give us our “Brain Age”. And this doesn’t come from Nin­tendo, but from Cog­ni­tive Drug Research, a respected science-based company.

You can check it out Read the rest of this entry »

I wrote this arti­cle for the March/ April edi­tion of the pub­li­ca­tion Aging Today, pub­lished by the Amer­i­can Soci­ety on Aging, and received per­mis­sion to repro­duce it here.

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In recent years, most pro­fes­sion­als in aging have become aware of the grow­ing sci­en­tific evi­dence show­ing that human brains retain the abil­ity to gen­er­ate neu­rons and change over a life­time, dis­cov­er­ies that have bro­ken the sci­en­tific par­a­digm preva­lent dur­ing the 20th cen­tury. Fur­ther­more, neu­roimag­ing and cog­ni­tive train­ing stud­ies are show­ing how well-directed exer­cise presents peo­ple major oppor­tu­ni­ties for healthy brain aging.

How can peo­ple use emerg­ing tech­nolo­gies to keep their brains healthy and pro­duc­tive as long as pos­si­ble? An emerg­ing mar­ket for brain health– $225 mil­lion mar­ket in 2007, in the United States alone, of which con­sumers account for $80 million–is try­ing to address that ques­tion in a way that com­ple­ments other impor­tant more tra­di­tional pil­lars (and multi-billion indus­tries) of brain health, such as phys­i­cal exer­cise, bal­anced diet, stress man­age­ment (stress has been shown to actu­ally kill neu­rons and reduce the rate of cre­ation of new ones) and over­all men­tal stim­u­la­tion and life­long learning.

2007 AN ACTIVE YEAR

A series of impor­tant events took place in 2007, a sem­i­nal year for the brain health field, begin­ning in Jan­u­ary when many main­stream media pub­li­ca­tions, such as Time Mag­a­zine and CBS News, started to pub­lish major sto­ries on neu­ro­plas­tic­ity and brain exer­cise. This media cov­er­age fol­lowed the pub­li­ca­tion of the long-awaited results from national clin­i­cal tri­als show­ing that sig­nif­i­cant per­cent­ages of the par­tic­i­pants age 65 and older who trained for five weeks improved their mem­ory, rea­son­ing and information-processing speed. Find­ings from the Advanced Cog­ni­tive Train­ing for Inde­pen­dent and Vital Elderly (ACTIVE) Study appeared in the Jour­nal of the Amer­i­can Med­ical Asso­ci­a­tion (Dec. 20, 2006) and revealed that even after five years, par­tic­i­pants in the ACTIVE computer-based pro­gram showed less of a decline in information-processing skills than those in a con­trol group that received no cog­ni­tive training.

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We are proud to announce that Sharp­Brains has joined the soon-to-be-launched Sci­en­tific Amer­i­can Part­ner Net­work. This won’t change any­thing in our day-to-day oper­a­tions.

Also, please visit us tomor­row Mon­day to read a superb arti­cle on Sleep and the Brain by Shan­non Mof­fett, author of the superb book The Three Pound Enigma: The Human Brain and the Quest to Unlock its Mys­ter­ies. Mof­fett recently appeared on the PBS spe­cial The Brain Fit­ness Pro­gram, which aired nation­wide on PBS.

Have a nice Sunday!

“How does this neuro fron­tier inside our skulls specif­i­cally inform law firm man­age­ment? By peer­ing inside the brain, we can see how its owner takes in infor­ma­tion, makes deci­sions, changes and resists change, remem­bers and recalls, and responds to peo­ple. What we are learn­ing about the brain affects three fac­tors crit­i­cal to law firms and to each indi­vid­ual lawyer: con­trol, com­mu­ni­ca­tion, and com­pe­tence. Let’s take a tour of some of what’s been learned and see how the new infor­ma­tion can be useful.”

This is part of the great arti­cle that Dr. Jef­frey M. Schwartz and Stephanie West Allen have writ­ten for the Feb­ru­ary, 2007 edi­tion of Of Coun­sel: The Legal Prac­tice and Man­age­ment Report, titled “Brain Man­age­ment: Law Firm Lead­er­ship on the Neuro Fron­tier” (Not avail­able online.)

You can read a bit more in Stephanie’s blog (a must-read blog for lawyers).   

In short: our actions can change our brains. Actu­ally, our thoughts can do so too. We all can ben­e­fit from “self-directed neuroplasticity”-which requires prac­tice, imag­i­na­tion and empa­thy. The arti­cle men­tions spe­cific exam­ples for lawyers.

Learn­ing assumes and induces neu­ro­plas­tic­ity (how the brain changes).

How can you apply this to your occu­pa­tion? what have you learned today?

You can read more on a sim­i­lar topic, by Dr. Jef­frey M. Schwartz and David Rock: check out The Neu­ro­science of Lead­er­ship.

 

 

Dr. Elkhonon Gold­berg is a clin­i­cal pro­fes­sor of neu­rol­ogy at New York Uni­ver­sity School of Med­i­cine, and author of over 50 peer-reviewed papers. His areas of exper­tise include exec­u­tive func­tions, mem­ory, atten­tion deficit dis­or­der, demen­tia, trau­matic brain injury, and oth­ers. Dr. Gold­berg was a stu­dent and close asso­ciate of the great neu­ropsy­chol­o­gist Alexan­der Luria. His book The Exec­u­tive Brain: Frontal Lobes and the Civ­i­lized Mind (Oxford Uni­ver­sity Press, 2001) has received crit­i­cal acclaim and has been pub­lished in 12 lan­guages. His recent book The Wis­dom Para­dox: How Your Mind Can Grow Stronger As Your Brain Grows Older (Gotham Books, Pen­guin, 2005) offers an inno­v­a­tive under­stand­ing of cog­ni­tive aging and what can be done to fore­stall cog­ni­tive decline. It has been, or is in the process of being, pub­lished in 13 languages.

We are for­tu­nate that Dr. Gold­berg is Sharp­Brains Co-Founder and Chief Sci­en­tific Advi­sor. His book The Wis­dom Para­dox inspired me to embark in this path, and has been a key sound­ing board in the devel­op­ment of what we are doing.

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Key take-aways

- “Use It and Get More of It” reflects real­ity bet­ter than “Use It or Lose It”.

- Let’s demys­tify cog­ni­tion and the brain. Every­one needs to have a basic under­stand­ing of the brain-and how to cul­ti­vate it.

- Well-directed men­tal exer­cise is a must for cog­ni­tive enhance­ment and healthy aging.
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