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SSRI antidepressants linked to increased risk of stroke

Antidepressants linked to risk of brain bleeds (Chicago Tribune):

“People using a common class of antidepressants may have slightly increased odds of suffering bleeding in the brain – though the risk is still very small, researchers reported Wednesday…The antidepressants are known as selective serotonin reuptake inhibitors (SSRIs), and include widely used drugs like fluoxetine (Prozac), sertraline (Zoloft), citalopram (Celexa) and paroxetine (Paxil).”

Study: Selective serotonin reuptake inhibitors and brain hemorrhage (Neurology). From the Abstract:

  • Objective: We synthesized the epidemiologic evidence concerning selective serotonin reuptake inhibitor (SSRI) exposure and the risk of CNS hemorrhage.
  • Conclusions: SSRI exposure is associated with an increased risk of intracerebral and intracranial hemorrhage, yet given the rarity of this event, absolute risks are likely to be very low.

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