Study shows men­tal agility game slows cog­ni­tive decline in older peo­ple (Iowa Now): “Wolin­sky and col­leagues sep­a­rated 681 gen­er­ally healthy med­ical patients in Iowa into four groups—each fur­ther sep­a­rated into those 50 to 64 years of age and those over age 65. One group was given com­put­er­ized cross­word puz­zles, while three other groups were exposed to a video game called Read the rest of this entry »

‘Chemo Brain’ After Breast Can­cer Backed by Study (US News):

“Breast can­cer patients treated with chemother­apy are at risk for mild men­tal deficits known col­lec­tively as “chemo brain,” a new study finds. Researchers at the Mof­fitt Can­cer Cen­ter in Tampa, Fla., reviewed exist­ing research on brain func­tion (“cog­ni­tive” func­tion­ing) in Read the rest of this entry »

In an increas­ingly knowledge-based and innovation-driven econ­omy, human brains—not finan­cial capital—are becom­ing the pri­mary dri­vers of busi­ness suc­cess. Engaged, cre­ative cit­i­zens and work­ers mean the dif­fer­ence between suc­cess and fail­ure at the orga­ni­za­tional and soci­etal levels.

Look­ing at the prob­lem from the per­spec­tive of brain health, there are Read the rest of this entry »

Ontario says tougher rules expected for dri­vers with demen­tia (Toronto Star):

- “In the wake of a Star series on dri­vers with cog­ni­tive impair­ment, Chiarelli pre­dicted there will be a “tight­en­ing across the board” of the sys­tem that allows many seniors with demen­tia to drive unchecked.”

- “The min­istry is con­sid­er­ing mak­ing the fol­low­ing changes: bet­ter train­ing for fam­ily doc­tors on report­ing cog­ni­tively impaired patients who drive; more rig­or­ous on-road test­ing of senior dri­vers; and the intro­duc­tion of grad­u­ated licens­ing for some seniors who, like teenage dri­vers, would not be allowed to drive at night or on 400-series high­ways.” Read the rest of this entry »

In recent years, we have wit­nessed the begin­nings of a rev­o­lu­tion in edu­ca­tion.  Tech­nol­ogy has fun­da­men­tally altered the way we do many things in daily life, but it is just start­ing to make head­way in chang­ing the way we teach.  Just as tele­vi­sion shows like Sesame Street enhanced the pas­sive learn­ing of infor­ma­tion for kids by teach­ing in a fun for­mat, elec­tronic games offer to greatly enhance the way kids and adults are taught by actively engag­ing them in the process. Read the rest of this entry »

Dr. Michael Merzenich, Emer­i­tus Pro­fes­sor at UCSF, is a lead­ing pio­neer in brain plas­tic­ity research. In the late 1980s, Dr. Merzenich was on the team that invented the cochlear implant. In 1996, he was the found­ing CEO of Sci­en­tific Learn­ing Cor­po­ra­tion (Nas­daq: SCIL), and in 2004 became co-founder and Chief Sci­en­tific Offi­cer of Posit Sci­ence. He was elected to the National Acad­emy of Sci­ences in 1999 and to the Insti­tute of Med­i­cine this year. He retired as Fran­cis A. Sooy Pro­fes­sor and Co-Director of the Keck Cen­ter for Inte­gra­tive Neu­ro­science at the Uni­ver­sity of Cal­i­for­nia at San Fran­cisco in 2007. You may have learned about his work in one of PBS TV spe­cials, mul­ti­ple media appear­ances, or neuroplasticity-related books.

(Alvaro Fer­nan­dez) Dear Michael, thank you very much for agree­ing to par­tic­i­pate in the inau­gural Sharp­Brains Sum­mit in Jan­u­ary, and for your time today. In order to con­tex­tu­al­ize the Summit’s main themes, I would like to focus this inter­view on the likely big-picture impli­ca­tions dur­ing the next 5 years of your work and that of other neu­ro­plas­tic­ity research and indus­try pioneers.

