Digital therapeutics pioneer Akili Interactive Labs goes public, raising $150M+; trades down 49% first day

Akili Inter­ac­tive is the lat­est com­pa­ny to go pub­lic via SPAC deal (Boston Busi­ness Jour­nal): Boston’s Akili Inter­ac­tive Labs Inc. is the lat­est Mass­a­chu­setts-based com­pa­ny to go pub­lic after com­plet­ing a reverse merg­er — in a year of mar­ket tur­moil that saw few local firms pass­ing the thresh­old between pri­vate and pub­lic sta­tus. Shares of…

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Digital therapeutics pioneer Akili Interactive plans to go public in mid-2022 at a $1B valuation

Pal­i­hapi­tiya-Led SPAC to Merge With Akili in $1 Bil­lion Deal (Bloomberg): Akili Inter­ac­tive, a start­up that has devel­oped a video game to help treat atten­­tion-deficit dis­or­ders in kids, has agreed to go pub­lic through a merg­er with one of Chamath Palihapitiya’s blank-check com­pa­nies. The deal, which con­firms a Bloomberg News report, val­ues the com­bined entity…

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Study: Personalized, closed-loop neuromodulation can (one day) become a “pacemaker for the brain”

Treat­ing Severe Depres­sion with On-Demand Brain Stim­u­la­tion (UCSF press release): UCSF Health physi­cians have suc­cess­ful­ly treat­ed a patient with severe depres­sion by tap­ping into the spe­cif­ic brain cir­cuit involved in depres­sive brain pat­terns and reset­ting them using the equiv­a­lent of a pace­mak­er for the brain. “This study points the way to a new par­a­digm that is…

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Click Therapeutics and Boehringer Ingelheim partner to develop and market a digital therapeutic to treat schizophrenia

Boehringer Ingel­heim, Click Ther­a­peu­tics ink $500M+ dig­i­tal ther­a­peu­tics devel­op­ment, com­mer­cial­iza­tion deal (Mobi­Health­News): Inter­na­tion­al phar­ma Boehringer Ingel­heim and pre­scrip­tion dig­i­tal ther­a­peu­tics com­pa­ny Click Ther­a­peu­tics have inked a $500 mil­lion-plus deal to joint­ly devel­op and com­mer­cial­ize a dig­i­tal treat­ment for patients with schizophrenia.

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Survey finds ischaemic stroke and altered mental status as most common neurological complications in severe COVID-19 cases

Brain dam­age, psy­chi­atric prob­lems report­ed in severe coro­n­avirus cas­es, study says (Mia­mi Her­ald): A new study shows that severe cas­es of the coro­n­avirus can cause strokes and oth­er neu­ro­log­i­cal issues, or an “altered men­tal state” for patients. The research, pub­lished in the British med­ical jour­nal Lancet Psy­chi­a­try, looked at a small pool of severe COVID-19…

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Epigenetics research opens potential door to prevent neurodevelopmental disorders

___ Epi­ge­net­ic Changes Guide Devel­op­ment of Dif­fer­ent Brain Regions (Dana Foun­da­tion): “It’s one of the great­est stand­ing mys­ter­ies in neu­ro­science: Giv­en that each cell in the human body con­tains the same DNA, how, exact­ly, does the brain devel­op into dis­tinct func­tion­al regions, sup­port­ed by dif­fer­ent cell types? And how might that devel­op­men­tal pro­gram go awry,…

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