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SSRI antidepressants linked to increased risk of stroke

Anti­de­pres­sants linked to risk of brain bleeds (Chicago Tribune):

Peo­ple using a com­mon class of anti­de­pres­sants may have slightly increased odds of suf­fer­ing bleed­ing in the brain — though the risk is still very small, researchers reported Wednesday…The anti­de­pres­sants are known as selec­tive sero­tonin reup­take inhibitors (SSRIs), and include widely used drugs like flu­ox­e­tine (Prozac), ser­tra­line (Zoloft), citalo­pram (Celexa) and parox­e­tine (Paxil).”

Study: Selec­tive sero­tonin reup­take inhibitors and brain hem­or­rhage (Neu­rol­ogy). From the Abstract:

  • Objec­tive: We syn­the­sized the epi­demi­o­logic evi­dence con­cern­ing selec­tive sero­tonin reup­take inhibitor (SSRI) expo­sure and the risk of CNS hemorrhage.
  • Con­clu­sions: SSRI expo­sure is asso­ci­ated with an increased risk of intrac­ere­bral and intracra­nial hem­or­rhage, yet given the rar­ity of this event, absolute risks are likely to be very low.

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