Thank you for invit­ing me. I believe the Sharp­Brains Sum­mit will be very use­ful and stim­u­lat­ing, you are gath­er­ing an impres­sive group together. I am look­ing for­ward to January.

Neuroplasticity-based Tools: The New Health & Well­ness Frontier

There are many dif­fer­ent technology-free approaches to har­ness­ing –enabling, dri­ving– neu­ro­plas­tic­ity. What is the unique value that tech­nol­ogy brings to the cog­ni­tive health table?

It’s all about effi­ciency, scal­a­bil­ity, per­son­al­iza­tion, and assured effec­tive­ness. Tech­nol­ogy sup­ports the imple­men­ta­tion of near-optimally-efficient brain-training strate­gies. Through the Inter­net, it enables the low-cost dis­tri­b­u­tion of these new tools, any­where out in the world. Tech­nol­ogy also enables the per­son­al­iza­tion of brain health train­ing, by pro­vid­ing sim­ple ways to mea­sure and address indi­vid­ual needs in each person’s brain-health train­ing expe­ri­ence. It enables assess­ments of your abil­i­ties that can affirm that your own brain health issues have been effec­tively addressed.

Of course sub­stan­tial gains could also be achieved by orga­niz­ing your every­day activ­i­ties that grow your neu­ro­log­i­cal abil­i­ties and sus­tain your brain health. Still, if the ordi­nary cit­i­zen is to have any real chance of main­tain­ing their brain fit­ness, they’re going to have to spend con­sid­er­able time at the brain gym!

One espe­cially impor­tant con­tri­bu­tion of tech­nol­ogy is the scal­a­bil­ity that it pro­vides for deliv­er­ing brain fit­ness help out into the world. Think about how effi­cient the drug deliv­ery sys­tem is today. Doc­tors pre­scribe drugs, insur­ance cov­ers them, and there is a drug store in every neigh­bor­hood in almost every city in the world so that every patient has access to them. Once neuroplasticity-based tools and out­comes and stan­dard­ized, we can envi­sion a sim­i­lar sce­nario. And we don’t need all those drug stores, because we have the Internet!

Hav­ing said this, there are obvi­ous obsta­cles. One main one, in my mind, is the lack of under­stand­ing of what these new tools can do. Cog­ni­tive train­ing pro­grams, for exam­ple, seem counter-intuitive to con­sumers and many pro­fes­sion­als “ why would one try to improve speed-of-processing if all one cares about is œmem­ory? A sec­ond obvi­ous prob­lem is to get indi­vid­u­als to buy into the effort required to really change their brains for the bet­ter. That buy-in has been achieved for many indi­vid­u­als as it applies to their phys­i­cal health, but we haven’t got­ten that far yet in edu­cat­ing the aver­age older per­son that brain fit­ness train­ing is an equally effort­ful business!

Tools for Safer Dri­ving: Teens and Adults

Safe dri­ving seems to be one area where the ben­e­fits are more intu­itive, which may explain the sig­nif­i­cant traction.

Yes, we see great poten­tial and inter­est among insur­ers for improv­ing dri­ving safety, both for seniors and teens. Appro­pri­ate cog­ni­tive train­ing can lower at-fault acci­dent rates. You can mea­sure clear ben­e­fits in rel­a­tively short time frames, so it won’t take long for insur­ers to see an eco­nomic ratio­nale to not only offer pro­grams at low cost or for free but to incen­tivize dri­vers to com­plete them. All­state, AAA, State Farm and other insur­ers are begin­ning to real­ize this poten­tial. It is impor­tant to note that typ­i­cal acci­dents among teens and seniors are dif­fer­ent, so that train­ing method­olo­gies will need to be dif­fer­ent for dif­fer­ent high-risk populations.

Yet, most dri­ving safety ini­tia­tives today still focus on edu­cat­ing dri­vers, rather that train­ing them neu­ro­log­i­cally. We mea­sure vision, for exam­ple, but com­pletely ignore atten­tional con­trol abil­i­ties, or a driver’s use­ful field of view. I expect this to change sig­nif­i­cantly over the next few years.

