An impres­sive recent ref­er­ence book on the future of brain care is Inte­gra­tive Neu­ro­science and Per­son­al­ized Med­i­cine, edited by Evian Gor­don and Stephen H. Koslow (Oxford Uni­ver­sity Press; $89.95).

Book descrip­tion: This book takes an in depth and hard look at the cur­rent sta­tus and future direc­tion of treat­ment pre­dic­tive mark­ers in Per­son­al­ized Med­i­cine for the brain from the per­spec­tives of the researchers on the cut­ting edge and those involved in health­care imple­men­ta­tion. The con­tents pro­vide a com­pre­hen­sive text suit­able as both a pithy intro­duc­tion to and a clear sum­mary of the “sci­ence to solu­tions” con­tin­uum in this devel­op­ing field of Per­son­al­ized Med­i­cine and Inte­gra­tive Neu­ro­science. The sci­ence includes both mea­sures of genes using whole genome approaches and SNIPS as well as BRAIN­mark­ers of direct brain func­tion such as brain imag­ing, bio­phys­i­cal changes and objec­tive cog­ni­tive and behav­ioral mea­sure­ments. More infor­ma­tion below.

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36-Hour Offer

Dr. Evian Gor­don will speak at the upcom­ing 2011 Sharp­Brains Sum­mit: Retool­ing Brain Health for the 21st Cen­tury (March 30th — April 1st) and his firm, Brain Resource, is among Sum­mit Spon­sors. Thanks to his sup­port, we are pleased to announce the fol­low­ing offer: TEN pro­fes­sion­als who reg­is­ter to attend the 2011 Sharp­Brains Sum­mit over the next 36 hours, from now until Fri­day March 4th, 7pm US Pacific Time, will each receive a com­pli­men­tary hard­copy of the book Inte­gra­tive Neu­ro­science and Per­son­al­ized Med­i­cine. If more than ten peo­ple reg­is­ter by then, we will select ten names at random.

We are also pleased to announce the addi­tion of 12 new Speak­ers and Mod­er­a­tors to the 2011 Sharp­Brains Sum­mit — the result­ing agenda is turn­ing out to be noth­ing short of spec­tac­u­lar (in our, yes, a bit biased judgment):

• Alexan­dra More­house, CMO, AAA North California
• Dr. Evian Gor­don, CEO, Brain Resource
• Kath­leen Herath, Asst Vice Pres­i­dent, Nation­wide Insurance
• Dr. David Tal, Direc­tor, A.G.E. Mat­ters Clinic
• Paula Psyl­lakis, Senior Pol­icy Advi­sor, Ontario Min­istry of Research and Innovation
• Veronika Litin­ski, Advi­sor, MaRS Life Sci­ences and Health Care
• Dr. Joshua Stein­er­man, Assis­tant Pro­fes­sor, Albert Ein­stein Col­lege of Medicine
• Dr. Jef­frey Kaye, Direc­tor, NIA — ORCATECH
• Dr. John Rep­pas, Pol­icy Direc­tor, Neu­rotech­nol­ogy Indus­try Organization
• Dr. Justin Mar­ley, Chair Men­tal Health Infor­mat­ics Group, UK Royal Col­lege of Psychiatrists
• Dr. David Darby, Chief Med­ical Offi­cer, Cogstate
• Dr. John Hart, Med­ical Sci­ence Direc­tor, Cen­ter for Brain Health at UT-Dallas

-> Learn More and Reg­is­ter to Par­tic­i­pate in the Sum­mit Here, and get a chance at get­ting a com­pli­men­tary copy of the book Inte­gra­tive Neu­ro­science and Per­son­al­ized Med­i­cine!

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Prod­uct Descrip­tion (con­tin­ued): Each chap­ter pro­vides a review of recent rel­e­vant lit­er­a­ture; show the solu­tions achieved through inte­gra­tive neu­ro­science and appli­ca­tions in patient care thus pro­vid­ing a prac­ti­cal guide to the reader. The time­li­ness of this book’s con­tent is pro­pi­tious pro­vid­ing bot­tom line infor­ma­tion to edu­cate prac­tic­ing clin­i­cians, health care work­ers and researchers, and also a path­way for under­grad­u­ate and grad­u­ates inter­ested in fur­ther their under­stand­ing of and involve­ment in tai­lored per­sonal solutions.

“The way we cur­rently treat patients in all areas of med­i­cine leaves much to be desired. We iden­tify clus­ters of symp­toms in a descrip­tive man­ner, give those clus­ters a label that best fits, or sev­eral labels if none fits well, and then we admin­is­ter drugs that were them­selves, or their pre­de­ces­sors, dis­cov­ered by serendip­ity over fifty years ago… This type of cur­rent stan­dard of care is no longer accept­able. We need to bring the neu­ro­science dis­cov­er­ies of the last fifty years to health care and that must be done in a per­son­al­ized way, match­ing each patient to the best treat­ment that is specif­i­cally indi­vid­u­al­ized for that per­son. Gor­don & Koslow bring together in an exem­plary and much needed book…the stan­dards for the new sci­ence and evidence-based per­son­al­ized med­i­cine of the future that has been much expected and is finally tak­ing off.” — Julio Licinio, MD, Direc­tor, John Curtin School of Med­ical Research, CMBE, Aus­tralian National Uni­ver­sity, Can­berra, Australia.

