A conversation at the frontier of digital health innovation, FDA regulations, and cognitive health

Dig­i­tal Ther­a­peu­tics for MCI and Alzheimer’s dis­ease: A Reg­u­la­to­ry Per­spec­tive (The Jour­nal of Pre­ven­tion of Alzheimer’s Dis­ease): –This arti­cle is adapt­ed from a com­pre­hen­sive con­ver­sa­tion between Dr. Murali Doraiswamy and Dr. Jef­frey Shuren at the 2021 Clin­i­cal Tri­als on Alzheimer’s Dis­ease (CTAD) con­fer­ence in Boston. Dr. Shuren is a behav­ioral neu­rol­o­gist who has held a variety…

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The new frontier in neurocognitive monitoring and dementia screening: the Apple Watch

Bio­gen to Launch Pio­neer­ing Study to Devel­op Dig­i­tal Bio­mark­ers of Cog­ni­tive Health Using Apple Watch and iPhone (press release): Bio­gen Inc. (Nas­daq: BIIB) today announced a new vir­tu­al research study, in col­lab­o­ra­tion with Apple, to inves­ti­gate the role Apple Watch and iPhone could play in mon­i­tor­ing cog­ni­tive per­for­mance and screen­ing for decline in cog­ni­tive health…

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Anticholinergic drugs found to significantly increase risk of cognitive decline, especially among those with Alzheimer’s Disease biomarkers or genetic predisposition

Com­mon Class of Drugs Linked to Increased Risk of Alzheimer’s Dis­ease (UC San Diego release): A team of sci­en­tists, led by researchers at Uni­ver­si­ty of Cal­i­for­nia San Diego School of Med­i­cine, report that a class of drugs used for a broad array of con­di­tions, from aller­gies and colds to hyper­ten­sion and uri­nary incon­ti­nence, may be…

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Brain scans show lower accumulation of tau and amyloid pathology among cognitive “super-agers”

Super-Agers Show Resis­tance to Tau and Amy­loid Accu­mu­la­tion, Main­tain High Cog­ni­tive Func­tion (Soci­ety of Nuclear Med­i­cine and Mol­e­c­u­lar Imag­ing press release): Super-agers, or indi­vid­u­als whose cog­ni­tive skills are above the norm even at an advanced age, have been found to have increased resis­tance to tau and amy­loid pro­teins, accord­ing to research pre­sent­ed at the Society…

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Study: Practice effect due to repeated testing can delay detection of cognitive impairment and dementia

___ Prac­tice Imper­fect: Repeat­ed Cog­ni­tive Test­ing Can Obscure Ear­ly Signs of Demen­tia (UC San Diego Health press release): “Alzheimer’s dis­ease (AD) is a pro­gres­sive, neu­rode­gen­er­a­tive con­di­tion that often begins with mild cog­ni­tive impair­ment or MCI, mak­ing ear­ly and repeat­ed assess­ments of cog­ni­tive change cru­cial to diag­no­sis and treat­ment. But in a paper pub­lished online in…

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