Long-term care and health insur­ance com­pa­nies will ulti­mately see sim­i­lar ben­e­fits, and we believe that they will fol­low a sim­i­lar course of action to reduce gen­eral med­ical and neu­rode­gen­er­a­tive dis­ease– (Mild Cog­ni­tive Impair­ment and Alzheimer’s– and Parkinsons-) related costs. In fact, many senior liv­ing com­mu­ni­ties are among the pio­neers in this field.

Boomers & Beyond: Main­tain­ing Cog­ni­tive Vitality

Main­stream media is cov­er­ing this emerg­ing cat­e­gory with thou­sands of sto­ries. But most cov­er­age seems still focused on does it work? more than “how do we define It”, what does work mean? or work for whom, and for what? Can you sum­ma­rize what recent research suggests?

We have seen clear pat­terns in the appli­ca­tion of our train­ing pro­grams, some pub­lished (like IMPACT), some unpub­lished, some with healthy adults, and some with peo­ple with mild cog­ni­tive impair­ment or early Alzheimers Dis­ease (AD). What we see in every case: Read the rest of this entry »

This is a par­tial list of the lit­er­a­ture we reviewed dur­ing the research phase of our new book, The Sharp­Brains Guide to Brain Fit­ness.  We know many friends of Sharp­Brains are researchers, health­care pro­fes­sion­als, graduate/ Ph.D. stu­dents, who want have direct access to the ref­er­ences (per­haps PubMed should pro­mote itself as a never end­ing source of men­tal stim­u­la­tion?), so here you have this list, orga­nized by rel­e­vant chap­ter. Please note that the list below appears in the book — whose man­u­script we had to close in Jan­u­ary 2009.

Intro­duc­tion

Basak, C. et al. (2008). Can train­ing in a real-time strat­egy video game atten­u­ate cog­ni­tive decline in older adults? Psy­chol­ogy and Aging.
Beg­ley, S. (2007). Train your mind, change your brain: How a new sci­ence reveals our extra­or­di­nary poten­tial to trans­form our­selves. Bal­lan­tine Books.
DeKosky, S. T., et al. (2008). Ginkgo biloba for pre­ven­tion of demen­tia: a ran­dom­ized con­trolled trial. Jour­nal of the Amer­i­can Med­ical Asso­ci­a­tion, 300, 2253–2262.
Doidge, N. (2007). The Brain that changes itself: Sto­ries of per­sonal tri­umph from the fron­tiers of brain sci­ence. Viking Adult.

Chap­ter 1. The Brain and Brain Fit­ness 101

Bunge, S. A., & Wright, S. B. (2007). Neu­rode­vel­op­men­tal changes in work­ing mem­ory and cog­ni­tive con­trol. Cur­rent Opin­ion In Neu­ro­bi­ol­ogy, 17(2), 243–50.
Dama­sio, A. (1995). Descartes error: Emo­tion, rea­son, and the human brain. Pen­guin Press.
David Kolb, D. (1983). Expe­ri­en­tial learn­ing: Expe­ri­ence as the source of learn­ing and devel­op­ment. FT Press.
Dra­gan­ski, B., Gaser, C., Kem­per­mann, G., Kuhn, H. G., Win­kler, J., Buchel, C., & May A. (2006). Tem­po­ral and spa­tial dynam­ics of brain struc­ture changes dur­ing exten­sive learn­ing. The Jour­nal of Neu­ro­science, 261231, 6314–6317.
Gage, F. H., Kem­per­mann, G., & Song, H. (2007). Adult Neu­ro­ge­n­e­sis. Cold Spring Har­bor Lab­o­ra­tory Press, NY.
Gard­ner, H. (1983). Frames of Mind: The the­ory of mul­ti­ple intel­li­gences. New York: Basic Books.
Gaser, C. & Schlaug, G. (2003). Brain struc­tures dif­fer between musi­cians and non-musicians. The Jour­nal of Neu­ro­science, 23, 9240–9245. Read the rest of this entry »