About the Authors:

Dr. Stephen H. Koslow, PhD has been an inno­va­tor and cre­ative leader in the fields of psy­chophar­ma­col­ogy, neu­ro­science and infor­mat­ics. He has joined efforts in all these fields by now help­ing to cat­alyze Per­son­al­ized Med­i­cine into a real­ity. He con­tin­ues to run his own con­sult­ing com­pany, and his efforts in Neu­roin­for­mat­ics, and spe­cial inter­est in the clin­i­cal areas of men­tal ill­ness. He had worked for many years at the National Insti­tutes of Men­tal Health (NIMH) where he had a major lead­er­ship role in these same areas.

Dr. Evian Gor­don is Adjunct Asso­ciate Pro­fes­sor of Psy­chi­a­try at Syd­ney Med­ical School, Uni­ver­sity of Syd­ney. He is also the found­ing Direc­tor of the Brain Dynamic Cen­tre (BDC), and heads BDC’s Inte­gra­tive Neu­ro­science Pro­gram. He is also the CEO of Brain Resource, a pub­licly listed biotech Com­pany, which devel­oped out of BDC in 2001, and is now the indus­try affil­i­ate of BDC. He is a pio­neer of ‘inter­gra­tive neu­ro­science’ and has over 25 years in bring­ing together com­ple­men­tary human brain imag­ing tech­nolo­gies. With his expe­ri­ence he has estab­lished the first fully stan­dard­ized inter­na­tional data­base on the human brain, under the aus­pices of Brain Resource. He has over 350 peer-reviewed pub­li­ca­tions and has pro­duced a 14-part tele­vi­sion series on mod­els of the human brain.

Table of Contents:

PREFACE, Her­bert Pardes, MD
INTRODUCTION, Stephen H. Koslow, PhD and Evian Gor­don, MD, PhD

GENESIS OF PERSONALIZED MEDICINE
1. The His­tory of Per­son­al­ized Med­i­cine, Edward Abra­hams, Ph.D. and Michael Sil­ver
2. An Applied Con­text for Per­son­al­ized Med­i­cine in Psy­chi­a­try, Alan F. Schatzberg, MD
3. Per­son­al­ized Med­i­cine and Inte­gra­tive Neu­ro­science: Towards Con­sen­sus Mark­ers for Dis­or­ders of Brain Health, Leanne Williams, PhD and Evian Gor­don MD, PhD

PERSONALIZED MEDICINE AND MENTAL DISORDERS
4. Does fMRI have a role in per­son­al­ized health care for psy­chi­atric patients?, Alex For­nito, MD and Edward T. Bull­more, MD
5. Stress and the Impact of Per­son­al­ized Med­i­cine, Charles F. Gille­spie, M.D., PhD, Elis­a­beth B. Binder, MD, PhD, Paul E. Holtzheimer, MD, and Charles B. Nemeroff, MD, PhD
6. Per­son­al­ized Med­i­cine for Schiz­o­phre­nia, Jacob S. Bal­lon, MD, Ragy R. Gir­gis, MD, and Jef­frey A. Lieber­man, MD
7. Per­son­al­ized Inte­gra­tive Mark­ers for Atten­tion Deficit/Hyperactivity Dis­or­der in Chil­dren and Ado­les­cents, M. Kohn, MD, S. Clarke, MD and Leanne Williams, PhD

PERSONALIZED MEDICINE AND OTHER BRAIN DISORDERS
8. The Role of Neu­roimag­ing Bio­mark­ers in Per­son­alised Med­i­cine for Neuro-degenerative and Psy­chi­atric Dis­or­ders, Ellen M. Migo, Steve C. R. Williams, William R. Crum, Matthew J. Kemp­ton and Ulrich Ettinger
9. Auto­nomic Ner­vous Sys­tem Mark­ers for Psy­chophys­i­o­log­i­cal, Anx­i­ety and Phys­i­cal Dis­or­ders, Richard Gevirtz, Ph.D., BCIAC
10. Per­son­al­ized Med­i­cine in Sleep Health, Ronald Grun­stein, MD
11. Ther­a­nos­tics and Trans­la­tion towards Per­son­al­ized Med­i­cine for Mul­ti­ple Scle­ro­sis, Ariel Miller, Tamar Paperna, Opher Caspi, Izabella Lejbkow­icz, Else­beth Staun-Ram, Nili Avidan

PERSONALIZED MEDICINE AND HEALTH CARE
12. Brain-Related Health­care: New Mod­els for Per­son­al­ized Med­i­cine, David White­house, MD
13. Clin­i­cal Deci­sion Sup­port in Employee Assis­tance Pro­grams: Per­son­al­iz­ing the Ther­a­peu­tic Approach, Eugene Baker, PhD
14. Eco­nomic impacts of the Per­son­al­ized Med­i­cine Tsunami, Dan Segal and David Williams

CONCLUSION AND RECOMMENDATIONS
Accel­er­at­ing the Future of Per­son­al­ized Med­i­cine, Evian Gor­don, MD, PhD and Stephen H. Koslow, PhD

-> Learn More and Reg­is­ter to Par­tic­i­pate in the Sum­mit Here, and get a chance at get­ting a com­pli­men­tary copy of the book Inte­gra­tive Neu­ro­science and Per­son­al­ized Med­i­cine!

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